Advances in Endogenous and Exogenous Opioids. Proceedings of the International Narcotic Research Conference (Satellite Symposium of the 8th International Congress of Pharmacology) Held in Kyoto, Japan on July 26–30, 1981

Content: 
Front Matter, Page iii
Copyright, Page iv
Organizing Committee of the INRC Meeting for 1981 “Advances in Endogenous and Exogenous Opioids”, Page v
Executive Committee of the International Narcotic Research Conference (INRC), Page v
Preface, Page vii, Eric J. SIMON, Hiroshi TAKAGI
Acknowledgements, Page ix
List of Participants, Pages xi-xiv
THE INTERACTION OF OPIOID PEPTIDES AND ALKALOID OPIATES WITH μ-, δ- AND κ-BINDING SITES, Pages 2-4, S.J. Paterson, J. Magnan, A. Tavani, H.W. Kosterlitz
CHARACTERIZATION OF NOVEL OPIATE BINDING SITES SELECTIVE FOR BENZOMORPHAN DRUGS, Pages 5-8, K-J. Chang, P. Cuatrecasas
BIOCHEMICAL EVIDENCE FOR KAPPA AND SIGMA OPIATE RECEPTORS, Pages 9-11, S.R. Zukin, A. Margolis, R.S. Zukin
CHARACTERIZATION OF DYNORPHIN RECEPTOR SPECIFICITY IN THE GUINEA PIG ILEUM, Pages 12-14, Charles Chavkin, Avram Goldstein
OPIATE RECEPTORS IN THE GUINEA-PIG ILEAL MUCOSA, Pages 15-17, R.J. Miller, J.F. Kachur, M. Field
OPIATE BINDING SITES IN THE LUMBO-SACRAL SPINAL CORD FROM VARIOUS SPECIES, Pages 18-20, C. Gouardères, B. Attali, Y. Audigier, J. Cros
EFFECTS OF OPIOID PEPTIDES AND KAPPA-RECEPTOR AGONISTS ON IN VITRO ISOLATED PREPARATIONS, Pages 21-23, T. Oka, K. Negishi, M. Suda
MULTIPLE BENZOMORPHAN BINDING SITES IN A CLONAL CELL LINE, Pages 24-26, R.E. West Jr., R.W. McLawhon, G. Dawson, R.J. Miller
MORPHINE AND OXYMORPHONE ACT AS PARTIAL AGONISTS ON THE FIELD STIMULATED RAT VAS DEFERENS, Pages 27-29, C.S. Liao, A.R. Day, R.J. Freer
SPECIFIC OPIATE BINDING SITES IN HUMAN PLACENTA, Pages 30-32, A. Valette, G. Pontonnier, G. Porthé, Y. Audigier, J. Cros
MULTIPLE BINDING SITES FOR 3H-ETHYLKETOCYCLAZOCINE ON THE LUMBO-SACRAL PORTION OF THE GUINEA-PIG SPINAL CORD, Pages 33-35, B. Attali, C. Gouardères, Y. Audigier, J. Cros
DIFFERENTIAL INTERACTIONS OF DYNORPHIN(1–13), β-ENDORPHIN, AND ENKEPHALIN-RELATED PEPTIDES AT μ AND δ SITES IN DIFFERENT BRAIN REGIONS, Pages 36-38, William A. Hewlett, Jack D. Barchas, Hudd Akil
DIFFERENTIAL EFFECTS OF ISOMERS OF OPIOID ANTAGONISTS UPON μ-, κ- and δ AGONIST ANALGESIA: COMPARISON WITH OXOTREMORINE, Pages 39-41, M.M. Ben-Sreti, R.D.E. Sewell
POTENCIES OF “MU” AND “KAPPA” AGONISTS ON SMOOTH MUSCLE PREPARATIONS RELATIVE TO DISPLACEMENT OF 3H-ETORPHINE IN ISOLATED RAT BRAIN NEURAL MEMBRANES, Pages 42-44, C.B. Smith, F. Medzihradsky
COMPARISON OF 3H-ETORPHINE AND 3H-DIPRENORPHINE RECEPTOR BINDING IN VIVO AND IN VITRO, Pages 45-47, M. Kurowski, J. Rosenbaum, D.C. Perry, W. Sadée
TENTATIVE IDENTIFICATION OF HIGH AFFINITY OPIOID BINDING SITES IN THE PEDAL GANGLIA OF THE MARINE MUSSEL Mytilus edulis, Pages 48-50, G.B. Stefano, R.S. Zukin, R.M. Kream
