Rheumatology Board Review

Cover......Page 1
Title page......Page 5
Copyright page......Page 6
Contents......Page 7
List of Contributors......Page 9
Preface......Page 11
Epidemiology......Page 13
Clinical presentation......Page 14
Diagnosis......Page 15
Commonly involved joints......Page 16
Pathogenesis......Page 17
Physical examination......Page 18
Osteoarthritis treatment......Page 19
Etiologies......Page 24
Diagnosis......Page 28
Differential diagnosis for IE-HOA......Page 29
Clinical findings......Page 30
Radiologic findings (see also Chapter 11, Review of musculoskeletal radiology)......Page 31
Treatment......Page 32
Causes of early-onset gout......Page 33
Gout treatments......Page 34
Further reading......Page 37
2010 ACR/EULAR RA classification criteria......Page 39
What are they?......Page 40
Rheumatoid arthritis and cardiovascular disease......Page 41
Treatment advances in rheumatoid arthritis......Page 42
Abatacept – approved 2006......Page 43
Rituximab – approved 2006......Page 44
Tocilizumab – approved 2010......Page 45
Tuberculosis screening......Page 46
Key points in using vaccines in RA patients......Page 47
Drug toxicity monitoring......Page 48
B cell roles in SLE......Page 51
Rituximab......Page 53
Belimumab......Page 54
Additional therapies targeting B cells in SLE under investigation......Page 55
Classification criteria......Page 56
American College of Rheumatology guidelines for screening, treatment, and management of lupus nephritis......Page 57
Epidemiology......Page 67
Laboratory criteria......Page 68
The clinical spectrum of APS......Page 69
aCL antibodies and anti-β2GPI antibodies......Page 70
Who should be tested?......Page 71
Testing individuals on anticoagulant therapy......Page 72
Primary and secondary prevention of thrombosis in individuals with aPL......Page 73
Management of pregnancy outcomes in women with aPL......Page 75
Introduction......Page 77
Histology......Page 78
Etiology......Page 80
Clinical manifestations......Page 81
Head and neck area......Page 82
Abdomen and pelvic area......Page 84
Treatment......Page 87
Prognosis......Page 88
Common causes of myopathy......Page 89
Types of autoimmune-mediated myopathies......Page 90
Classification criteria......Page 91
Physical examination in AIM......Page 92
Laboratory findings in AIM......Page 94
Treatment......Page 99
Toxic and drug-induced myopathies......Page 100
Myopathy associated with hypothyroidism......Page 101
Juvenile idiopathic arthritis (JIA)......Page 103
Classification and diagnosis......Page 104
Treatment......Page 110
Prognosis......Page 114
Diagnosis......Page 115
Management......Page 116
Prognosis......Page 121
Diagnosis......Page 122
Etiology and pathogenesis......Page 123
Disease course......Page 124
Management......Page 125
Childhood vasculitis......Page 126
Henoch Schönlein purpura......Page 127
Kawasaki disease......Page 129
Outcome measures in pediatric rheumatology......Page 133
Validated measures in children......Page 134
General principles......Page 141
Approach to evaluating joint pain in HIV......Page 142
HIV-associated syndromes that mimic/overlap rheumatic syndromes......Page 144
Paraneoplastic syndromes......Page 149
Hematologic disorders......Page 150
Diabetes mellitus......Page 151
Thyroid disease......Page 152
Acromegaly......Page 153
Septic arthritis......Page 154
Viral arthritis......Page 156
Mycobacterial infections and arthropathy......Page 157
Fungi......Page 158
Diagnosis......Page 161
Therapeutic options......Page 164
Further reading......Page 168
Radiographic features of RA......Page 169
Radiographic features of psoriatic arthritis......Page 173
Radiographic features of ankylosing spondylitis......Page 176
Gout......Page 180
Calcium pyrophosphate disease......Page 181
Radiographic features of diffuse idiopathic skeletal hyperostosis (DISH)......Page 184
Radiographic features of sarcoidosis......Page 187
Neuropathic arthropathy (Charcot joint)......Page 188
Radiographic features of Paget’s disease of the bone......Page 190
Radiographic features of avascular necrosis (AVN)......Page 191
Radiographic features of osteoarthritis......Page 192
Epidemiologic study designs......Page 195
Common descriptors of data......Page 196
Disease frequency and risk factors......Page 198
Measurement error......Page 200
Basic statistical tests......Page 201
Further reading......Page 204
ANCA-associated vasculitides......Page 205
What are ANCAs?......Page 207
Treatment of AAV......Page 208
ANCA-positive vasculitis mimics......Page 210
Further reading......Page 211
Index......Page 213
Supplemental Images......Page 227