Toxicological profiles - Boron

TOXICOLOGICAL PROFILE FOR BORON......Page 1
CONTENTS......Page 5
DISCLAIMER......Page 2
FOREWORD......Page 3
LIST OF FIGURES......Page 8
LIST OF TABLES......Page 9
1.2 HOW MIGHT I BE EXPOSED TO BORON?......Page 10
1.4 HOW CAN BORON AFFECT MY HEALTH?......Page 11
1.7 WHERE CAN I GET MORE INFORMATION?......Page 12
2.2 DISCUSSION OF HEALTH EFFECTS BY ROUTE OF EXPOSURE......Page 13
2.2.1.2 Systemic Effects......Page 14
2.2.1.6 Reproductive Effects......Page 18
2.2.2.1 Death......Page 19
2.2.2.2 Systemic Effects......Page 20
2.2.2.3 Immunological Effects......Page 31
2.2.2.6 Reproductive Effects......Page 32
2.2.3.1 Death......Page 33
2.2.3.2 Systemic Effects......Page 34
2.3.1.3 Dermal Exposure......Page 36
2.3.4.3 Dermal Exposure......Page 37
2.4 RELEVANCE TO PUBLIC HEALTH......Page 38
2.5.1 Biomarkers Used to Identify and/or Quantify Exposure to Boron......Page 43
2.8 MITIGATION OF EFFECTS......Page 44
2.9 ADEQUACY OF THE DATABASE......Page 45
2.9.1 Existing Information on Health Effects of Boron......Page 46
2.9.2 Data Needs......Page 47
3.2 PHYSICAL AND CHEMICAL PROPERTIES......Page 50
4.3 USE......Page 57
5.2.1 Air......Page 58
5.2.2 Water......Page 59
5.3.1 Transport and Partitioning......Page 60
5.3.2.2 Water......Page 61
5.4.2 Water......Page 62
5.5 GENERAL POPULATION AND OCCUPATIONAL EXPOSURE......Page 63
5.7.1 Data Needs......Page 64
6.2 ENVIRONMENTAL SAMPLES......Page 66
6.3.2 On-going Studies......Page 70
7. REGULATIONS AND ADVISORIES......Page 71
8. REFERENCES......Page 75
In Vivo......Page 86
Reference Dose......Page 87
Uncertainty Factor......Page 88
User s Guide......Page 89
Acronyms, Abbreviations, and Symbols......Page 94
PEER REVIEW......Page 98