OPIOID RECEPTORS ON RAT MAST CELLS, Pages 51-53, Y. Yamasaki, O. Shimamura, H. Ijichi
MECHANISMS OF SUPERSENSITIVITY IN THE ENKEPHALINERGIC SYSTEM, Pages 54-56, E.L. Gardner, R.S. Zukin, A.R. Gintzler
POSTNATAL DEVELOPMENT OF OPIOID MECHANISMS IN RAT VAS DEFERENS, Pages 57-59, A.Z. Rónai, I.P. Berzétei, J. Kurgyis
DEVELOPMENTAL DIFFERENCES OF METHIONINE ENKEPHALIN AND NALOXONE BINDING SITES IN REGIONS OF RAT BRAIN, Pages 60-62, D. Tsang
μ, δ AND κ OPIATE RECEPTORS: INTERCONVERTIBLE FORMS OF THE SAME RECEPTOR, Pages 63-65, R. Quirion, W.D. Bowen, C.B. Pert
CHARACTERIZATION OF SOLUBILIZED ACTIVE OPIATE RECEPTORS FROM TOAD BRAIN, Pages 68-70, E.J. Simon, J.M. Hiller, T. Gioannini, R.D. Howells, U.T. Ruegg
MULTIPLE ETORPHINE BINDING PROTEINS FROM BRAIN, Pages 71-73, W.L. Byrne, W.A. Klee
DIFFERENCES BETWEEN THE OPATE RECEPTOR AND THE ENKEPHALIN RECEPTOR IN RAT BRAIN, Pages 74-76, N. Ogawa, Y. Yamawaki, H. Kuroda, I. Nukina, T. Ofuji
PROPERTIES OF THE SOLUBILIZED OPIATE RECEPTOR FROM HUMAN PLACENTA, Pages 77-79, Mahmoud S. Ahmed
ISOLATION OF AN OPIATE RECEPTOR AND THE EFFECT OF MEMBRANE LIPIDS ON ISOLATED RECEPTOR BINDING, Pages 80-82, Tae Mook Cho, Horace H. Loh, Chiyuki Yamato
PHOSPHATIDYL INOSITOL AS A BINDING COMPONENT OF OPIOID RECEPTOR, Pages 83-85, J. Hasegawa, M. Niwa, M. Nozaki, H. Fujimura, S. Nagaoka
SELECTIVITY OF OPIATE AND OPIOID PEPTIDE INTERACTION WITH CEREBROSIDE SULFATE, Pages 86-88, C. Yamato, T.M. Cho, H.H. Loh, N. Ling
IRREVERSIBLE PHOTOACTIVATION OF THE OPIATE RECEPTORS IN THE GUINEA-PIG ILEUM BY SOME ENKEPHALIN DERIVATIVES, Pages 89-91, U. Nagai, Y. Kudo, K. Sato, N. Taki
EFFECTS OF SULFHYDRYL-PROTECTING REAGENTS ON OPIOID RECEPTOR BINDING SITE(S), Pages 92-94, M. Niwa, J. Hasegawa, M. Nozaki, H. Fujimura
STIMULATION AND DESENSITIZATION OF cGMP FORMATION BY OPIOID AGONISTS IN CLONED NEUROBLASTOMA CELLS, Pages 95-97, G.J. Gwynn, E. Costa
ASCORBATE SUPPRESSES OPIATE INDUCED COMPENSATORY INCREASE IN CYCLIC AMP LEVELS IN NEUROBLASTOMA X GLIOMA HYBRID CELLS, Pages 98-101, Shail K. Sharma, Navin C. Khanna
A CASE AGAINST RECEPTOR OCCUPANCY AS THE SOLE DETERMINANT IN THE OPIATE REGULATION OF ADENYLATE CYCLASE ACTIVITY IN NEUROBLASTOMA CELLS, Pages 102-105, P.Y. Law, D.S. Horn, H.H. Loh
INCREASE IN PLASMA CYCLIC NUCLEOTIDE LEVELS INDUCED BY MORPHINE IN MALE MICE, Pages 106-108, T. Muraki, T. Nakadate, R. Kato
STRUCTURAL ORGANIZATION OF THE CORTICOTROPIN-β-LIPOTROPIN PRECURSOR GENE, Pages 110-112, Shigetada Nakanishi, Shosaku Numa
BIOSYNTHESIS AND MATURATION OF PRO-OPIOMELANOCORTIN, Pages 113-115, N.G. Seidah, N. Larivière, G. Boileau, F. Gossard, M. Chrétien
MULTIPLE FORMS OF BETA-ENDORPHIN (βE) IN PITUITARY AND BRAIN: EFFECT OF STRESS, Pages 116-118, H. Akil, Y. Ueda, H-L. Lin, J.W. Lewis, J.M. Walker, H. Shiomi, J.C. Liebeskind, S.J. Watson
