Differential Diagnosis in Orthopaedic Oncology

Cover
Differential Diagnosis in Orthopaedic
Oncology
Contents
Preface
Acknowledgments
Radiologic and Pathologic Approach to Bone Tumors
	Radiology
		Radiography
			Site of the Lesion
			Borders of the Lesion
			Type of Bone Destruction
			Periosteal Response
			Type of Matrix
			Soft Tissue Mass
		Scintigraphy (Radionuclide Bone Scan)
		Positron Emission Tomography
		Computed Tomography and Magnetic Resonance Imaging
	Pathology
		Basic Techniques and Decalcification
		Special Stains and Enzyme Histochemistry
		Immunohistochemistry
			Antibodies Against Intermediate Filaments
			Antibodies Against Hematopoietic and Lymphoid Cells
			Antibodies Against Vascular Antigens
			Antibodies Against Muscle Antigens
			Other Useful Antibodies in Bone Tumor Pathology
		Electron Microscopy
		Genetics in Bone Tumors
			Flow Cytometry
			Cytogenetics
			Molecular Cytogenetics
		Bone-Forming
(Osteogenic) Lesions
Bone-Forming
(Osteogenic) Lesions
	Benign Lesions
		Osteoma
		Enostosis (Bone Island)
		Osteoid Osteoma
		Osteoblastoma
	Malignant Tumors
		Osteosarcomas
		Primary
Osteosarcomas
		A. Intraosseous Osteosarcomas
			Intramedullary (Conventional) Osteosarcoma
			Malignant Fibrous Histiocytoma–like
(Fibrohistiocytic) Osteosarcoma
			Giant Cell–Rich Osteosarcoma
			Small Cell Osteosarcoma
			Telangiectatic Osteosarcoma
			Low-Grade (Well-Differentiated) Central Osteosarcoma
			Gnathic Osteosarcoma
			Multicentric (Multifocal) Osteosarcoma
			Osteosarcomas with Unusual Clinical Presentation
		B. Intracortical Osteosarcomas
		C. Surface Osteosarcomas
			Parosteal Osteosarcoma
			Dedifferentiated Parosteal Osteosarcoma
			Periosteal Osteosarcoma
			High-Grade Surface Osteosarcoma
		D. Soft Tissue (Extraskeletal) Osteosarcomas
		Secondary Osteosarcomas
			Paget Sarcoma
			Osteosarcoma Arising in Fibrous Dysplasia
			Osteosarcoma Arising in Bone Infarct
			Postirradiation Osteosarcoma
Cartilage(Chondrogenic)
Lesions
	Benign Lesions
		Enchondroma
		Periosteal (Juxtacortical) Chondroma
		Enchondromatosis, Ollier Disease, and Maffucci Syndrome
		Soft Tissue Chondroma
		Osteochondroma (Osteocartilaginous Exostosis)
		Multiple Hereditary Osteochondromata (Hereditary Osteochondromatosis)
		Chondroblastoma (Codman Tumor)
		Chondromyxoid Fibroma
		Synovial (Osteo)chondromatosis
	Malignant Tumors
		Chondrosarcomas
		Primary Chondrosarcomas
			Conventional Medullary Chondrosarcoma
			Clear Cell Chondrosarcoma
			Mesenchymal Chondrosarcoma
			Myxoid Chondrosarcoma
			Dedifferentiated Chondrosarcoma
			Periosteal (Juxtacortical) Chondrosarcoma
			Synovial Chondrosarcoma
			Extraskeletal (Soft Tissue) Chondrosarcoma
		Secondary Chondrosarcomas
Fibrogenic, Fibroosseous, and
Fibrohistiocytic Lesions
	Benign Lesions
		Fibrous Cortical Defect and Nonossifying Fibroma
		Benign Fibrous Histiocytoma
		Periosteal Desmoid
		Fibrous Dysplasia
			Monostotic Fibrous Dysplasia
			Polyostotic Fibrous Dysplasia
		Osteofibrous Dysplasia (Kempson-Campanacci Lesion)
		Desmoplastic Fibroma
	Malignant Tumors
		Fibrosarcoma and Malignant Fibrous Histiocytoma
Round Cell Lesions
	Benign Lesions
		Langerhans Cell Histiocytosis (Eosinophilic Granuloma)
	Malignant Tumors
		Ewing Sarcoma
		Malignant Lymphoma
			Non-Hodgkin Lymphoma
			Hodgkin Lymphoma
		Multiple Myeloma (Plasmacytoma)
Vascular Lesions
	Benign Lesions
		Intraosseous Hemangioma
		Synovial Hemangioma
		Cystic Angiomatosis
		Lymphangioma and Lymphangiomatosis
		Glomus Tumor, Glomangioma, and Glomangiomyoma
	Malignant Tumors
		Epithelioid Hemangioendothelioma
		Angiosarcoma
		Hemangiopericytoma
Miscellaneous Tumors And Tumor-like Lesions
	Benign Lesions
		Giant Cell Tumor
			Malignant Giant Cell Tumor
		Simple Bone Cyst
		Aneurysmal Bone Cyst
		Solid Variant of Aneurysmal Bone Cyst
		Intraosseous Lipoma
		Fibrocartilaginous Mesenchymoma
	Malignant Tumors
		Adamantinoma of Long Bones
		Chordoma
		Leiomyosarcoma of Bone
Metastases
	Osseous Metastases
		SOLITARY METASTASIS
			Lytic Metastasis
			Sclerotic Metastasis
			Mixed Metastasis
		MULTIPLE METASTASES
			Lytic Metastases
			Sclerotic Metastases
		CORTICAL METASTASES
Tumors and Tumor-like Lesions of the Joints
	Benign Lesions
		Synovial (Osteo)chondromatosis
		Pigmented Villonodular Synovitis
		Localized Pigmented Nodular Tenosynovitis [Pigmented Giant Cell Tumor of the Synovium or the (Localized) Giant Cell Tumor of the Tendon Sheath]
		Synovial Hemangioma
		Lipoma Arborescens
	Malignant Tumors
		Synovial Sarcoma
		Synovial Chondrosarcoma
Subject Index