Diabetes and Cardiovascular Disease: Etiology, Treatment, and Outcomes

Front Matter....Pages i-xi
Type 2 Diabetes in Youth: A New Epidemic....Pages 1-5
Undiagnosed Diabetes Burden and Significance in the Canadian Population....Pages 7-10
Genes, Environment and Diabetes in Canadian Aboriginal Communities....Pages 11-20
Diabetes in Sub-Saharan Africa....Pages 21-26
Coronary Heart Disease and Risk Factors in Asian Indians....Pages 27-34
The Plasma Glucose Level - A Continuous Risk Factor for Vascular Disease in Both Diabetic and Non-Diabetic People....Pages 35-39
Modified Lipoproteins and Cardiovascular Risk....Pages 41-48
Advances in Lipid-Lowering Therapy in Atherosclerosis....Pages 49-58
Homocysteine as a Risk Factor in Cardiovascular Disease....Pages 59-64
Endothelial Integrity and Repair....Pages 65-74
Molecular Mechanisms of Endothelial Dysfunction in the Diabetic Heart....Pages 75-86
A Study of Vascular Wound Healing in a Rabbit Model of Type I Diabetes....Pages 87-96
Endothelins in the Microvasculature and Heart in Diabetes....Pages 97-108
Diabetes and Endothelial Function: Implications for Coronary Angioplasty....Pages 109-114
The Effect of Hypertension in Diabetes....Pages 115-117
The Diabetic Hypertensive (or Hypertensive Diabetic) - A Compelling Need to Optimize Blood Pressure....Pages 119-125
Left Ventricular Diastolic Dysfunction in Diabetic or Hypertensive Subjects: Role of Collagen Alterations....Pages 127-132
Alterations in the Vascular Actions of Insulin in the Pathogenesis of Insulin Resistance and Hypertension....Pages 133-142
Cardiac Hypertrophy in Diabetes Patients With and Without Hypertension: Effects of Troglitazone, a Novel Antidiabetic Drug, on Diastolic Function....Pages 143-148
Cost and Benefits of Blood Pressure Monitoring and Control....Pages 149-154
Malonyl Coa Control of Fatty Acid Oxidation in the Diabetic Rat Heart....Pages 155-165
Alterations in 1,2-Diacylglycerols and Ceramides in Diabetic Rat Heart....Pages 167-173
Regulation of Myocardial Phospholipid N-Methylation By Insulin and Diabetes....Pages 175-181
Reduction of Phosphatidylinositol -4,5-Bisphosphate mass in Heart Sarcolemma during Diabetic Cardiomyopathy....Pages 183-190
Tumor Necrosis Factor-α, Sphingomyelinase and Ceramides Activate Tyrosine Kinase, P21ras and Phosphatidylinositol 3-Kinase: Implications for Glucose Transport and Insulin Resistance....Pages 191-200
Antioxidants, Free Radical Stress and Diabetes....Pages 201-211
Oxidative Stress and Functional Deficit in Diabetic Cardiomyopathy....Pages 213-220
Ketosis and the Generation of Oxygen Radicals in Diabetes Mellitus....Pages 221-227
Effect of Diabetes Mellitus on Hemodynamic and Cardiometabolic Correlates in Experimental Myocardial Infarction....Pages 229-240
Cardiac Function in Perfused Hearts from Diabetic Mice....Pages 241-245
Mg 2+ -Dependent Atpase Activity in Cardiac Myofibrils from The Insulin-Resistant JCR:La-Cp Rat....Pages 247-252
Cyclic Nucleotide Phosphodiesterase Families in Intracellular Signaling and Diabetes....Pages 253-261
Alterations in G-Protein-Linked Signal Transduction in Vascular Smooth Muscle in Diabetes....Pages 263-271
Mechanism of HDL Lowering In Insulin Resistant States....Pages 273-277
Insulin Treatment Post Myocardial Infarction: The Digami Study....Pages 279-284
Response to Ischemia and Endogenous Myocardial Protection in the Diabetic Heart....Pages 285-293
Type 2 Diabetes: Pharmacological Intervention in an Animal Model....Pages 295-302
The Diabetic Heart and Cardiac Glycosides....Pages 303-310
Hyperglycemia-Induced Protein Kinase Signaling Pathways in Vascular Smooth Muscle Cells: Implications in The Pathogenesis of Vascular Dysfunction in Diabetes....Pages 311-318
Regulation of Myocardial and Skeletal Muscle Na,K-ATPase in Diabetes Mellitus in Humans and Animals....Pages 319-322
Food Strategies For Diabetes And Heart Health....Pages 323-329
The Atherosclerosis Reversal Clinic: The Way of the Future....Pages 331-335
Lipid Clinics/Cardiovascular Risk Reduction Clinics Current State and Future Consideration....Pages 337-347
Amputation Prevention and Rehabilitation in Diabetes....Pages 349-358
Laboratory Testing in Diabetes Mellitus....Pages 359-366
Diabetes and Cardiovascular Disease Brian O’Connor North Shore Health Region Vancouver....Pages 367-371
Prevalence of Cardiovascular Risk Factors in Canadians with Diabetes Mellitus....Pages 373-380
G7 Project Promoting Heart Health....Pages 381-384
Canadian Heart Health Initiative: Research Review....Pages 385-387
Putting Policy Into Action....Pages 389-392
National and International Strategies to Prevent Obesity and Diabetes....Pages 393-400
The Diabetes Council of Canada (DCC): Coordinating National Diabetes Strategies....Pages 401-403
The Federal Government and Diabetes an Incremental Process....Pages 405-409
Back Matter....Pages 411-415