The Biological Chemistry of Iron: A Look at the Metabolism of Iron and Its Subsequent Uses in Living Organisms Proceedings of the NATO Advanced Study Institute held at Edmonton, Alberta, Canada, August 13 – September 4, 1981

Front Matter....Pages i-xiii
Front Matter....Pages 1-1
Iron: An Element Well-Fitted for its Task?....Pages 3-12
Substitution and Electron Transfer in Metal Complexes—Particularly those of Iron....Pages 13-24
Oxidation States, Redox Potentials and Spin States....Pages 25-42
Front Matter....Pages 43-43
Ferritin — The Structure and Function of an Iron Storage Protein....Pages 45-61
Chemistry and Physiology of the Transferrins....Pages 63-83
Coordination Chemistry of the Siderophores and Recent Studies of Synthetic Analogues....Pages 85-105
Specificity of Siderophore Iron Uptake by Fungi....Pages 107-116
Iron Uptake and Intracellular Iron Distribution in Cultured Rat Heart Cells: Effects of Iron Chelators....Pages 117-124
Front Matter....Pages 125-125
NMR Studies of Low-Spin Cytochromes....Pages 127-141
Front Matter....Pages 143-143
Substitution and Electron Transfer Processes in Hemerythrin....Pages 145-160
The Environment of the Binuclear Iron Coordination Complex in Methemerythrin....Pages 161-175
Front Matter....Pages 177-177
Simple Iron-Sulfur Proteins: Methodology for Establishing the Type of Center....Pages 179-192
Catalysis by Highly Active 12Fe-12S Containing Hydrogenases....Pages 193-206
Hydrogenases: Physiology, Location and Relevance for Sulfate Reducing and Methane Forming Bacteria....Pages 207-222
Generation, Transport and Transfer of Low-Potential Reducing Equivalents in Nitrogenase Catalysis....Pages 223-240
Mössbauer and EPR Evidence on the Prosthetic Groups of the MoFe Protein....Pages 241-258
Front Matter....Pages 259-259
Magnetic Complexities in Porphinatoiron(III) Complexes....Pages 261-272
The Evaluation of Stabilization Energies (Empirical Resonance Energies) for Benzene, Porphine and [18] Annulene from Thermochemical Data, and from AB Initio Calculations....Pages 273-281
Models for Peroxidase and Cytochrome P-450 Enzymes....Pages 283-294
Structure and Spectra of Stable and Transient States and Mechanisms of Oxidation of Model Cytochrome P-450....Pages 295-312
Front Matter....Pages 259-259
Hemes of Hydroporphyrins....Pages 313-334
Front Matter....Pages 335-335
Peroxidases....Pages 337-355
The State of Protonation of the Proximal Histidyl Imidazole in Horseradish Peroxidase....Pages 357-373
Coordination Characteristics of Proximal Histidine of Plant Peroxidases and their Relevance to the Heme-Linked Ionization....Pages 375-389
Compounds I of Horseradish and Yeast Cytochrome C Peroxidases....Pages 391-403
Cytochrome P450: Structure and States....Pages 405-412
Cytochrome P450 as a Reductase and Oxene Transferase: Which is its Characteristic Function ?....Pages 413-425
Catalases and Iron-Porphyrin Model Systems: Roles of the Coordination Environment of Iron in Catalytic Mechanisms....Pages 427-438
The Structure of Beef Liver Catalase....Pages 439-458
The Subunits of Cytochrome C Oxidase....Pages 459-473
Extended x-ray absorption fine structure of the copper sites in Cytochrome C Oxidase....Pages 475-484
Back Matter....Pages 485-517