Fluid Dynamics as a Localizing Factor for Atherosclerosis: The Proceedings of a Symposium Held at Heidelberg, FRG, June 18–20, 1982

Front Matter....Pages I-X
Opening Comments....Pages 1-2
Fluid Dynamic Approaches to Atherosclerosis....Pages 3-8
A Fluid-Dynamicist’s and a Physiologist’s Look at Arterial Flow and Arteriosclerosis....Pages 9-25
The Case for Fluid Dynamics as a Localizing Factor in Atherogenesis....Pages 26-37
Flow and Atherogenesis in the Human Carotid Bifurcation....Pages 38-45
Pulsating Flow in Distensible Models of Vascular Branches....Pages 46-50
Coronary Artery Geometry and Its Fluid Mechanical Implications....Pages 51-59
Flow Patterns in Model and Natural Branching Vessels....Pages 60-70
Geometric Effects on the Hemodynamic Environment of the Arterial Wall: A Basis for Geometric Risk Factors?....Pages 71-78
The Drainage of Transmural Flow and the Consequences of Its Insufficiency....Pages 79-86
Fluid Mechanical Factors in Macromolecular Transport by the Arterial Wall....Pages 87-90
The Role of Hydrodynamic Factors in Platelet Activation and Thrombotic Events: The Effects of Shear Stress of Short Duration....Pages 91-102
Microrheology of Thrombocyte Deposition: Effect of Stimulation, Flow Direction, and Red Cells....Pages 103-115
The Localization of Transient Subendothelial Water-Filled Blisters in the in Situ Rabbit Aorta as a Result of Reduction in Pressure....Pages 116-128
Influence of Convection and Vasoactive Agents on the Mass Transport Properties of the Arterial Wall....Pages 129-134
Haemodynamic Influences on Platelets in Haemostasis and Thrombosis....Pages 135-140
Effects of Antihypertensive Drugs and Blood Velocity....Pages 141-144
General Properties of Endothelial Cells....Pages 145-158
The Endothelium as a Mediating Factor in Transport Across the Arterial Wall....Pages 159-167
Morphology and Fluid-Dynamics of Endothelial Cells at the Site of Vascular Bifurcation....Pages 168-172
Location and Morphology of Hypertensive Lesions in Coronary Arteries of Dogs....Pages 173-181
Response of Vascular Endothelium to Unsteady Fluid Shear Stress in Vitro....Pages 182-187
Injury at the Vascular Surface....Pages 188-199
Cellular Participation in Atherogenesis: Selected Facets of Endothelium, Smooth Muscle, and the Peripheral Blood Monocyte....Pages 200-207
Evidence that High Flow Velocity and Endothelial Disruption Are Not the Principal Factors in Experimental Plaque Localization....Pages 208-211
Localization of Early Atherosclerotic Lesions in Carotid and Coronary Bifurcations in Humans — A Bifurcation of the High Shear Stress Hypothesis....Pages 212-215
Quantitative Arterial Wall Morphology....Pages 216-226
Back Matter....Pages 227-232