Toxicological profiles - Nitrobenzene

TOXICOLOGICAL PROFILE FOR NITROBENZENE......Page 1
CONTENTS......Page 5
DISCLAIMER......Page 2
FOREWORD......Page 3
LIST OF FIGURES......Page 8
LIST OF TABLES......Page 9
1.2 HOW MIGHT I BE EXPOSED TO NITROBENZENE?......Page 10
1.4 HOW CAN NITROBENZENE AFFECT MY HEALTH?......Page 11
1.5 WHAT LEVELS OF EXPOSURE HAVE RESULTED IN HARMFUL HEALTH EFFECTS?......Page 12
1.8 WHERE CAN I GET MORE INFORMATION?......Page 20
2.2 DISCUSSION OF HEALTH EFFECTS BY ROUTE OF EXPOSURE......Page 21
2.2.1.2 Systemic Effects......Page 22
2.2.1.4 Neurological Effects......Page 28
2.2.1.6 Reproductive Effects......Page 29
2.2.2.2 Systemic Effects......Page 30
2.2.2.6 Reproductive Effects......Page 34
2.2.3.2 Systemic Effects......Page 35
2.3.1.3 Dermal Exposure......Page 36
2.3.3 Metabolism......Page 37
2.4 RELEVANCE TO PUBLIC HEALTH......Page 38
2.5.1 Biomarkers Used to Identify and/or Quantify Exposure to Nitrobenzene......Page 42
2.7 POPULATIONS THAT ARE UNUSUALLY SUSCEPTIBLE......Page 43
2.8.2 Identification of Data Needs......Page 44
3.2 PHYSICAL AND CHEMICAL PROPERTIES......Page 48
4.4 DISPOSAL......Page 52
5.2 RELEASES TO THE ENVIRONMENT......Page 53
5.2.2 Water......Page 55
5.3.1 Transport and Partitioning......Page 56
5.3.2.2 Water......Page 58
5.3.2.3 Soil......Page 60
5.4.2 Water......Page 61
5.6 POPULATIONS WITH POTENTIALLY HIGH EXPOSURES......Page 62
5.7.1 Identification of Data Needs......Page 63
6. ANALYTICAL METHODS......Page 64
6.2 ENVIRONMENTAL SAMPLES......Page 65
6.3.1 Identification of Data Needs......Page 67
7. REGULATIONS AND ADVISORIES......Page 70
8. REFERENCES......Page 74
Developmental Toxicity......Page 96
Mutagen......Page 97
Teratogen......Page 98
User’s Guide......Page 99
Acronyms, Abbreviations, and Symbols......Page 104
Peer Review......Page 108