Biochemistry and Function of Phagocytes

Front Matter....Pages i-xvi
Three Types of Granule Formed in Guinea Pig and Rat Heterophil Granulocytes....Pages 1-7
Leucocyte Activation and the Assessment of Leucocyte Locomotion and Chemotaxis....Pages 9-17
Distribution of Actin-Binding Protein and Myosin in Neutrophils During Chemotaxis and Phagocytosis....Pages 19-28
Interaction between Neutrophils and Mediators of Inflammation....Pages 29-37
A Short Transient Increase in Cyclic Adenosine 3′, 5′-Monophosphate Levels of Neutrophil Granulocytes Following Exposure to Chemotactic Factors....Pages 39-48
Neutrophil Migration and Orientation Under Agarose: Findings in Patients with the Immotile Cilia Syndrome and Effects of Cytochalasin B and Vinblastine....Pages 49-59
A Differential Responsiveness of In Vitro Differentiating Mononuclear Phagocytes from Bone Marrows of Normal and Inflamed Mice to Lymphokines and Poly I•Poly C....Pages 61-70
The Oxygen-Dependent Antibody-Dependent Cell-Mediated Cytotoxicity of Human Monocytes and Neutrophils....Pages 71-84
Macrophage Activation for Tumor Cytotoxicity: Reactivity of Peritoneal and Bone Marrow Macrophages....Pages 85-97
Cytotoxicity on Tumor Cells of Human Macrophages: Functional Status of Tumor-Associated Effector Cells....Pages 99-108
Studies on the Recognition of Xenogeneic Cells by Nonimmune Macrophages. II. Separate Signals Triggered Cytostasis and Cytolysis....Pages 109-118
Genetic Aspects of Macrophage Activation for Tumor Cytotoxicity....Pages 119-128
O 2 -Independent Killing of Gram-Negative Bacteria by Intact Granulocytes. The Role of a Potent Bactericidal Membrane-Perturbing Protein....Pages 129-137
The Extracellular Stimulation of Intracellular Killing by Phagocytes....Pages 139-149
Molecular Mechanism of the Bactericidal Action of Myeloperoxidase-H 2 O 2 -Chloride....Pages 151-160
The Role of the Cell Membrane in the Killing Mechanism of Polymorphonuclear Leucocytes (PMN)....Pages 161-165
Leptospires Macrophage Interactions....Pages 167-174
Relationship between the Enhanced Oxidative Metabolism and the Enhanced Microbicidal Activity of Activated Macrophages....Pages 175-177
Release of Superoxide Anion and Enhanced Candidacidal Activity as a Manifestation of Macrophage Activation: Studies with Muramyl Dipeptide....Pages 179-187
Killing of Leishmania Donovani Amastigotes by Murine Macrophages....Pages 189-198
Selective Depression of Phagocytes Intracellular Killing Activity....Pages 199-206
Modulation of the Inflammatory Response by the Neutrophil Myeloperoxidase System....Pages 207-216
Elastase Secretion by Mouse Peritoneal Macrophages: Effects of Rifampin and Corticosteroids....Pages 217-223
Synthesis and Release of Factor Increasing Monocytopoiesis (FIM) by Macrophages....Pages 225-232
Biochemical and Biological Characteristics of Leucocyte Proteinase Inhibitors....Pages 233-245
Oxidative Damage to Lysosomal Enzymes in Human Phagocytosing Neutrophils....Pages 247-257
The Release of Platelet-Activating Factor during Phagocytosis by Polymorphonuclear Neutrophils and Monocytes....Pages 259-268
The Secretion of Lysosomal Enzymes by Human Polymorphonuclear Leucocytes (PMN) and Its Modulation by Serum Complement....Pages 269-276
The Bovine Neutrophil: Separation and Partial Characterization of Plasma Membrane and Cytoplasmic Granules....Pages 277-281
The Respiratory Burst of Phagocytic Cells: Facts and Problems....Pages 283-322
Discrepancies in the Oxygen Balance of Whole Human Neutrophils and Neutrophil Homogenates....Pages 323-334
