Illustrated Handbook of Rheumatic and Musculo-Skeletal Diseases

Preface
Acknowledgements
Contents
Abbreviations
1 Examination of the Musculoskeletal System
	1.1 Introduction
	1.2 Clinical Examination
	1.3 Imaging Modalities
	References and Further Reading
2 Autoimmune Rheumatic Diseases: Pathophysiology and Laboratory Tests
	2.1 Introduction
	2.2 Non-specific Laboratory Markers
	2.3 Specific Laboratory Markers in Rheumatology
	2.4 Autoantibodies
	2.5 Elements of Pathophysiology
	References and Further Reading
3 Disease Metrics and Activity Scores
	3.1 Introduction
	3.2 DAS-28—Disease Activity Score 28 (Rheumatoid Arthritis)
	3.3 SDAI/CDAI—Simplified/Clinical Disease Activity Index (Rheumatoid Arthritis)
	3.4 ASDAS—Ankylosing Spondylitis Disease Activity Score
	3.5 BASDAI—Bath Ankylosing Spondylitis Disease Activity Index
	3.6 DAPSA and DAPSA 28 (Psoriatic Arthritis)
	3.7 ESSPRI—EULAR Sjögren’s Syndrome Disease Activity Index
	3.8 Five-Factor Score (for Systemic Necrotizing Vasculitides)
	3.9 Summary of the Scores Used in Rheumatology
	References
4 Musculoskeletal Ultrasound in Rheumatology
	4.1 History
	4.2 Introduction
	4.3 Application of Ultrasound in Rheumatology
	4.4 Elementary Lesions by OMERACT Study Group
	4.5 OMERACT Semiquantitative Scale for Joint Assessment
	4.6 EULAR Standardization of the Ultrasound Examination
	References and Further Reading
5 Rheumatoid Arthritis
	5.1 Introduction
	5.2 Epidemiology
	5.3 Risk Factors
	5.4 Signs and Symptoms
	5.5 Diagnosis and Differential Diagnosis
	5.6 Diagnostic Modalities
	5.7 Pathophysiology
	5.8 Management
	References and Further Reading
6 Sjögren’s Syndrome
	6.1 Introduction
	6.2 Epidemiology
	6.3 Aetiopathogenesis
	6.4 Classification Criteria
	6.5 Signs and Symptoms
	6.6 Diagnosis and Differential Diagnosis
	6.7 Management
	References and Further Reading
7 Spondyloarthropathies
	7.1 Introduction
	7.2 Evolution of the Classification Criteria in SpA
	7.3 SpA Pathophysiology
	7.4 Imaging
	7.5 Management
	References and Further Reading
8 Ankylosing Spondylitis
	8.1 Introduction
	8.2 Epidemiology
	8.3 Aetiopathogenesis
	8.4 Classification Criteria
	8.5 Signs and Symptoms
	8.6 Differential Diagnosis
	8.7 Diagnostic Modalities
	8.8 Radiographic Changes
	8.9 Management
	References and Further Reading
9 Psoriatic Arthritis
	9.1 Introduction
	9.2 Epidemiology
	9.3 Signs and Symptoms
	9.4 Diagnostic Modalities
	9.5 Management
	References and Further Reading
10 Systemic Lupus Erythematosus
	10.1 Introduction
	10.2 Aetiology and Pathogenesis
	10.3 Epidemiology
	10.4 Classification Criteria
	10.5 Signs and Symptoms
	10.6 Differential Diagnosis
	10.7 Diagnostic Modalities
	10.8 Management
	References and Further Reading
11 Scleroderma
	11.1 Introduction
	11.2 Epidemiology
	11.3 Aetiopathogenesis
	11.4 Classification Criteria
	11.5 Signs and Symptoms
	11.6 Differential Diagnosis
	11.7 Diagnostic Modalities
	11.8 Management
	References and Further Reading
12 Inflammatory Myopathies
	12.1 Introduction
	12.2 Aetiopathogenesis
	12.3 Epidemiology
	12.4 Signs and Symptoms
	12.5 Diagnostic Modalities
	12.6 Management
	References and Further Reading
13 Vasculitides
	13.1 Introduction
	13.2 Aetiology and Pathogenesis
	13.3 Epidemiology
	13.4 Nomenclature and Classification
	13.5 Signs and Symptoms
	13.6 Diagnostic Modalities
	13.7 Management
	References and Further Reading
14 Osteoarthritis
	14.1 Introduction
	14.2 Epidemiology
	14.3 Aetiopathogenesis
	14.4 Signs and Symptoms
	14.5 Diagnostic Modalities
	14.6 Management
	References and Further Reading
15 Crystal Arthropathies
	15.1 Introduction
	15.2 Epidemiology
	15.3 Aetiopathogenesis
	15.4 Classification Criteria
	15.5 Signs and Symptoms
	15.6 Diagnostic Modalities
	15.7 Management
	References and Further Reading
16 Osteoporosis
	16.1 Introduction
	16.2 Osteoporosis Types
	16.3 Aetiology
	16.4 Diagnostic Modalities
	16.5 Management
	References and Further Reading
17 Sarcoidosis
	17.1 Introduction
	17.2 Epidemiology
	17.3 Aetiopathogenesis
	17.4 Clinical Manifestations
	17.5 Diagnostic Approach
	17.6 Management
	References
18 Miscellaneous Conditions
	18.1 Relapsing Polychondritis
		18.1.1 Introduction
		18.1.2 Epidemiology
		18.1.3 Clinical Manifestations
		18.1.4 RP Associated Disorders
		18.1.5 Pathogenesis
		18.1.6 Diagnosis
		18.1.7 Management
	18.2 Diffuse Idiopathic Skeletal Hyperostosis (DISH)
		18.2.1 Introduction
		18.2.2 Epidemiology
		18.2.3 Clinical Manifestations
		18.2.4 Differential Diagnosis
		18.2.5 Treatment
	References and Further Reading
19 Adverse Drug Reactions in Rheumatology
	19.1 Introduction
	19.2 Corticosteroids
	19.3 Cyclosporine
	19.4 Methotrexate
	19.5 Hydroxychloroquine
	19.6 Biologics
	19.7 Others
	References and Further Reading