Cochlear Mechanisms: Structure, Function, and Models

Front Matter....Pages i-xii
Front Matter....Pages 1-1
Structural Organization of the Mammalian Auditory Hair Cells in Relation to Micromechanics....Pages 3-10
Observations on the Cytoskeleton and Related Structures of Mammalian Cochlear Hair Cells....Pages 11-20
A Comparative Study of Actin Filaments in Cochlear Hair Cells: Outer Hair Cells in the Apex of the Guinea Pig Cochlea Contain a Unique Ultrastructural Feature....Pages 21-28
The Lateral Walls of Inner and Outer Hair Cells....Pages 29-35
Tip-Link Organization in Relation to the Structure and Orientation of Stereovillar Bundles....Pages 37-44
Front Matter....Pages 45-45
Hair Cell Mechanics Controls the Dynamic Behaviour of the Lateral Line Cupula....Pages 47-55
Aminoglycoside Antibiotics and Lectins Cause Irreversible Increases in the Stiffness of Cochlear Hair-Cell Stereocilia....Pages 57-65
Mechanical Analysis of Hair Cell Microstructure and Motility....Pages 67-74
A Model for Bidirectional Transduction in Outer Hair Cells....Pages 75-82
A Three-Degree-of-Freedom Active Micromechanical Model of the Cochlear Partition....Pages 83-92
Outer Hair Cells Possess Acetylcholine Receptors and Produce Motile Responses in the Organ of Corti....Pages 93-98
Mechano-Electrical Transduction in Turtle Hair Cells....Pages 99-105
Transducer Motor Coupling in Cochlear Outer Hair Cells....Pages 107-114
Structure of the Cortical Cytoskeleton Outer Hair Cells from the Guinea Pig Organ of Corti....Pages 115-116
Gating Compliance, a Reduction in Hair-Bundle Stiffness Associated with the Gating of Transduction Channels in Hair Cells from the Bullfrog’s Sacculus....Pages 117-123
Simultaneous Recording of Fluctuations of Hair-Bundle Deflection and Intracellular Voltage in Saccular Hair Cells....Pages 125-133
Micromechanical Movements of Chick Sensory Hair Bundles to Sinusoidal Stimuli....Pages 135-142
Micromechanical Basis of High-Frequency Tuning in the Bobtail Lizard....Pages 143-151
Mechanical Coupling between Inner and Outer Hair Cells in the Mammalian Cochlea....Pages 153-160
Front Matter....Pages 161-161
Phase Reversal in OHC Response at High Sound Intensities....Pages 163-168
Front Matter....Pages 161-161
Outer Hair Cell Receptor Current and its Effect on Cochlear Mechanics....Pages 169-176
Saturation of Receptor Currents Accounts for Two-Tone Suppression....Pages 177-188
Components of the Membrane Current in Guinea-Pig Inner Hair Cells....Pages 189-195
Cochlear Nonlinearities Reflected in Inner Hair Cell Responses....Pages 197-204
Asymmetries in Motile Responses of Outer Hair Cells in Simulated in Vivo Conditions....Pages 205-206
Round Window Cochlear Microphonic and Atrophy of Short and Middle Stereocilia on Outer Hair Cells in Hydropic Cochleas in Guinea Pigs....Pages 207-215
Postnatal Developement of the Cochlea in Horseshoe Bats....Pages 217-223
On the Origin of Interspecific Differences in Auditory Susceptibility....Pages 225-233
Response Properties of Turtle Auditory Afferent Nerve Fibers: Evidence for a High Order Tuning Mechanism....Pages 235-240
Cochlear Filtering: A View Seen through the Temporal Discharge Patterns of Single Cochlear Nerve Fibres....Pages 241-250
Cochlear Nonlinearities Implied by the Differences between Transient Onsets and Offsets to a Tone Burst....Pages 251-257
“Peak-Splitting”: Intensity Effects in Cochlear Afferent Responses to Low Frequency Tones....Pages 259-267
Front Matter....Pages 269-269
Discussion Session I....Pages 271-295
Front Matter....Pages 297-297
Historical Background to the Proposal, 40 Years Ago, of an Active Model for Cochlear Frequency Analysis....Pages 299-305
CM and OAE Changes Following Transient Efferent Excitation....Pages 307-314
Effect of Visual Selective Attention on Otoacoustic Emissions....Pages 315-321
Tracking and Interpretive Models of the Active-Nonlinear Cochlear Response during Reversible Changes Induced by Aspirin Consumption....Pages 323-330
Analysis and Influence of Lidocaine on Evoked Otoacoustic Emissions from Tinnitus Sufferers....Pages 331-339
An Electrical Correlate of Spontaneous Otoacoustic Emissions in a Frog, a Preliminary Report....Pages 341-347
Otoacoustic Evidence for Nonlinear Behaviour in Frogs’ Hearing: Suppression but No Distortion Products....Pages 349-358
Front Matter....Pages 297-297
Otoacoustic Emissions and Cochlear Travelling Waves....Pages 359-366
Front Matter....Pages 367-367
Nonlinear Interactions in the Mechanical Response of the Cochlea to Two-Tone Stimuli....Pages 369-375
Determinants of High-frequency Sensitivity in the Bird....Pages 377-385
Mechanical Response of the Outer Hair Cell Region of an Isolated Guinea Pig Cochlea in Vitro....Pages 387-392
Front Matter....Pages 393-393
Power-Law Nonlinearities: A Review of Some Less Familiar Properties....Pages 395-403
Distortion Product Responses of Saturating Nonlinearities....Pages 405-412
Front Matter....Pages 413-413
Realistic Basilar Membrane Tuning Does Not Require Active Processes....Pages 415-423
A Model of Peripheral Auditory Preprocessing....Pages 425-436
On the Stability of Cochlear Mechanical Models....Pages 437-444
Time-Domain Solutions for 1D, 2D and 3D Cochlear Models....Pages 445-452
Is Basilar Membrane Tuning the Same as Neural Tuning -- Where Do We Stand?....Pages 453-463
On the Nature of Cochlear Resonance....Pages 465-474
Front Matter....Pages 475-475
Discussion Session II....Pages 477-491
Back Matter....Pages 493-506