Neutrophil Activation Studied Using Two Indirect Probes of Membrane Potential Which Respond by Different Fluorescence Mechanisms....Pages 335-349
Formation of Superoxide Anions and Hydrogen Peroxide by Polymorphonuclear Leukocytes Stimulated with Cytochalasin....Pages 351-360
Hydrogen Peroxide Production in A Cell-Free System: Evidence for the Involvement of A Chain Reaction....Pages 361-370
The Respiratory Burst in Human Polymorphonuclear Leucocytes Stimulated by Particles....Pages 371-381
Stimulation of the Hexose Monophosphate Shunt Activity in Human Polymorphonuclear Leukocytes....Pages 383-392
The Nature and Function of the Microbicidal Oxidase System of Neutrophils....Pages 393-400
Chemiluminescence and the Study of Phagocyte Redox Metabolism....Pages 401-409
An Alternative Mechanism for the Production of Hydroxyl Radicals by Stimulated Neutrophils....Pages 411-421
Superoxide Dismutases and the Oxidative Burst in Human Blood Polymorphonuclear Leukocytes....Pages 423-427
Role of Serine Proteases in Superoxide Production by Human Neutrophils, Monocytes and Basophils....Pages 429-440
Release of the Membrane-Calcium and Its Relation to the Superoxide Formation by Polymorphonuclear Leukocytes....Pages 441-451
ATP-Driven Ca 2+ Pump Activity of Macrophage and Neutrophil Plasma Membrane....Pages 453-461
Ca 2+ Transport and Surface Membrane ATPase in Macrophages....Pages 463-472
Effect of Ionophores on Lymphocyte Cellular Metabolism....Pages 473-480
Peroxidatic Activity Distinct from Myeloperoxidase in Human Monocytes Cultured in Vitro and in Alveolar Macrophages....Pages 481-489
Characterization of the Peroxidase in Human Eosinophils....Pages 491-499
Stimulation or Activation of Eosinophils in Vivo during Eosinophilia: Possible Role of Arachidonic Acid Metabolism....Pages 501-508
Platelet Leukocyte Interactions II in-Vivo Correction of Chediak-Higashi Leukocyte Function with Serotonin or Normal Platelets....Pages 509-518
Physicochemical Surface Changes on Phagocytic Cells during Differentiation in Relation to Chemotaxis and Phagocytosis....Pages 519-530
Mechanism of Hexose Transport in Human Polymorphonuclear Leukocytes....Pages 531-538
Tuftsin and Substance P as Modulators of Phagocyte Functions....Pages 539-547
The Effect of Hyaluronic Acid on Neutrophil Function in Vitro and in Vivo....Pages 549-558
Expression of Fc And C3b Receptors and Intracellular Distribution of Bacteria in Rat Macrophages....Pages 559-565
Monocyte Activation by Immune Complexes of Patients with SLE....Pages 567-573
Nucleotide Concentrations in Leucocytes and Their Use in Controlling the Quality of Cell Preparations....Pages 575-582
Resting and Stimulated Chemiluminescence of Polymorphonuclear Leukocytes: A Clinical Approach....Pages 583-590
Deficient Phagocytosis Secondary to Breakdown of Opsonic Factors in Infected Exudates....Pages 591-601
Congenital and Acquired Lactoferrin Deficiencies in Neutrophils....Pages 603-610
Functional and Metabolic Abnormalities of Diabetic Monocytes....Pages 611-620
Enzymatic Deficiency in Monocytes from Patients with Chronic Granulomatous Disease....Pages 621-628
Use and Results of Neutrophil Function Testing in Pediatric Immunology....Pages 629-635
The Effect of Influenza Virus on Oxygen-Dependent Metabolism of Human Neutrophils....Pages 637-645
Chronic Granulomatous Disease, Kx Negative Neutrophils and Linkage with Xg ....Pages 647-654
Round Table on the Clinical Application of Leucocyte Function Tests....Pages 655-658
Back Matter....Pages 659-682
....Pages 683-699