Obesity and Lipotoxicity

Front Matter....Pages i-viii
The Definition and Prevalence of Obesity and Metabolic Syndrome....Pages 1-17
Circadian Rhythms in Diet-Induced Obesity....Pages 19-52
Eat and Death: Chronic Over-Eating....Pages 53-80
Obesity, Persistent Organic Pollutants and Related Health Problems....Pages 81-110
Human Protein Kinases and Obesity....Pages 111-134
Fat Cell and Fatty Acid Turnover in Obesity....Pages 135-160
Adipose Tissue Function and Expandability as Determinants of Lipotoxicity and the Metabolic Syndrome....Pages 161-196
What Is Lipotoxicity?....Pages 197-220
The Pathogenesis of Obesity-Associated Adipose Tissue Inflammation....Pages 221-245
Microbiota and Lipotoxicity....Pages 247-260
Endoplasmic Reticulum Stress and Obesity....Pages 261-276
Insulin Resistance, Obesity and Lipotoxicity....Pages 277-304
Adipose Tissue Hypoxia in Obesity and Its Impact on Preadipocytes and Macrophages: Hypoxia Hypothesis....Pages 305-326
Adipocyte-Macrophage Cross-Talk in Obesity....Pages 327-343
Endothelial Dysfunction in Obesity....Pages 345-379
Diet-Induced Obesity and the Mechanism of Leptin Resistance....Pages 381-397
Influence of Antioxidants on Leptin Metabolism and its Role in the Pathogenesis of Obesity....Pages 399-413
Adiponectin-Resistance in Obesity....Pages 415-441
Non-Alcoholic Fatty Liver Disease....Pages 443-467
Lipotoxicity-Related Hematological Disorders in Obesity....Pages 469-487
MicroRNA and Adipogenesis....Pages 489-509
The Interactions Between Kynurenine, Folate, Methionine and Pteridine Pathways in Obesity....Pages 511-527
Eligibility and Success Criteria for Bariatric/Metabolic Surgery....Pages 529-543
Does Bariatric Surgery Improve Obesity Associated Comorbid Conditions....Pages 545-570
Obesity-associated Breast Cancer: Analysis of risk factors....Pages 571-606
Lipotoxicity in Obesity: Benefit of Olive Oil....Pages 607-617
Back Matter....Pages 619-624