Viral gene therapy

preface_Viral Gene Therapy......Page 1
part_1......Page 13
01_Retroviral Vectors in Gene Therapy: Mechanism of Integration, Successes in Gene Therapy Trials, Emerging Problems and Potential Solutions......Page 15
02_Production of Retroviral and Lentiviral Gene Therapy Vectors: Challenges in the Manufacturing of Lipid Enveloped Virus......Page 27
03_Surface Modification of Retroviral Vectors for Gene Therapy......Page 53
04_The Glucocorticoid Receptor in Retroviral Infection......Page 85
part_2......Page 101
05_Adenoviral Vectors: Potential and Challenges as a Gene Delivery System......Page 103
06_Adenovirus-Based Gene Therapy for Cancer......Page 141
07_Recombinant Adenovirus Infection of Human Dendritic Cells......Page 161
08_Harnessing the Potential of Adenovirus Vectored Vaccines......Page 181
part_3......Page 205
09_AAV Mediated β-Thalassemia Gene Therapy......Page 207
10_Comparison of AAV Serotypes for Gene Delivery to Dopaminergic Neurons in the Substantia Nigra......Page 217
11_Progress and Challenges in AAV-Mediated Gene Therapy for Duchenne Muscular Dystrophy......Page 237
12_Viral Vectors as Tools to Investigate the Role of Dysregulated Proteins in Nervous System Pathologies: The Case of Acquired Motor Neuropathies......Page 253
part_4......Page 273
13_Designing Lentiviral Gene Vectors......Page 275
14_Gene Regulatable Lentiviral Vector System......Page 297
15_Dendritic Cells and Lentiviral Vectors: Mapping the Way to Successful Immunotherapy......Page 321
part_5......Page 365
16_Development and Application of HIV Vectors Pseudotyped with HIV Envelopes......Page 367
17_Highly Efficient Retrograde Gene Transfer for Genetic Treatment of Neurological Diseases......Page 383
18_Herpes Simplex Virus Type 1 for Use in Cancer Gene Therapy: Looking Backward to Move Forward......Page 393
19_Gene Therapy of Melanoma Using Inactivated Sendai Virus Envelope Vector (HVJ-E) with Intrinsic Anti-Tumor Activities......Page 433
20_Pharmacokinetic Study of Viral Vectors for Gene Therapy: Progress and Challenges......Page 447