Opioid Peptides and Blood Pressure Control

Front Matter....Pages I-VIII
Endogenous Opioids and Cardiovascular Regulation: Introduction....Pages 1-2
Front Matter....Pages 3-3
Distribution of Opioid Peptides Functionally Related to the Cardiovascular System....Pages 5-12
Studies on Enkephalinergic Mechanisms in Cardiovascular Centers of the Medulla Oblongata of the Rat and their Interactions with Centrally Administered Neuropeptide Y....Pages 13-26
Multiplicity of Opioidergic Pathways Related to Cardiovascular Innervation: Differential Contribution of All Three Opioid Precursors....Pages 27-49
Front Matter....Pages 51-51
Opioids, Opiate Receptors, and Central Cardiovascular Regulation....Pages 53-61
Adrenergic-Opioid Interaction in the Brains System: Role in Cardiovascular Regulation....Pages 62-70
Influence of the Opioid System on Sympathetic Activity and the Renin-Aldosterone System in Healthy Males....Pages 71-82
Role of Leu-morphin, an Opioid Peptide, in the Central Regulation of Fluid Balance and Blood Pressure in Rats....Pages 83-89
Endogenous Opioids in the Dorsal Vagal Complex and Resting Cardiovascular Function in the Anesthetized Rat....Pages 90-97
Influence of Opiate Peptides on Blood Pressure Regulation and on Hypothalamic Blood Flow....Pages 98-102
Opioid Peptides in Human Adrenal Medulla: Their Role in the Modulation of Catecholamine Secretion....Pages 103-111
Cardiovascular effects of Neuropeptide Y in the Caudal Ventrolateral Medulla....Pages 112-116
Plasma Met-enkephalin and Cardiovascular Responses to Stress....Pages 117-126
Front Matter....Pages 127-127
Opioid Receptors in the Sympathetic Supply to Blood Vessels and the Heart....Pages 129-140
Interactions of Opioid Peptides and Adrenergic Agents in the Regulation of Blood Pressure....Pages 141-149
Effect of Opiate Receptor Blockade on the Cardiovascular and Plasma Noradrenaline Response to Intravenous Tyramine in Man....Pages 150-158
Effects of Mu- and Delta-Opiate Receptor Agonists on Systemic and Regional Hemodynamics in Conscious Rats....Pages 159-167
Retardment of Development of Hypertension in the Spontaneously Hypertensive Rat by Long-Term Kappa-Opioid Receptor Antagonism....Pages 168-173
Naltrexone Inhibits Alpha-Methyldopa-Induced Hypotension in a Dose-Dependent Manner....Pages 174-182
Effects of 17-alpha-Estradiol, a Possible Endogenous Opiate Antagonist, on Cardiovascular Responses in Conscious, Unrestrained Rats....Pages 183-189
Front Matter....Pages 127-127
Opioid Receptor Types at Noradrenergic Neurons and their Roles in Blood Pressure Regulation....Pages 190-205
Effects of Opioids on Plasma Levels of Immunoreactive Atrial Natriuretic Factor....Pages 206-211
Production by Systemic Enkephalin of Hemodynamic Effects by Afferent Modulation of Autonomic Nervous System Tone....Pages 212-218
Front Matter....Pages 219-219
Endogeneous Opioids in the Pathophysiology of Shock: Sites of Action, Autonomic Involvement, and Receptor Interactions....Pages 221-232
Endogenous Opioids and Blood Pressure in Man....Pages 233-235
Effects of Hemorrhagic Shock on Plasma Met-enkephalin, Vasopressin, Catecholamines, and Cardiovascular Functions in Intact and Adrenalectomized Dogs....Pages 236-246
Effect of Hypertension on the Response of Plasma Beta-Endorphin to the Cold Pressor Test....Pages 247-252
Normalization by Clonidine of Reduced Plasma Beta-endorphin and Leu-enkephalin Concentrations and Elevated Blood Pressure in Young Patients with Mild Essential Hypertension....Pages 253-259
Role of Opioids in the Pathophysiology of Hypertension....Pages 260-274
Effect of Low Dosage of Naloxone on Clonidine- Induced Changes in Blood Pressure, Catecholamines, Renin, and Aldosterone in Essential Hypertension....Pages 275-281
Effect of Lisinopril on Circulating Neuropeptides in Essential Hypertensive Patients....Pages 282-286
Endogenous Opioids and Reversal of Renovascular Hypertension....Pages 287-293
Comparison of Pain Threshold as Assessed by Tooth Pulp Stimulation in Normotensives with Different Hypertensive Hereditary Backgrounds and in Borderline and Established Hypertensives....Pages 294-298
Back Matter....Pages 299-300