Principles of Diabetes Mellitus

Front Matter....Pages i-xviii
Front Matter....Pages 1-1
The Main Events in the History of Diabetes Mellitus....Pages 3-16
Front Matter....Pages 17-17
Normal Glucose Homeostasis....Pages 19-35
Endocrine Pancreas....Pages 37-55
The Role of Incretins in Insulin Secretion....Pages 57-74
Cellular Mechanisms of Insulin Action....Pages 75-87
The Role of Brain in Glucose Metabolism....Pages 89-104
Front Matter....Pages 105-105
Diagnostic Criteria and Classification of Diabetes....Pages 107-115
Epidemiology....Pages 117-127
Diabetes in Culturally Diverse Populations: From Biology to Culture....Pages 129-144
Front Matter....Pages 145-145
Genetics of Type 2 Diabetes: From Candidate Genes to Genome-Wide Association Analysis....Pages 147-163
Rodent Models of Diabetes....Pages 165-178
Front Matter....Pages 179-179
Type 1 Diabetes Mellitus: Epidemiology, Genetics, Pathogenesis, and Clinical Manifestations....Pages 181-201
Type 2 Diabetes Mellitus: Epidemiology, Genetics, Pathogenesis, and Clinical Manifestations....Pages 203-220
Maturity-Onset Diabetes of the Young: Molecular Genetics, Clinical Manifestations, and Therapy....Pages 221-232
Diabetes in Pregnancy....Pages 233-244
Secondary Causes of Diabetes Mellitus....Pages 245-258
Syndromes of Extreme Insulin Resistance....Pages 259-277
Front Matter....Pages 279-279
Acute Hyperglycemic Syndromes: Diabetic Ketoacidosis and the Hyperosmolar State....Pages 281-295
Hypoglycemia in Diabetes Mellitus....Pages 297-312
Intake of Advanced Glycation Endproducts: Role in the Development of Diabetic Complications....Pages 313-330
Front Matter....Pages 279-279
Diabetic Retinopathy....Pages 331-346
Diabetic Nephropathy....Pages 347-355
Diabetic Neuropathy....Pages 357-370
Peripheral Vascular Disease in Diabetes....Pages 371-379
The Diabetic Foot....Pages 381-399
Male Sexual Dysfunction in Diabetes Mellitus....Pages 401-417
Gastrointestinal Manifestations of Diabetes....Pages 419-434
Dyslipidemia: Pathogenesis and Management....Pages 435-456
Dermatological Complications of Diabetes Mellitus; Allergy to Insulin and Oral Agents....Pages 457-471
Front Matter....Pages 473-473
Obesity – Genetics, Pathogenesis, Therapy....Pages 475-488
Hypertension....Pages 489-498
Coronary Artery Disease and Cardiomyopathy....Pages 499-513
Polycystic Ovary Syndrome....Pages 515-530
Insulin Resistance and the Metabolic Syndrome....Pages 531-555
Diabetes and Liver Disease....Pages 557-577
The Increased Risk of Cancer in Obesity and Type 2 Diabetes: Potential Mechanisms....Pages 579-599
Diabetes and Sleep Disorders....Pages 601-615
HIV Infection and Diabetes....Pages 617-642
Front Matter....Pages 643-643
Glycemic Goals....Pages 645-658
Behavioral and Educational Approaches to Diabetes Self-Management....Pages 659-675
Front Matter....Pages 643-643
Dietary Therapy of Diabetes Mellitus....Pages 677-686
Exercise in the Therapy of Diabetes Mellitus....Pages 687-708
Therapy of Type 1 Diabetes Mellitus....Pages 709-729
Treating Type 2 Diabetes Mellitus....Pages 731-747
Prevention of Microvascular Complications of Diabetes – General Overview....Pages 749-753
Psychiatric Care of the Patient with Diabetes....Pages 755-771
Management of Diabetes and Hyperglycemia in the Hospital Setting....Pages 773-786
The Future of Diabetes Therapy....Pages 787-800
Front Matter....Pages 801-801
Prevention of Type 1 Diabetes Mellitus....Pages 803-820
Prevention of Type 2 Diabetes Mellitus....Pages 821-832
Front Matter....Pages 833-833
Resources for Patients with Diabetes....Pages 835-844
Back Matter....Pages 845-887