Seizure Prediction in Epilepsy: From Basic Mechanisms to Clinical Applications

Cover......Page 1
Seizure Prediction in Epilepsy......Page 2
Related Titles......Page 3
Title......Page 4
The Editors and Copyright......Page 5
Contents......Page 6
Preface......Page 15
Thanks......Page 17
List of Contributors......Page 18
Color Plates......Page 25
Unpredictability of Seizures and the Burden of Epilepsy......Page 34
The History of Seizure Prediction......Page 44
Impact of Computational Models for an Improved\rUnderstanding of Ictogenesis: From Single Neurons\rto Networks of Neurons......Page 58
Effective and Anatomical Connectivity in a Rat Model of\rSpontaneous Limbic Seizure......Page 78
Network Models of Epileptiform Activity: Explorations in Seizure\rEvolution and Alteration......Page 93
Recurrent Cortical Network Activity and Modulation of Synaptic\rTransmission......Page 114
Epilepsy as a Disease of the Dynamics of Neuronal\rNetworks – Models and Predictions......Page 127
Neuronal Synchronization and the ‘Ictio-centric’ vs the Network\rTheory for Ictiogenesis: Mechanistic and Therapeutic\rImplications for Clinical Epileptology......Page 138
Cellular Neural Networks and Seizure Prediction: An Overview......Page 145
Time Series Analysis with Cellular Neural Networks......Page 158
Intrinsic Cortical Mechanisms which Oppose Epileptiform\rActivity: Implications for Seizure Prediction......Page 176
Is Prediction of the Time of a Seizure Onset the Only Value\rof Seizure-prediction Studies?......Page 189
High-frequency Pre-seizure Activity and Seizure Prediction......Page 195
Characterizing the Epileptic Process with Stochastic Qualifiers\rof Brain Dynamics......Page 200
Bivariate and Multivariate Time Series Analysis Techniques\rand their Potential Impact for Seizure Prediction......Page 214
A Multivariate Approach to Correlation Analysis Based\ron Random Matrix Theory......Page 234
Seizure Prediction in Epilepsy: Does a Combination of Methods\rHelp?......Page 252
Can Your Prediction Algorithm Beat a Random Predictor?......Page 262
Testing a Prediction Algorithm: Assessment of Performance......Page 274
Considerations on Database Requirements for Seizure\rPrediction......Page 285
Beyond Prediction – Focal Cooling and Optical Activation\rto Terminate Focal Seizures......Page 292
Vagus Nerve and Hippocampal Stimulation for Refractory\rEpilepsy......Page 306
Responsive Neurostimulation for the Treatment of Epileptic\rSeizures......Page 321
Chronic Anterior Thalamic Deep-brain Stimulation\ras a Treatment for Intractable Epilepsy......Page 329
Thoughts about Seizure Prediction from the Perspective\rof a Clinical Neurophysiologist......Page 339
State of Seizure Prediction: A Report on Informal Discussions\rwith Participants of the Third International Workshop on Seizure\rPrediction......Page 346
index......Page 352