CALCITONIN-LIKE PEPTIDE IN PRO-OPIOCORTIN: FUNCTIONAL ASPECTS, Pages 119-121, D.L. Margules, J.J. Flynn, C.W. Cooper
EFFECT OF MORPHINE OR ALCOHOL TREATMENT ON THE BIOSYNTHESIS OF β-ENDORPHIN BY THE NEUROINTERMEDIATE LOBE, Pages 122-124, C. Gianoulakis, N. Woo, H. Kalant, J.N. Drouin, N.G. Seidah, M. Chrétien
MEMBRANES OF BOVINE CHROMAFFIN GRANULES CONTAIN ENKEPHALIN PRECURSORS LARGER THAN 100,000 DALTONS, Pages 125-127, D.R. Liston, A. Artola, G. Patey, J. Rossier, M.P. Roisin, J.P. Henry
PROENKEPHALIN AND INTERMEDIATES IN THE BIOSYNTHESIS OF ENKEPHALINS, Pages 128-130, Sadao Kimura
“BIG” ENKEPHALINS FROM BOVINE ADRENOMEDULLARY GLAND, Pages 131-133, K. Mizuno, N. Minamino, K. Kangawa, H. Matsuo
CONVERSION OF MET-ENKEPHALIN-Arg6-Phe7 TO MET-ENKEPHALIN BY DIPEPTIDYL CARBOXYPEPTIDASE, Pages 134-136, H.Y.T. Yang, E. Majane, E. Costa
SEARCH FOR MORPHINE-ANTAGONISTIC AGENTS IN HUMAN CSF AND BRAIN, Pages 138-141, A. Wahlstrom, L. Terenius
H-ENDORPHIN, A NOVEL ENDOGENOUS OPIOID WITH UNCONVENTIONAL NALOXONE INTERACTIONS, Pages 142-144, Y. Sarne, B.A. Weissman, G. Urca
ISOLATION AND IDENTIFICATION OF TWO NEW PEPTIDES RELATED TO β-ENDORPHIN, Pages 145-148, D.G. Smyth, C.C. Smith, S. Zakarian
ISOLATION OF DYNORPHIN-LIKE PEPTIDE FROM GUT EXTRACT, Pages 149-151, S. Tachibana, K. Araki, S. Ohya, S. Yoshida
SUBSTANTIAL AMOUNTS OF IMMUNOREACTIVE BAM-12P AND BAM-22P ARE PRESENT IN BOVINE ADRENAL MEDULLA BUT NOT IN THE BRAIN, Pages 152-154, V. Höllt, C. Grimm, I. Haarmann, B.R. Seizinger, A. Herz
DETECTION OF α-N-ACETYL β-ENDORPHINS IN PITUITARY BY SPECIFIC ANTIBODIES, Pages 155-157, Eckard Weber, Christopher J. Evans, Jack D. Barchas, Jaw-Kang Chang
REGIONAL DISTRIBUTION OF IMMUNOREACTIVE “BIG” LEU-ENKEPHALINS IN BRAIN AND PITUITARY, Pages 160-162, N. Minamino, Y. Hayashi, K. Kitamura, H. Matsuo, K. Kangawa
ANATOMICAL AND BIOCHEMICAL STUDIES OF DYNORPHIN, Pages 163-165, S. Watson, H. Akil, A. Goldstein
β-ENDORPHIN IN THE BRAIN AND PITUITARY; EVIDENCE FOR TWO SPECIFIC PROCESSING PATTERNS, Pages 166-169, S. Zakarian, D.G. Smyth
MEASUREMENT OF MET-ENKEPHALIN(ARG6, PHE7) IN RAT BRAIN BY SPECIFIC RADIOIMMUNOASSAY DIRECTED AT METHIONINE SULPHOXIDE ENKEPHALIN (ARG6, PHE7), Pages 170-172, M.R. Boarder, A.J. Lockfeld, J.D. Barchas
OPIOID PEPTIDE IN THE DOG CANINE PULP?, Pages 173-175, T. Kudo, N. Yonehara, T. Hayashi, R. Inoki, T. Nishimoto, M. Akai
SUBCELLULAR LOCALIZATION OF ANALGESIC DIPEPTIDE, KYOTORPHIN (TYR-ARG) IN THE RAT BRAIN, Pages 176-178, H. Ueda, K. Tatsumi, H. Shiomi, H. Takagi
RELEASE OF ENDOGENOUS OPIOIDS FROM SPINAL CORD IN VIVO FOLLOWING SCIATIC NERVE STIMULATION, Pages 179-181, K. Jhamandas, T.L. Yaksh, L. Bergstrom, J.-Y. Wang, L. Terenius
NOXIOUS STIMULUS-INDUCED RELEASE OF MET-ENKEPHALIN FROM THE NUCLEUS RETICULARIS GIGANTOCELLULARIS OF THE RAT, Pages 182-184, Y. Kuraishi, M. Sugimoto, H. Takagi
