Pathogenesis of Wound and Biomaterial-Associated Infections

Front Matter....Pages 1-11
Introduction....Pages 13-14
Healing, Scarring, and Contractures....Pages 15-23
The Effect of Staphylococcus aureus Bacteria and its Products on Wound Healing....Pages 25-34
Genetic Studies of Staphylococcus aureus Virulence Factors....Pages 35-46
Molecular Biology of Group A Streptococcal M Proteins....Pages 47-54
Fibronectin Binding Proteins from Staphylococcus aureus ....Pages 55-63
Fibrinogen-binding proteins from Staphylococcus aureus ....Pages 65-68
Osteomyelitis and Staphylococcal Adhesion....Pages 69-75
Phagocytosis of Bacteria by Endothelial Cells....Pages 77-85
Chromosomal DNA Analyses of Staphylococci....Pages 87-89
Microbiology of the Burn Compromised Patient....Pages 91-100
Immunomodulating Toxins and Tumor Necrosis Factors....Pages 101-105
Immunomodulators — Medicine for the 90-ies?....Pages 107-113
Pathogenesis of skin and wound infections. Animal models....Pages 115-119
Toxic Shock Syndrome from Surgical Infections....Pages 121-128
Fatty Acid Modifying Enzyme (FAME) and Staphylococcal Abscesses....Pages 129-137
Biosynthetic Dressing Materials and their Influence on Wound Healing and Infection....Pages 139-145
Clinical and Bacteriological Advantages in the Use of Occlusive Dressings....Pages 147-157
Development of a Semi-Synthetic Sugar Paste for Promoting Healing of Infected Wounds....Pages 159-162
Fibronectin-Substituted Gels for Treatment of Experimental Wound Infections in a Pig Model....Pages 163-168
Evaluation of Wound Healing by Quantifying of Bacteria and Computerized Image Analysis — A Pilot Study in Primary Health Care....Pages 169-171
Bacterial Affinity for Hydrophobic Ligands can be Employed in the Treatment of Infected Wounds in Patients....Pages 173-177
Krill and Other Enzymes in Enzymatic Wound Debridement....Pages 179-188
Computerized Wound Image Analysis....Pages 189-192
Biomaterial-Centered Infections: Microbial Adhesion versus Tissue Integration....Pages 193-216
Periimplant Infections of the Oral Cavity....Pages 217-220
Plasmaprotein Adsorption on Solid Surfaces. Some New Methods....Pages 221-232
Bacterial Cell-Surface Hydrophobicity....Pages 233-244
What Types of Bonds Are Responsible for the Adhesion of Bacteria and Viruses to Native and Artificial Surfaces?....Pages 245-253
Pathogenic Studies on Five Species of Coagulase-Negative Staphylococci: A Mouse Model with a Foreign Body Implant....Pages 255-263
Experimental Orthopaedic Infections....Pages 265-272
Microvascular Graft Infection in the Rat....Pages 273-278
Activity of Various Antibiotics on Production of Virulence Factors by Various Organisms....Pages 279-283
Structure and DNA-Sequence Analysis of the Staphylococcal Lantibiotics Epidermin and Gallidermin....Pages 285-292
Mupirocin: A New Antibiotic that Reduces Colonisation of Central Venous Cannulae by Skin Organisms....Pages 293-298
Coagulase-Negative Staphylococci....Pages 299-308
 Staphylococcus epidermidis — a Versatile Pathogen....Pages 309-315
Epidemiological markers of coagulase-negative staphylococci....Pages 317-323
Adherence of Staphylococcus aureus to Hep2 Monolayers and Fibronectin....Pages 325-327
Deep Infections Associated with Total Hip Arthroplasties Caused by Coagulase-Negative Staphylococci — Pathogenesis and Microbial Diagnosis....Pages 329-336
Fibronectin, Collagen and Vitronectin Binding of Coagulase-Negative Staphylococci....Pages 339-347
Role of Fibronectin on Staphylococcal Adherence to Metallic Surfaces Used as Models of Orthopaedic Devices....Pages 349-352
Serological Variation in the Fibronectin Binding to Protein-A-Deficient Mutants of Staphylococcus aureus ....Pages 353-360
Adherence of Staphylococci to Monolayers of Human Mesothelial Cells and their Removal by Phagocytes....Pages 361-365
Opsonic Requirements of Coagulase-Negative Staphylococci in Suspension and as a Biofilm: Implications for Host Defences....Pages 367-373
Microbiology of Infection in Prosthetic Devices....Pages 375-390
Prevention of Bacterial Growth Under Commercial Catheter Dressings....Pages 391-395
Possible Mechanisms of Damage Which Predispose Heart Valves to Endocarditis....Pages 397-407
Phenotypic Variation in the Pathogenesis of Experimental Endocarditis Caused by Staphylococcus epidermidis ....Pages 409-417
Pathogenesis of Experimental Prosthetic Endocarditis: Effect of Platelet-Associated Substances on Bacterial Survival and Growth....Pages 419-428
Fibrinolytic Treatment with Tissue-Type Plasminogen Activator (t-PA) of Streptococcus Sanguis Endocarditis....Pages 429-434
Improved Disinfection and Maintenance of Human Heart Valve Allografts....Pages 435-441
Hypothetical Model of Phenotypic Variation in Staphylococci....Pages 443-452
Phenotypic Changes in Staphylococcal Cell Surface Characteristics Associated with Growth in Human Peritoneal Dialysis Fluid....Pages 453-458
Slime Production by Coagulase Negative Staphylococci Causing Single and Recurrent Episodes of Peritonitis....Pages 459-464
Etiology and Microbial Pathogenesis of Acute and Late Onset Vascular Graft Infections....Pages 465-478
Experimental Bacteremic Vascular Graft Infection with Staphylococcus aureus . Comparative Colonization of Two Graft Materials and Prophylaxis of Late Infection....Pages 479-484
Pathogenesis of Infections Caused by Staphylococcus epidermidis ....Pages 485-491
Gentamicin Release In Vivo from Vacuum Mixed Low and High Viscosity Antibiotic Containing Bone Cement....Pages 493-500
The Development of Irgasan-Impregnated Intravenous Cannulae....Pages 501-506
The Pathogenesis of Catheter-related Infection in Central Venous Catheters using Gauze versus Transparent Dressings....Pages 507-517
In-Vitro Tests to Predict the Efficacy of Antibiotics in a Foreign-Body Infection Animal Model....Pages 519-523
Wound Contamination Correlates with Postsurgical Infection Rates: A New Assessment Technique....Pages 525-531
Capsular Polysaccharides of Staphylococcus aureus ....Pages 533-544
The Serodiagnosis of Deep Staphylococcal and Candida Infections....Pages 545-548
Concluding remarks....Pages 549-550
Back Matter....Pages 551-570