Research in Computational Molecular Biology: 14th Annual International Conference, RECOMB 2010, Lisbon, Portugal, April 25-28, 2010. Proceedings

Front Matter....Pages -
An Algorithmic Framework for Predicting Side-Effects of Drugs....Pages 1-14
SubMAP: Aligning Metabolic Pathways with Subnetwork Mappings....Pages 15-30
Admixture Aberration Analysis: Application to Mapping in Admixed Population Using Pooled DNA....Pages 31-49
Pathway-Based Functional Analysis of Metagenomes....Pages 50-64
Hierarchical Generative Biclustering for MicroRNA Expression Analysis....Pages 65-79
Subnetwork State Functions Define Dysregulated Subnetworks in Cancer....Pages 80-95
Proteome Coverage Prediction for Integrated Proteomics Datasets....Pages 96-109
Discovering Regulatory Overlapping RNA Transcripts....Pages 110-122
Alignment-Free Phylogenetic Reconstruction....Pages 123-137
Inference of Isoforms from Short Sequence Reads....Pages 138-157
The Clark Phase-able Sample Size Problem: Long-Range Phasing and Loss of Heterozygosity in GWAS....Pages 158-173
A New Algorithm for Improving the Resolution of Cryo-EM Density Maps....Pages 174-188
Towards Automated Structure-Based NMR Resonance Assignment....Pages 189-207
Gapped Spectral Dictionaries and Their Applications for Database Searches of Tandem Mass Spectra....Pages 208-232
naiveBayesCall: An Efficient Model-Based Base-Calling Algorithm for High-Throughput Sequencing....Pages 233-247
Extracting Between-Pathway Models from E-MAP Interactions Using Expected Graph Compression....Pages 248-262
Simultaneous Identification of Causal Genes and Dys-Regulated Pathways in Complex Diseases....Pages 263-280
Incremental Signaling Pathway Modeling by Data Integration....Pages 281-296
The Poisson Margin Test for Normalisation Free Significance Analysis of NGS Data....Pages 297-309
Compressing Genomic Sequence Fragments Using SlimGene ....Pages 310-324
On the Genealogy of Asexual Diploids....Pages 325-340
Genovo: De Novo Assembly for Metagenomes....Pages 341-356
MoGUL: Detecting Common Insertions and Deletions in a Population....Pages 357-368
Generalized Buneman Pruning for Inferring the Most Parsimonious Multi-state Phylogeny....Pages 369-383
Seed Design Framework for Mapping SOLiD Reads....Pages 384-396
Accurate Estimation of Expression Levels of Homologous Genes in RNA-seq Experiments....Pages 397-409
Cactus Graphs for Genome Comparisons....Pages 410-425
IDBA – A Practical Iterative de Bruijn Graph De Novo Assembler....Pages 426-440
Predicting Nucleosome Positioning Using Multiple Evidence Tracks....Pages 441-455
Dense Subgraphs with Restrictions and Applications to Gene Annotation Graphs....Pages 456-472
Time and Space Efficient RNA-RNA Interaction Prediction via Sparse Folding....Pages 473-490
HLA Type Inference via Haplotypes Identical by Descent....Pages 491-505
Algorithms for Detecting Significantly Mutated Pathways in Cancer....Pages 506-521
Leveraging Sequence Classification by Taxonomy-Based Multitask Learning....Pages 522-534
A Novel Abundance-Based Algorithm for Binning Metagenomic Sequences Using l -Tuples....Pages 535-549
A Markov Random Field Framework for Protein Side-Chain Resonance Assignment....Pages 550-570
Genomic DNA k -mer Spectra: Models and Modalities....Pages 571-571
Deciphering the Swine-Flu Pandemics of 1918 and 2009....Pages 572-573
Distinguishing Direct versus Indirect Transcription Factor-DNA Interactions....Pages 574-574
A Self-regulatory System of Interlinked Signaling Feedback Loops Controls Mouse Limb Patterning....Pages 575-576
Automated High-Dimensional Flow Cytometric Data Analysis....Pages 577-577
Discovering Transcriptional Modules by Combined Analysis of Expression Profiles and Regulatory Sequences....Pages 578-579
Back Matter....Pages -