INTESTINAL OPIOIDS MAY MODULATE THE ACTION OF ACETYLCHOLINE ON PERISTALSIS IN VITRO. RELEASE STUDIES POINT TO A POSSIBLE ROLE FOR DYNORPHIN IN THE CONTROL OF PERISTALSIS, Pages 185-187, W. Kromer, H. Schmidt, V. Höllt
INHIBITION OF THEIR BREAKDOWN AND RELEASE OF ENDOGENOUS OPIOID PEPTIDES FROM THE MYENTERIC PLEXUS-LONGITUDINAL MUSCLE OF THE GUINEA-PIG ILEUM, Pages 188-190, A.T. McKnight, A.D. Corbett
PROPERTIES OF ENKEPHALINASE FROM MOUSE AND HUMAN BRAIN, Pages 191-194, B. Malfroy, C. Llorens, Jean Charles Schwartz, E. Soroca, B. Roques, J. Roxy, J.L. Morgat, F. Javoy Agid, Y. Agid
DISCRETE REGIONAL DISTRIBUTION FOR ENKEPHALINASE AND AMINOPEPTIDASE IN MICRODISSECTED RAT BRAIN, Pages 195-197, Susan Sullivan, Jack D. Barchas, George Paxinos, Huda Akil
OPIATES CAUSE ACTIVATION OF A CALCIUM-DEPENDENT POTASSIUM CONDUCTANCE, Pages 200-201, K. Morita, R.A. North
ENKEPHALINERGIC PRESYNAPTIC INHIBITION IN MAMMALIAN SYMPATHETIC GANGLIA, Pages 202-204, S. Konishi
ACTIONS OF ENKEPHALIN ON SINGLE NEURONS IN CILIARY GANGLIA, Pages 205-207, Y. Katayama, S. Nishi
THE DISTRIBUTION OF RECEPTORS FOR ENKEPHALIN AND MORPHINE IN THE DORSAL HORN OF THE CAT, Pages 208-210, A.W. Duggan, S.M. Johnson, C.R. Morton
MUTUAL INHIBITION OF SPINAL NOCICEPTIVE PATHWAYS, Pages 211-213, B.R. Sastry
DIFFERENTIAL EFFECTS OF OPIOIDS ON SINGLE NEURONES IN RAT BRAIN, Pages 214-216, Anne Brookes, P.B. Bradley
POSSIBLE EXISTENCE OF ENKEPHALINERGIC NEURONS IN THE STRIATO-PALLIDAL PATHWAY IN THE RAT BRAIN, Pages 217-219, K. Iwatsubo, N. Oheda, R. Inoki
EXCITATORY ACTION OF MICROELECTROPHORETICALLY APPLIED KYOTORPHIN (TYR-ARG) ON UNITARY ACTIVITY IN THE RAT CEREBRAL CORTEX, Pages 220-222, M. Yamamoto, K. Kawamuki, M. Satoh, H. Takagi
ENDORPHINS AS MEDIATORS OF ETHANOL ACTIONS: MULTIDISCIPLINARY TESTS, Pages 223-225, F.E. Bloom, G.R. Siggins, Q. Pittman, E. French, T. Berger
THE MODULATORY EFFECT OF MORPHINE AND MONOAMINE OXIDASE B (MAO-B) SYSTEM ON ENKEPHALIN-INDUCED SEIZURES, Pages 226-228, O.E. Ukponmwan, M.R. Dzoljic
USE OF THE NOVEL OPIATE, β-FUNALTREXAMINE (β-FNA) IN THE ELUCIDATION OF RECEPTOR TYPES INVOLVED IN OPIATE-MEDIATED RESPIRATORY DEPRESSION, Pages 229-231, Susan J. Ward, A.E. Takemori, P.S. Portoghese
DIURNAL RHYTHM IN RESPONSE TO NOXIOUS STIMULI - INCREASE OF MET-ENKEPHALIN IN GLOBUS PALLIDUS, Pages 232-234, D.L. Wesche, R.C.A. Frederickson
EFFECTS OF PSYCHOTROPIC DRUGS ON THE LEVELS OF ENKEPHALINS, THEIR RECEPTORS AND ENKEPHALINASE IN RAT BRAIN, Pages 235-237, M. Takahashi, R. Izumi, H. Kaneto, M. Koida
CHANGES OF BRAIN IMMUNOREACTIVE DYNORPHIN CONTENT FOLLOWING AMYGDALOID-KINDLED AND RECCURENT SEIZURES, Pages 238-240, R. Przewłocki, W. Lasoń, R. Stach, D. Kacz, L. Stala, B. Przewłocka
