The Chemistry inside Spices & Herbs: Research and Development, Volume 2

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Title
Copyright
End User License Agreement
Contents
Foreword
Preface
List of Contributors
Drugs from Natural Sources in the Management of Skin Diseases
	Deepa S. Mandlik1 and Yogesh A. Kulkarni2,*
	INTRODUCTION
		Skin
		Skin Infections
	HERBS AND PHYTOCONSTITUENTS FOR THE TREATMENT OF SKIN DISEASES
		Atopic Dermatitis (AD)
		Psoriasis Vulgaris
		Acne Vulgaris
		Skin Pigmentation Disorders
		Skin Microbial Infections
		Skin Cancer
	CONCLUSION
	CONSENT FOR PUBLICATION
	CONFLICT OF INTEREST
	ACKNOWLEDGEMENT
	REFERENCES
Turmeric and Curcumin for Arthritis: Evidence for Their Therapeutic Use
	Avinash Kundadka Kudva1, Chethan B Shetty2, Naveen Joseph Mathai3, Prajwal Prabhudev Mane2, Nikku Mathew Geevarughese4 and Manjeshwar Shrinath Baliga5,*
	INTRODUCTION
		Plant-based Treatment for Arthritis
		Turmeric (Curcuma Longa Linn) and Arthritis
		Anti-arthritic Effects of Turmeric: Preclinical Studies
		Anti-arthritic Effects of Turmeric: Clinical Studies
		Mode of Action
		Free Radical Scavenging and Antioxidant Activity of Curcumin
		Anti-inflammatory Properties of Curcumin
		Curcumin Suppresses B Cell-activating Factor
		Curcumin Modulates Signal Transduction Pathways
		Curcumin Regulates Nuclear Transcription Factors
		Curcumin and Matrix Metalloproteinases
		Curcumin Stimulates Apoptosis of Synovial Fibroblasts
	CONCLUSION
	CONSENT FOR PUBLICATION
	CONFLICT OF INTEREST
	ACKNOWLEDGEMENT
	REFERENCES
Curcumin, the Principal Compound of Turmeric (Curcuma Longa Lin) in Oral Health: A Mini-Review
	Savita Lasrado1, Suresh Rao2, Lal Madathil2, Paul Simon2, Reewen George DSilva3 and Manjeshwar Shrinath Baliga2,*
	INTRODUCTION
		Curcumin and Gingivitis
		Curcumin and Ulcers
		Oral Lichen Planus and Curcumin
		Candidiasis and Curcumin
		Herpes Simplex Virus and Curcumin
		Curcumin and Periodontitis
		Leukoplakia and Curcumin
	CONCLUSION
	CONSENT FOR PUBLICATION
	CONFLICT OF INTEREST
	ACKNOWLEDGEMENT
	REFERENCES
Resveratrol in Osteoarthritis: A Memoir
	Naveen Joseph Mathai1, Chethan B Shetty2, Nikku Mathew Geevarughese3, Prajwal Prabhudev Mane2, Errol Moras4 and Manjeshwar Shrinath Baliga5,*
	INTRODUCTION
		Pathology
		Role of Resveratrol and NF-κβ
		Animal Studies on Resveratrol
		Human Studies on Resveratrol
	CONCLUSION
	CONSENT FOR PUBLICATION
	CONFLICT OF INTEREST
	ACKNOWLEDGEMENT
	REFERENCES
Piperine: An Alkaloid from Piper Species with a Wide Range of Therapeutic Properties
	Sunita Singh1,*
	INTRODUCTION
	ISOLATION TECHNIQUES OF PIPERINE FROM PEPPER
		Chemistry of Piperine
		Pharmacokinetics of Piperine
	THERAPEUTIC PROPERTIES OF PIPERINE
		Antioxidant Properties
		Importance of Antioxidant Potential
		Anti-Inflammatory Properties
		Anti-diabetic Properties
		Neuroprotective Properties
		Anti-cancerous Properties
		Lung Cancer
		Genital Cancers
			Prostate Cancer
			Cervical and Ovarian Cancer
			Cancers of the Gastrointestinal Tract
			Breast Cancer
			Other Cancer Types
		Antimutagenic and Tumor Inhibitory Properties
		Other Physiological Properties
		Antimicrobial Properties
		Bioavailability Enhancing Effect of Piperine
		Advantage of Using Piperine as Bioenhancer
		Piperine Interactions with Drugs
		Proposed Mechanism for Bioenhancing Effect
			By Action on Drug Metabolizing Enzyme
			By Affecting the Blood Supply to GIT and Membrane Fluidity
			By Enhancing Drug Transport
		Marketed Product of Piperine as Bioenhancer with Drug
	STRUCTURE-ACTIVITY RELATIONSHIP OF PIPERINE AND ITS ANALOGS
