Circulating Nucleic Acids in Plasma and Serum: Proceedings of the 6th international conference on circulating nucleic acids in plasma and serum held on 9-11 November 2009 in Hong Kong.

Front Matter....Pages i-xx
Front Matter....Pages 1-1
Current Developments in Circulating Nucleic Acids in Plasma and Serum....Pages 3-12
Front Matter....Pages 13-13
Reflections on a Life of CNAPS: From Circulating DNA to the Virtosome....Pages 15-20
Circulating Tumor-Related DNA Alterations as Prostate Cancer Biomarkers....Pages 21-27
Parallel Tagged 454 Sequencing for the Characterization of Circulating DNA....Pages 29-33
Advanced Analysis of Human Plasma Circulating DNA Sequences Produced by Parallel Tagged Sequencing on the 454 Platform....Pages 35-40
Concentration and Distribution of Single-Copy β -Actin Gene and LINE-1 Repetitive Elements in Blood of Lung Cancer Patients....Pages 41-45
Plasma DNA Methylation Analysis in Predicting Short-Term Recurrence of Surgical Patients with Non-small Cell Lung Cancer (NSCLC)....Pages 47-55
Blood Based Methylated DNA and Tumor-Specific Protein Analysis in Gastric Cancer Diagnostics....Pages 57-61
Increase in Circulating MicroRNA Levels in Blood of Ovarian Cancer Patients....Pages 63-71
The Course of Circulating Nucleosomes in Liver Cancer Patients Undergoing Transarterial Chemoembolization Therapy....Pages 73-77
Presence of Nucleosomes in Cerebrospinal Fluid of Glioblastoma Patients – Potential for Therapy Monitoring....Pages 79-84
Circulating Nucleosomes and DNAse in Breast Cancer Patients During Neoadjuvant Chemotherapy....Pages 85-89
Circulating Nucleosomes in Cancer Patients with Liver Metastases Undergoing Selective Internal Radiation Therapy Using Yttrium-90 Labelled Microspheres....Pages 91-95
H3K9me3/H4K20me3 Ratio in Circulating Nucleosomes as Potential Biomarker for Colorectal Cancer....Pages 97-103
Functionality of CNAPS in Cancer: The Theory of Genometastasis....Pages 105-108
Front Matter....Pages 109-109
Circulating Fetal DNA/RNA in Maternal Plasma for Aneuploidy Detection....Pages 111-124
A “Fluid-Agnostic” Approach to Analysis of Fetal and Neonatal Developmental Gene Expression....Pages 125-132
Non-invasive Prenatal Diagnosis: An Epigenetic Approach to the Detection of Common Fetal Chromosome Disorders by Analysis of Maternal Blood Samples....Pages 133-142
Comparative Study of Extracellular DNA by FISH....Pages 143-146
An Additional Pre-amplification Step for the Early Determination of Fetal RHD from Maternal Plasma....Pages 147-151
Front Matter....Pages 109-109
The Correlation of Circulating Cell-Free DNA, Cell-Free Fetal DNA and MicroRNA 325 Levels to Clinical Characteristics and Laboratory Parameters in Pre-eclampsia....Pages 153-156
Front Matter....Pages 157-157
Comparison of Plasma Cell-Free DNA Levels with Gene Expression Profiles of Peripheral Blood Cells During Haemodialysis....Pages 159-163
Low-Molecular-Weight DNA of Blood Plasma as an Indicator of Pathological Processes....Pages 165-170
The Clinical Significance of Plasma DNA Quantification for Quake Trauma Patients....Pages 171-182
Front Matter....Pages 183-183
Methylated Cell-Free DNA In Vitro and In Vivo....Pages 185-194
Circadian Rhythmicity and Clearance of Cell-Free DNA in Human Plasma....Pages 195-198
Fragments of Cell-Free DNA (cfDNA) Enhance Transcription Activity in Human Mesenchymal Stem Cells (hMSCs) and Inhibit Their In Vitro Differentiation....Pages 199-205
Cell-Surface-Bound DNA Inhibits Poly(I:C)-Activated IL-6 and IL-8 Production in Human Primary Endothelial Cells and Fibroblasts....Pages 207-211
Accumulating Fragments of Extracellular DNA (ecDNA) Influence Rat Primary Cerebellum Granule Cell Culture....Pages 213-218
Cell Free DNA (cfDNA) Influences Nitric Oxide and ros Levels in Human Endothelial Cells....Pages 219-223
Development of the Adaptive Response and Bystander Effect Induced by Low-Dose Ionising Radiation in Human Mesenchymal Stem Cells....Pages 225-231
Extracellular RNA as Regulators of Cellular Processes....Pages 233-237
Microvesicles Circulating in Plasma of Rats Contain DNA: Are These Small Vesicles a Main Source of Cell-Free DNA in Plasma?....Pages 239-244
Front Matter....Pages 245-245
Rapid Isolation and Detection of Cell Free Circulating DNA and Other Disease Biomarkers Directly from Whole Blood....Pages 247-257
Yields of Viral and Circulating Cell-Free Nucleic Acids Using the QIAamp ® Circulating Nucleic Acid Kit....Pages 259-268
Comparison of Nucleosomes and Quantitative PCR Using Diverse DNA Isolation Methods....Pages 269-273
MicroRNA Analysis in the Spinal Fluid of Alzheimer Patients: A Methodological Feasibility Study....Pages 275-282
Back Matter....Pages 283-285