EFFECTS OF FEEDING AND DRINKING ON IMMUNOREACTIVE BETA-ENDORPHIN AND ACTH LEVELS IN PLASMA AND HYPOTHALAMUS IN RATS, Pages 241-243, H. Takahashi, T. Motomatsu, T. Okajima, H. Oma, K. Kato, H. Ibayashi
PITUITARY ENDORPHIN LEVELS FOLLOWING THE ADMINISTRATION OF BENZAMIDE SUBSTITUTES, Pages 244-246, G. Giagnoni, A. Santagostino, G.M. Scoto, C. Spadaro, S. Spampinato, S. Ferri, S. Candeletti
OPIOID AND DOPAMINE RECEPTOR INTERACTIONS IN MAMMALIAN BRAIN, Pages 247-249, M. Makman, I. Hirschhorn, E. Gardner, L. Thal, S. Walczak, B. Dvorkin, D. Hittner, S. Horowitz
THE ROLE OF DOPAMINERGIC SYSTEM ON MORPHINE ANALGESIA IN MICE, Pages 250-252, K. Kamata, K. Ogawa, T. Kameyama
MORPHINE PRODUCES DIFFERENT EFFECTS ON SUBTYPES OF MESENCEPHALIC DOPAMINE SYSTEMS, Pages 253-256, N.L. Ostrowski, L.A. Chiodo, R. Keller, A.R. Caggiula
EFFECT OF ADRENERGIC DRUGS ON THE CENTRAL ANTIDIURETIC ACTION OF MORPHINE IN RATS, Pages 257-259, F. Huidobro, J. Pablo Huidobro-Toro
EFFECT OF MORPHINE ON ATP-STIMULATED 45Ca++ UPTAKE IN SUBCELLULAR FRACTIONS OF RAT BRAIN, Pages 260-262, Stella T. Chao, Federico Guerrero-Munoz, E. Leong Way
SPINAL MECHANISMS IN THE EFFECTS OF FENTANYL AND MORPHINE ON THE RAT TAIL FLICK, Pages 264-266, J. de Vry, R.H.W.M. van den Hoogen, F.C. Colpaert
STRONG ANALGESIC ACTIVITY OF LEU-ENKEPHALIN AFTER INHIBITION OF BRAIN AMINOPEPTIDASE: A PHARMACOLOGICAL STUDY, Pages 267-269, A. Carenzi, V. Frigeni, D. Della Bella
OPIOID AND NONOPIOID MECHANISMS OF STRESS-INDUCED ANALGESIA, Pages 270-272, S.F. Maier, R.C. Drugan, J.W. Grau, R.L. Hyson, A.J. MacLennan, J. Madden IV, J.D. Barchas
ANTINOCICEPTIVE AND TOXIC ACTIVITIES OF INTRACEREBROVENTRICULARLY (ICV) ADMINISTERED MORPHINE (M), 6-ACETYLMORPHINE (AM) AND 3,6-DIACETYLMORPHINE (DAM) IN MICE, Pages 273-275, JASON G. UMANS, CHARLES E. INTURRISI
POSSIBLE INVOLVEMENT OF INTRINSIC OPIOID PEPTIDES AND SEROTONIN IN PHENYLETHYLAMINE ANALOG-INDUCED ANALGESIA, Pages 276-278, K. Kubota, Y. Matsuoka, M. Sakuma, T. Hirano, T. Uruno, N. Sunagane
ANALGESIC PROPERTIES OF D-PHENYLALANINE, BACITRACIN AND PUROMYCIN IN MICE: RELATIONSHIP TO INHIBITION OF ENKEPHALINASE AND BETA ENDORPHINASE, Pages 279-281, S. Ehrenpreis, J. Greenberg, K. Kubota, S. Myles
CHANGES IN ANTINOCICEPTION AFTER EXPOSURE OF ANIMALS DURING EARLY DEVELOPMENT TO CHRONIC STRESS AND CHRONIC ADMINISTRATION OF NARCOTIC ANALGESICS, Pages 282-284, A.A. Larson
DYNORPHIN: DIFFERENTIAL INTERACTIONS WITH OPIATES AND PEPTIDES IN NAIVE AND MORPHINE TOLERANT MICE, Pages 285-287, F. Cankat Tulunay, M.F. Jen, N.M. Lee
CENTRAL NOREPINEPHRINE IN ACUPUNCTURE ANALGESIA: DIFFERENTIAL EFFECTS IN BRAIN AND SPINAL CORD, Pages 288-290, C.W. Xie, J. Tang, J.S. Han
AFFERENT AND EFFERENT PATHWAYS IN ACUPUNCTURE ANALGESIA AND THEIR CORRELATION WITH MORPHINE ANALGESIA, Pages 291-293, C. Takeshige, H. Mera, M. Kobori, T. Sato, C.P. Luo