	TOXICITY DATA RELATED TO PIPERINE
	CURRENT DEVELOPMENTS AND FUTURE PERSPECTIVES
	CONSENT FOR PUBLICATION
	CONFLICT OF INTEREST
	ACKNOWLEDGEMENT
	REFERENCES
Fenugreek (Trigonella foenum-graecum L.): A Palatable Spice, An Active Herb, A Promising Functional Food, and Even More
	Alev Onder1,*, Ahsen Sevde Cinar1,2 and Serap Gur3
	INTRODUCTION
	TRADITIONAL USAGES
	PHYTOCHEMICAL PROPERTIES
	BIOLOGICAL PROPERTIES
		Antidiabetic Activity
		Anticancer Activity
		Antioxidant Activity
		Anti-inflammatory Activity
		Male Sexual Functions
		Female Sexual Functions
		Anti-malarial Activity
		Antidepressant Activity
		Respiratory System Effects
		Anti-acanthamoeba Activity
		Antimicrobial Activity
		Miscellaneous Activities
	CONCLUDING REMARKS
	CONSENT FOR PUBLICATION
	CONFLICT OF INTEREST
	ACKNOWLEDGEMENTS
	REFERENCES
Clinical Aspects of Ashwagandha
	Pankaj Kumar Chaurasia1,*, Shashi Lata Bharati2,*, Sunil Kumar3 and Ashutosh Mani4
	INTRODUCTION
		Recent Research Updates
	CONCLUSION
	CONSENT FOR PUBLICATION
	CONFLICT OF INTEREST
	ACKNOWLEDGEMENT
	REFERENCES
Phytoconstituents, Biological Properties, and Health Benefits of Basil (Ocimum basilicum L.)
	Urvashi1,*, Ramandeep Kaur1 and Jyoti Gaba1
	INTRODUCTION
		Place of Origin (Habitat) and Distribution
		Historical Background
		Botanical Description and Taxonomical Classification
		Culinary and Cosmetic Uses
		Traditional Medicinal Uses
	PHYTOCHEMICAL COMPOSITION
	BIOLOGICAL PROPERTIES
		Antioxidant Activity
		Anticancer Activity
		Antidiabetic Activity
		Effects on gastrointestinal disorders- Antihyperlipidemic and Anti-Ulcerative Activity
		Hepato-protective Activity
		Dermatological and Cosmetic Properties
		Anti-inflammatory and Analgesic Activity
		Cardioprotective Activity
	CNS (CENTRAL NERVOUS SYSTEM) ACTIVITIES- SEDATIVE, HYPNOTIC AND ANTICONVULSANT
		Effect on Testicular Toxicity and Fertility
		Insecticidal Activity
		Antimicrobial Activity
	HEALTH-PROMOTING PROPERTIES
		Neurocognition
		Oral Health and Healing
		Skin Health
		Anti-inflammatory
		Anti-mutagenic
		Antiproliferative Activity
	MARKET REGIONAL OUTLOOK
	CONCLUSION
	CONSENT FOR PUBLICATION
	CONFLICT OF INTEREST
	ACKNOWLEDGEMENT
	REFERENCES
Phytochemistry and Pharmacology of Terminalia chebula: An Update
	Ojaskumar D. Agrawal1, 2 and Yogesh A. Kulkarni1,*
	INTRODUCTION
	METHODS
	BOTANY, MICROSCOPY, AND POWDER CHARACTERISTICS OF TERMINALIA CHEBULA
		Botanical Description, Distribution
		Taxonomical /Scientific Classification.
		Microscopic Description
		Powder Description
		Ecology and Distribution
	PHYTOCHEMICAL CONSTITUENTS
	BIOLOGICAL AND PHARMACOLOGICAL ACTIVITIES OF TERMINALIA CHEBULA
		Antioxidant Activity
		Anti-Ulcerogenic Activity
		Antibacterial Activity
		Antifungal Activity
		Antiviral Activity
		Cardio Protective Activity
		Cytoprotective Activity
		Radio Protective Activity
		Antidiabetic Activity
		Renoprotective Activity
		Anti-Inflammatory Activity
		Anti-Cancer Activity
		Anti-Typhoid Activity
		Anti-Caries Activity
		Wound Healing Activity
		Anti-Anaphylactic Action
	APPLICATION OF T. CHEBULA IN COSMETICS
	CONCLUSION
	CONSENT FOR PUBLICATION
	CONFLICT OF INTEREST
	ACKNOWLEDGEMENT
	REFERENCES
Role of Plants in Natural Medicinal Therapy
	G. S. Mulgund1 and Smita G. Bhat1,*
	INTRODUCTION
		Bioactivity of Herbal Medicine
		Current Status of Herbal Medicine
		Conservation of Medicinal Plants
	CONCLUSION
	CONSENT FOR PUBLICATION
	CONFLICT OF INTEREST
	ACKNOWLEDGEMENTS
	REFERENCES
Subject Index
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