Modulation by Molecular Interactions: Current Topics in Cellular Regulation

Content: 
Front Matter
Page iii

Copyright page
Page iv

Contributors
Pages ix-xiv

Foreword
Page xv
Arthur Kornberg

Preface
Page xvii
P. Boon Chock, Ann Ginsburg, Rodney L. Levine, Shmuel Shaltiel

Thressa C. Stadtman
Pages xviii-xix

Earl R. Stadtman
Pages xx-xxi

The LDL Receptor and HMG-CoA Reductase — Two Membrane Molecules That Regulate Cholesterol Homeostasis
Pages 3-15
Michael S. Brown, Joseph L. Goldstein

The Cellular Entry of EGF and Transferrin: A Problem in Intracellular Sorting
Pages 17-25
Ira Pastan, John Hanover, Mark Willingham

Receptor-Mediated Transport of Acid Hydrolases to Lysosomes
Pages 27-38
William S. Sly

Diagnostic and Therapeutic Applications of Sphingolipid Hydrolyzing Enzymes
Pages 39-50
Roscoe O. Brady

Platelet-Derived Growth Factor: Structure, Function, and Roles in Normal and Transformed Cells
Pages 51-64
Thomas F. Deuel, Benton D. Tong, Jung S. Huang

Regulation of Glutamine Synthetase in Cultured 3T3-L1 Adipocytes by Insulin, Hydrocortisone, and Cyclic AMP
Pages 65-78
Richard E. Miller, Douglas M. Burns

Scrapie Prions, Brain Amyloid, and Senile Dementia
Pages 79-95
Stanley B. Prusiner

Coupled Ionic and Enzymatic Regulation of Sperm Behavior
Pages 97-113
Bennett M. Shapiro, Robert W. Schackmann, Robert M. Tombes, Theodossia Kazazoglou

Regulation of Cell Interactions during Skeletal Muscle Development
Pages 115-126
David C. Turner, Dorothy Gibralter

Regulation of the Immune Response in Man by a Cascade of Interactive T Lymphocytes
Pages 127-135
Nahid Mohagheghpour, Nitin K. Damle, Edgar G. Engleman

From Membrane to Molecule with the lac Permease of Escherichia coli
Pages 137-148
H.R. Kaback

Glutamine Synthetase from Pseudomonos fluorescens: A Tool for Studying Changes in Cell Permeability and Enzyme Regulation
Pages 149-161
J.-M. Meyer

Modulation of Polar Lipid Composition by Aliphatic Chain Unsaturation in Bacteria
Pages 163-174
Howard Goldfine

On Conformational Changes in the Regulatory Enzyme Aspartate Transcarbamoylase
Pages 177-190
Robert E. Cohen, Jefferson Foote, H.K. Schachman

Active-Site Ligand Binding and Subunit Interactions in Glutamine Synthetase from Escherichia coli
Pages 191-206
Michael R. Maurizi, Ann Ginsburg

Biophysical Studies of Escherichia coli Glutamine Synthetase
Pages 207-219
Joseph J. Villafranca, Stephen C. Ransom, Esther J. Gibbs

The Regulation of Actin and Myosin by ATP
Pages 221-232
Edward D. Korn

Change in NAD+/NADH Content of S-Adenosyl-L-Homocysteine Hydrolase upon NAD+ Reversible Inactivation by cAMP and 2′-Deoxyadenosine
Pages 233-245
Robert J. Hohman, Michel Véron, Marie-Christine Guitton

Effectors of Rat Lung cGMP Binding Protein-Phosphodiesterase
Pages 247-262
Sharron H. Francis

Thermostabilization of Bacillus caldolyticus Glutamine Synthetase by Intrinsic and Extrinsic Factors
Pages 263-280
Frederick C. Wedler, David J. Merkler

The Role of Pyridoxal 5′-Phosphate in Phosphorylase Catalysis
Pages 281-294
Helmut W. Klein, Ernst J.M. Helmreich

Bioregulation of Binding and Dynamics: The Cytochrome P-450CAM Model
Pages 295-309
I.C. Gunsalus, P.K. Bhattacharyya, K. Suhara

Fatty Acid Synthase: Elementary Steps in Catalysis and Regulation
Pages 311-324
Gordon G. Hammes

Multienzyme Complexes of Mammalian Aminoacyl-tRNA Synthetases
Pages 325-335
David C.H. Yang, J. Victor Garcia, Yvonne D. Johnson, Samir Wahab

The Pyruvate Dehydrogenase Complex in Dictyostelium discoideum
Pages 337-346
Margaret Husta Butler, Galen P. Mell, Barbara E. Wright

Pathway of 5-Aminovalerate Degradation by Clostridium aminovalericum
Pages 349-354
H.A. Barker

Inorganic Pyrophosphate and Polyphosphates as Sources of Energy
Pages 355-369
Harland G. Wood

The Role of Pyridine Nucleotides in Regulating Cellular Metabolism
Pages 371-381
Nathan O. Kaplan

The Fall and Rise of Cellular Glutathione Levels: Enzyme-Based Approaches
Pages 383-394
Alton Meister

The Effects of Protein or Amino Acid Intake on the Nitrogen Balance and Antitumor Activity of Glutaminase Treatment
Pages 395-402
John S. Holcenberg, C. Lawrence Kien

On the Regulation of Deoxyribonucleotide Synthesis
Pages 403-409
Peter Reichard, Björn Nicander

Completion of the Degradation Scheme for Nicotinic Acid by Clostridium barkeri
Pages 411-418
Hermann Eggerer

Mechanisms of Exogenous Purine Nucleotide Utilization in Bacillus cereus
Pages 419-432
Pier Luigi Ipata, Francesco Sgarrella, Maria Grazia Tozzi

Pyrimidine Nucleoside-Catabolizing Enzymes in Escherichia coli B
Pages 433-443
Giulio Magni, Alberto Vita, Adolfo Amici

Recent Biochemical and Genetic Studies on the Amino Acid Biosynthetic Pathway of the Aspartate Family in Escherichia coli
Pages 447-454
Georges N. Cohen, Michel Véron, Mario M. Zakin

Regulation of Antibiotic Resistance in Bacteria: The Chloramphenicol Acetyltransferase System
Pages 455-468
William V. Shaw, Daniel G. Brenner, Iain A. Murray

An in Vitro System to Measure Gene Expression Based on Dipeptide Synthesis
Pages 469-484
Herbert Weissbach

Regulation of Enzymes under Nitrogen Control in Pseudomonas aeruginosa
Pages 485-490
Chris van der Drift, Dick B.J. Anssen

Catabolism and Nitrogen Control in Escherichia coli
Pages 491-502
Mary Anne Berberich

Regulation of Gene Expression of Translation Components in Escherichia coli: Initiation Factors and Aminoacyl tRNA Synthetases
Pages 503-520
Marianne Grunberg-Manago, John B.W. Hershey, Jacqueline A. Plumbridge, Christine Sacerdot, Mathias Springer, Guy Fayat, Patrick Lestienne, Jean-Francois Mayaux, Sylvain Blanquet

Regulatory Features of Spore Development in Bacillus subtilis
Pages 521-529
Jekisiel Szulmajster

Bacterial Gene Expression and Biotechnology
Pages 531-542
Hsiang-fu Kung, Mlloslav Moublik, Veeraswamy Manne, Shigeko Yamazaki, Emilio Garcia

Index
Pages 543-549

Cumulative Contributors Index
Pages 551-555

Contents of Recent Volumes
Pages 557-565