SUPPRESSION BY MORPHINE AND ACUPUNCTURE ON NOXIOUS INFORMATION IN THE RAT CENTRAL NERVOUS SYSTEM, Pages 294-296, A. Iriki, K. Toda, H. Tanaka
PARALLEL INDIVIDUAL VARIATIONS IN EFFECTIVENESS OF ACUPUNCTURE, MORPHINE ANALGESIA AND DORSAL PAG-SPA AND THEIR ABOLITION BY D-PHENYLALANINE, Pages 297-299, C. Takeshige, M. Murai, M. Tanaka
THE ROLE OF CENTRAL 5-HYDROXYTRYPTAMINE IN ACUPUNCTURE ANALGESIA AND ACUPUNCTURE TOLERANCE, Pages 300-302, J. Tang, S.J. Li, C.W. Xie, J.S. Han
CENTRAL NOREPINEPHRINE: ITS IMPLICATION IN THE DEVELOPMENT OF ACUPUNCTURE TOLERANCE, Pages 303-305, J.S. Han, C.W. Xie, J. Tang
Aß NERVE IMPULSE PRODUCES ELECTROACUPUNCTURE ANALGESIA IN RAT, Pages 306-308, K. Toda
ACUPUNCTURE SUPPRESSES THE JAW OPENING REFLEX RELATED TO NOXIOUS INPUT IN RAT, Pages 309-311, A. Iriki, K. Toda
EFFECTS OF ELECTROACUPUNCTURE ON THE LEVELS OF ENDORPHINS AND SUBSTANCE P IN HUMAN LUMBAR CSF, Pages 312-314, S. Nakano, E. Ikezono
CSF ENDORPHIN LEVELS IN CHRONIC PAIN PATIENTS AND IN PATIENTS BEFORE AND AFTER A PLACEBO PAIN RELIEF, Pages 315-317, B.E. Miller, S. Karkera, W.L. Byrne, J.J. Lipman, K.S. Mays, W.C. North
β-ENDORPHIN IN OBSTETRIC ANALGESIA, Pages 318-320, T. Oyama, A. Matsuki, T. Taneichi, N. Ling, R. Guillemin
DESCENDING INHIBITION IN HUMAN SPINAL CORD, Pages 321-323, K. Shimoji, H. Shimizu, Y. Maruyama, M. Matsuki, H. Kuribayashi, H. Fujioka
NEUROLEPTIC-LIKE AND ANTI-PSYCHOTIC ACTION OF γ-TYPE ENDORPHINS, Pages 326-328, Jan M. van Ree
MULTI-DIMENSIONAL ANALYSES OF BEHAVIOR IN MICE TREATED WITH ENDORPHINS, Pages 329-331, M. Ukai, T. Kameyama
EFFECTS OF OPIOID DRUGS ON ACTIVE AVOIDANCE BEHAVIOR OF THE RAT, Pages 332-334, A. Zanotti, F. Drago, B. Bohus
BEHAVIORAL EFFECTS OF PROLACTIN: INVOLVEMENT OF OPIOID RECEPTORS, Pages 335-337, F. Drago, W.H. Gispen, B. Bohus
INTERACTION BETWEEN MORPHINE AND PHENCYCLIDINE: INTOXICATION AND CROSS-TOLERANCE, Pages 338-340, T. Nabeshima, S.P. Sivam, T. Kameyama, I.K. Ho
ENKEPHALINERGIC MODULATION OF CIRCLING BEHAVIOUR INDUCED BY DOPAMINE IN THE NUCLEUS ACCUMBENS AND NUCLEUS CAUDATUS, Pages 341-343, I.M. Jones, C.W.T. Pilcher
EXOGENOUS OPIOIDS AND DRINKING AND FEEDING, Pages 344-346, L.D. Reid, N.L. Ostrowski, S.M. Siviy, G.A. Rockwood
UNUSUAL BEHAVIORAL PROPERTIES OF SOME NEW OPIOID PEPTIDES, Pages 347-349, C.R. Strong, P.P. Auerbach, E.T. Wei, J.K. Chang
THE ROLE OF ENDORPHINS IN SCHIZOPHRENIA: CLINICAL STUDIES, Pages 350-352, P.A. Berger, J.D. Barchas, H. Akil, S.J. Watson
NALOXONE REVERSES INDUCED ISCHEMIC NEUROLOGIC DEFICIT IN GERBILS, Pages 353-355, Y. Hosobuchi, D.S. Baskin, S.K. Woo, H.H. Loh
NALTREXONE AND PSYCHOTHERAPY, Pages 356-358, N. Washton, R. Resnick, A. Washton
PATIENT CONTROL OF METHADONE MAINTENANCE DOSE, Pages 359-361, P. Butler, R. Resnick, A. Washton
LAAM INSTEAD OF TAKE-HOME METHADONE, Pages 362-363, R.B. Resnick, A.M. Washton, J. Garwood, J. Perzel Jr.
