New Trends in Hepatology: The Proceedings of the Annual Meeting of the Italian National Programme on Liver Cirrhosis and Viral Hepatitis, San Miniato (Pisa), Italy, 7–9 January, 1996

Front Matter....Pages i-x
Front Matter....Pages 1-1
4-Hydroxy-Alkenals, Products of Lipid Peroxidation, as Signals for Biochemical Functions of Normal Cells....Pages 3-16
Oxidative Stress and Protein Kinase C Activity Modulation....Pages 17-23
Oxidative Damage in Chronic and Acute Liver Disease.....Pages 24-32
Chronic Ethanol Consumption Impairs Dolichol Levels and Glycosylation Processes in Rat Liver Microsomes and Golgi Apparatus....Pages 33-41
Compartmentation and Redox State of Thiols and Proteins During Acute Ethanol Intoxication in Rats....Pages 42-47
Possible Role of Ethanol-Derived Free Radicals in the Pathogenesis of Alcohol-Induced Liver Damage....Pages 48-55
Hepatic Iron Overload Induced by Phenylhydrazine: Release of Iron in a Free Form and DNA Damage....Pages 56-64
The Effects of Development of the MDR1 Phenotype on Cell Susceptibility to Undergoing Lipid Peroxidation and Ionizing Radiation.....Pages 65-73
Molecular and Cellular Aspects of Iron-Mediated Liver Toxicity....Pages 74-84
The Cellular and Molecular Basis of Liver Fibrogenesis....Pages 85-92
Proliferation of Hepatic Stellate Cells and Lipid Peroxidation: Changes Due to Polyphenols.....Pages 93-103
Reoxygenation Injury in Isolated Rat Hepatocytes....Pages 104-112
Oxidative Stress and Cell Damage Following Orthotopic Liver Transplantation.....Pages 113-121
The Genomic Response of Liver Cells to Post-Ischemic Reperfusion and Oxidative Stress.....Pages 122-129
Front Matter....Pages 131-131
Cytotoxic and Protective Effects of Bile Salts in Vitro ....Pages 133-141
Lamellar Bodies in Human Gallbladder Bile....Pages 142-148
Hepatocyte Lipid-Metabolic Interplays and the Cholesterol Secretion Process to Bile: Insights from Rat Studies.....Pages 149-157
Front Matter....Pages 159-159
Lipid Peroxidation and Hepatocarcinogenesis: γ-Glutamyl Transpeptidase-Dependent Oxidant Stress in Hepatic Preneoplastic Lesions and HEPG2 Human Hepatoma Cells....Pages 161-168
Antioxidant System in Hepatocellular Carcinoma....Pages 169-173
Loss of Heterozygosity of the Long Arm of Chromosome 16 in Hepatocellular Carcinoma on Liver Cirrhosis....Pages 174-182
Front Matter....Pages 159-159
Potential Molecular Mechanisms of Viral Liver Carcinogenesis....Pages 183-196
Prevalence of Wild-Type and Variant Transcripts of Liver Estrogen Receptors in Chronic Liver Disease....Pages 197-203
Front Matter....Pages 205-205
Molecular Biology of HCV: Implications in Epidemiology and Diagnosis of Infection....Pages 207-216
Cell-mediated Immune Response in Hepatitis C Virus (HCV) Infection: Are Different Strategies Adopted by HCV and Hepatitis B Virus to Persist?....Pages 217-226
The Epidemiological and Clinical Aspects of Hepatitis C in Italy....Pages 227-233
Diagnostic Evaluation of Patients with Chronic HCV Infection....Pages 234-243
Correlation Between Hepatitis C Virus RNA Levels in Serum, Liver and Peripheral Blood Mononuclear Cells and Severity of Liver Disease in Chronic Hepatitis C Patients....Pages 244-250
Hepatitis C Virus Lymphotropism and Possible Pathogenetic Implications.....Pages 251-259
HCV-Induced Cryoglobulinemic Vasculitis: Pathogenesis and Therapeutic Implications....Pages 260-272
Front Matter....Pages 273-273
Cirrhosis Associated Congestive Gastropathy....Pages 275-285
Treatment of Ascites in Cirrhosis....Pages 286-295
Spectral EEG Monitoring of Hepatic Encephalopathy.....Pages 296-305
Interaction Between Non Steroidal Antiinflammatory Drugs and Interferon-α System: Mechanisms and Basis for the Clinical Use in the Treatment of Chronic Viral Hepatitis.....Pages 306-314
Pharmacological Treatment of Primary Biliary Cirrhosis....Pages 315-325
Back Matter....Pages 327-336