Toxicological profiles - Jet fuels (jp4 and jp7)

TOXICOLOGICAL PROFILE FOR JET FUELS (JP4 AND JP7)......Page 1
CONTENTS......Page 8
DISCLAIMER......Page 2
UPDATE STATEMENT......Page 3
FOREWORD......Page 4
PEER REVIEW......Page 6
LIST OF FIGURES......Page 11
LIST OF TABLES......Page 12
1. PUBLIC HEALTH STATEMENT......Page 13
1.2 WHAT HAPPENS TO JET FUELS JP-4 AND JP-7 WHEN THEY ENTER THE ENVIRONMENT?......Page 14
1.5 HOW CAN JET FUELS JP-4 AND JP-7 AFFECT MY HEALTH?......Page 15
1.8 WHERE CAN I GET MORE INFORMATION?......Page 16
2.2 DISCUSSION OF HEALTH EFFECTS BY ROUTE OF EXPOSURE......Page 17
2.2.1.2 Systemic Effects......Page 18
2.2.1.5 Reproductive Effects......Page 34
2.2.2.1 Death......Page 35
2.2.2.7 Genotoxic Effects......Page 36
2.2.3.2 Systemic Effects......Page 37
2.2.3.8 Cancer......Page 43
2.3.3 Metabolism......Page 44
2.4 RELEVANCE TO PUBLIC HEALTH......Page 45
2.5 BIOMARKERS OF EXPOSURE AND EFFECT......Page 55
2.7 POPULATIONS THAT ARE UNUSUALLY SUSCEPTIBLE......Page 56
2.9 ADEQUACY OF THE DATABASE......Page 57
2.9.1 Existing Information on Health Effects of Jet Fuels JP-4 and JP-7......Page 58
2.9.2 Identification of Data Needs......Page 61
3.1 CHEMICAL IDENTITY......Page 64
3.2 PHYSICAL AND CHEMICAL PROPERTIES......Page 65
4.2 IMPORT/EXPORT......Page 87
4.4 DISPOSAL......Page 88
5.1 OVERVIEW......Page 89
5.2.2 Water......Page 90
5.2.3 Soil......Page 91
5.3.1 Transport and Partitioning......Page 92
5.3.2.2 Water......Page 95
5.3.2.3 Sediment and Soil......Page 96
5.4.2 Water......Page 97
5.6 POPULATIONS WITH POTENTIALLY HIGH EXPOSURES......Page 98
5.7.1 Identification of Data Needs......Page 99
6. ANALYTICAL METHODS......Page 101
6.2 ENVIRONMENTAL SAMPLES......Page 102
6.3.1 Identification of Data Needs......Page 106
7. REGULATIONS AND ADVISORIES......Page 107
8. REFERENCES......Page 111
Developmental Toxicity......Page 123
Mutagen......Page 124
Threshold Limit Value......Page 125
User’s Guide......Page 126
Acronyms, Abbreviations, and Symbols......Page 131