EFFECTS OF CHRONIC EXOGENOUS OPIOID ADMINISTRATION ON LEVELS OF ONE ENDOGENOUS OPIOID (β-ENDORPHIN) IN MAN, Pages 364-366, M.J. Kreek, S.L. Wardlaw, J. Friedman, B. Schneider, A.G. Frantz
NALOXONE AND THYROTROPIN RELEASING HORMONE HAVE ADDITIVE EFFECTS IN REVERSING ENDOTOXIC SHOCK, Pages 367-369, John W. Holaday, Alan I. Faden
THE ROLE OF ENKEPHALINS IN BLOOD PRESSURE IN THE BRAIN, Pages 370-372, T. Yukimura, G. Stock, H. Stumpf, Th. Unger, D. Ganten
ACTIVE SITES IN THE β-ENDORPHIN STRUCTURE FOR ACTIVATION OF THE EPSILON-OPIATE RECEPTOR, Pages 374-376, J. Pablo Huidobro-Toro, Epifania Caturay, Nancy M. Lee, Horace H. Loh, E. Leong Way
CRITICAL COMPONENTS OF OPIOID PEPTIDES FOR SPECIFIC RECOGNITION OF μ AND δ RECEPTORS, Pages 377-379, G. Gacel, M.C. Fournié-Zaluski, M. David, J.C. Meunier, J.L. Morgat, B.P. Roques
HIGHLY ACTIVE DIPEPTIDE AND TRIPEPTIDE ENKEPHALIN ANALOGS, Pages 380-382, R.J. Vavrek, E.J. York, L.-H. Hsi, J.M. Stewart
TWO NEW CLASSES OF CYCLIC ENKEPHALIN ANALOGS WITH HIGH POTENCY AND SPECIFICITY FOR μ-RECEPTORS, Pages 383-385, P.W. Schiller, J. DiMaio, B. Eggimann, C. Lemieux, T.M.-D. Nguyen
“MINIMAL SEGMENT” OF ENKEPHALIN FOR ANALGESIA: SYNDYPHALIN (SD)-33, A SIMPLE TRIPEPTIDE ALKYLAMIDE WITH PROLONGED SUBCUTANEOUS ANALGESIC ACTIVITY, Pages 386-388, T. Miyazaki, M. Yamaguchi, T. Akita, H. Moritoki, M. Takei, Y. Kiso, H. Nakamura
THE ANALGESIC EFFECTS OF CYCLIC DIPEPTIDES BY INTRACEREBRAL ADMINISTRATION IN CONSCIOUS MICE AND RATS, Pages 389-391, S. Sakurada, T. Sakurada, S. Kawamura, T. Satoh, R. Andoh, K. Kisara, Y. Sasaki, K. Suzuki
SYNTHETIC OPIOID α-CASEIN PEPTIDES. STRUCTURE ACTIVITY RELATIONSHIP, Pages 392-395, C. Zioudrou, S. Loukas, D. Varoucha, W.A. Klee, R.A. Streaty
SOME STRUCTURE-ACTIVITY RELATIONSHIPS IN THE 2′-MERCAPTOBENZOMORPHAN SERIES, Pages 396-398, E. Imai, M. Ban, M. Hori, M. Niwa, M. Nozaki, H. Fujimura
CHEMICAL STRUCTURE AND PHARMACOLOGICAL ACTIVITIES OF DIPHENYLETHYLPIPERAZINE DERIVATIVES, Pages 399-401, H. Nakamura, K. Natsuka, S. Motoyoshi, Y. Yokoyama, K. Ishii, M. Shimizu
PERIPHERAL SELECTIVITY OF QUATERNARY NARCOTIC ANTAGONISTS:RELATIVE ABILITY TO PREVENT GASTROINTESTINAL TRANSIT INHIBITION AND ANTINOCICEPTION IN MORPHINIZED RATS., Pages 402-404, L. Manara, G. Bianchi, R. Fiocchi, A. Tavani
STRUCTURE-ACTIVITY RELATIONSHIP STUDY OF AFFINITY LABELS THAT ARE SPECIFIC FOR μ OPIOID RECEPTORS, Pages 405-407, P.S. Portoghese, L.M. Sayre, D.L. Larson, D.S. Fries, A.E. Takemori
ARYLAZIDO-DERIVATIVES OF 14B-AMINOMORPHINONE : POTENTIAL PHOTOAFFINITY LIGANDS FOR OPIATE RECEPTORS, Pages 408-410, M.J. Rance, R.J. Kobylecki, A.C. Lane, M.J. Holdgate, E.A. Barnard
ANTAGONIST-AGONIST ACTIVITY OF SOME N-SUBSTITUTED BENZOMORPHANS, Pages 411-413, N. Kawamura, T. Kataoka, E. Imai, T. Iwamura, M. Hori, M. Niwa, M. Nozaki, H. Fujimura
THE ACTION OF 2-AMINOTETRALIN (2-AT) DERIVATIVES ON HUMAN PLASMA CHOLINESTERASE (HPC), Pages 414-416, A. Gero
HOW QUANTUM CHEMISTRY CAN DELINEATE THE DIFFERING MOLECULAR REQUISITES FOR INTERACTION WITH μ, δ, κ, σ AND OTHER OPIATE RECEPTORS, Pages 417-419, Joyce J. Kaufman
