RNA Therapeutics

Front Matter ....Pages i-vii
 Computational Tools for Design of Selective Small Molecules Targeting RNA: From Small Molecule Microarrays to Chemical Similarity Searching  (Matthew G. Costales, Jessica L. Childs-Disney, Matthew D. Disney)....Pages 1-16
 A Modular Approach to the Discovery and Affinity Maturation of Sequence-Selective RNA-Binding Compounds  (Benjamin L. Miller)....Pages 17-45
 Structure-Based Discovery of Small Molecules Binding to RNA  (Thomas Wehler, Ruth Brenk)....Pages 47-77
 Approaches for the Discovery of Small Molecule Ligands Targeting microRNAs  (Daniel A. Lorenz, Amanda L. Garner)....Pages 79-110
 Viral RNA Targets and Their Small Molecule Ligands  (Thomas Hermann)....Pages 111-134
 Drugging Pre-mRNA Splicing  (Matthew G. Woll, Nikolai A. Naryshkin, Gary M. Karp)....Pages 135-176
 Targeting RNA G-Quadruplexes for Potential Therapeutic Applications  (Satyaprakash Pandey, Prachi Agarwala, Souvik Maiti)....Pages 177-206
 The Therapeutic Targeting of Long Noncoding RNA  (Caroline J. Woo)....Pages 207-235
 Messenger RNA as a Novel Therapeutic Approach  (Matthew G. Stanton, Kerry E. Murphy-Benenato)....Pages 237-253
Back Matter ....Pages 255-259