OPIATE AND CLONIDINE DEPENDENCE IN THE FINAL CHOLINERGIC MOTONEURONE OF THE GUINEA-PIG ISOLATED ILEUM, Pages 422-424, H.O.J. Collier
CROSS-TOLERANCE AND CROSS-DEPENDENCE ON MULTIPLE OPIATE RECEPTORS OF THE GUINEA-PIG ILEUM, Pages 425-427, R. Schulz, M. Wüster, E. Seidl
PROPERTIES OF OPIATE RECEPTOR BINDING IN AN OPIATE TOLERANT STATE, Pages 428-430, Kuniko Eguchi, Mizue Makimura, Yoshie Murakoshi
IMPORTANCE OF OPIATE RECEPTORS OF THE SUBSTANTIA GELATINOSA TO MORPHINE TOLERANCE AND DEPENDENCE OF CAT DORSAL HORN NEURONES, Pages 431-433, S.M. Johnson, A.W. Duggan
TOLERANCE TO ELECTROACUPUNCTURE AND ITS CROSS TOLERANCE TO MORPHINE, Pages 434-436, J.S. Han, S.J. Li, J. Tang
ACUPUNCTURE AND MORPHINE ANALGESIA INHIBITORY SYSTEMS AND ITS CORRELATION WITH MORPHINE TOLERANCE, Pages 437-439, C. Takeshige, M. Kobori, H. Mera
PHOSPHORYLATION OF STRIATAL SYNAPTIC PLASMA MEMBRANE PROTEINS FROM MORPHINE-TOLERANT RATS, Pages 440-442, Doris H. Clouet, Norman Williams
PHYSICAL DEPENDENCE LIABILITY OF TETRAPEPTIDE ACYLHYDRAZIDE ANALOGS OF ENKEPHALIN IN RATS, Pages 443-445, K. Kawai, S. Kuzuna, H. Ishii, M. Fujino
NALOXONE REVERSIBLE EFFECT OF MORPHINE ON SUBSTANCE P NEURONS IN THE RAT SPINAL CORD, Pages 446-448, N. Eric Naftchi
INVOLVEMENT OF GABA IN THE ACUTE AND CHRONIC EFFECTS OF MORPHINE:NOCICEPTIVE GABA RELEASE AND RECEPTOR BINDING STUDIES, Pages 449-451, S.P. Sivam, T. Nabeshima, I.K. Ho
THE INVOLVEMENT OF BRAIN HISTAMINERGIC MECHANISMS IN THE WITHDRAWAL PHASE OF MORPHINE DEPENDENCE, Pages 452-454, M.R. Fennessy, S.J. Lewis
A POTENTIATION OF PHYSICAL DEPENDENCE BY 6-CONJUGATION OF MORPHINE AND NALORPHINE, Pages 455-457, K. Oguri, I. Mori, T. Hirano, J. Shigezane, E. Sonoda, H. Yoshimura
TRANSPORT AND BINDING IN VIVO OF 3H-NALOXONE IN BRAINS OF MORPHINE DEPENDENT AND WITHDRAWN MICE, Pages 458-460, R. Oishi, A.E. Takemori
INHIBITION OF TOLERANCE TO HUMAN BETA ENDORPHIN BY A LINEAR AND A CYCLIC PEPTIDE, Pages 461-463, Hemendra N. Bhargava
DIFFERENTIAL EFFECTS OF THYROLIBERIN ON TOLERANCE TO THE ANALGESIC AND HYPOTHERMIC EFFECTS OF MORPHINE IN MICE, Pages 464-466, Hemendra N. Bhargava
INDUCTION OF PHYSICAL DEPENDENCE IN RATS BY SHORT TREATMENT OF MORPHINE-ADMIXED FOOD, Pages 467-468, T. Suzuki, M. Shimada, T. Yoshii, S. Yanaura
TOLERANCE AS THE ONLY SIGN OF WITHDRAWAL IN OPIATE DEPENDENT CHICK FETUSES, Pages 469-471, S.B. Sparber, M.D. Kuwahara
CAFFEINE ENHANCES MORPHINE DEPENDENCE IN HUMANS, Pages 472-474, Reese T. Jones
SCHEDULE INDUCED SELF INJECTION OF HEROIN: DOSE RESPONSE RELATIONSHIPS, Pages 475-477, Jan M. van Ree, Meredith Wallace
OPIATE DETOXIFICATION USING LOFEXIDINE, Pages 478-480, A. Washton, R. Resnick, J. Garwood
DETECTION OF MORPHINONE AS A NEW METABOLITE OF MORPHINE IN GUINEA PIG URINE, Pages 481-483, Takashi Ishida, Shigeru Yamano, Satoshi Toki
KETAMINE-LIKE DISCRIMINATIVE CHARACTERISTICS OF THE STEREOISOMERS OF METAZOCINE, CYCLAZOCINE, AND SKF 10,047 IN RHESUS MONKEYS, Pages 484-486, R.E. Solomon, S. Herling, J.H. Woods
CONCLUDING REMARKS, Pages 487-490, H.O.J. Collier
Author Index, Pages 491-493