Tumors of the Central Nervous System, Volume 1: Gliomas: Glioblastoma (Part 1)

Front Matter....Pages i-xxi
Front Matter....Pages 1-1
Introduction....Pages 3-8
Molecular Classification of Gliomas....Pages 9-19
Front Matter....Pages 21-21
Glioblastoma: Endosialin Marker for Pericytes....Pages 23-29
Glioma Grading Using Cerebral Blood Volume Heterogeneity....Pages 31-43
The Role of Ectonucleotidases in Glioma Cell Proliferation....Pages 45-51
Gliomas: Role of Monoamine Oxidase B in Diagnosis....Pages 53-59
Glioma: Role of Integrin in Pathogenesis and Therapy....Pages 61-66
Proton Magnetic Resonance Spectroscopy in Intracranial Gliomas....Pages 67-79
Infiltration Zone in Glioma: Proton Magnetic Resonance Spectroscopic Imaging....Pages 81-88
Malignant Gliomas: Role of E2F1 Transcription Factor....Pages 89-97
The Role of Glucose Transporter-1 (GLUT-1) in Malignant Gliomas....Pages 99-108
Malignant Gliomas: Role of Platelet-Derived Growth Factor Receptor A (PDGFRA)....Pages 109-118
Molecular Methods for Detection of Tumor Markers in Glioblastomas....Pages 119-130
Role of MGMT in Glioblastomas....Pages 131-136
Glioblastomas: Role of CXCL12 Chemokine....Pages 137-146
Cell Death Signaling in Glioblastoma Multiforme: Role of the Bcl2L12 Oncoprotein....Pages 147-157
Glioblastoma Multiforme: Role of Polycomb Group Proteins....Pages 159-166
Glioblastoma Multiforme: Role of Cell Cycle-Related Kinase Protein (Method)....Pages 167-171
Front Matter....Pages 173-173
Markers of Stem Cells in Gliomas....Pages 175-190
Efficient Derivation and Propagation of Glioblastoma Stem-Like Cells Under Serum-Free Conditions Using the Cambridge Protocol....Pages 191-204
Front Matter....Pages 173-173
Glioma Cell Lines: Role of Cancer Stem Cells....Pages 205-212
Glioblastoma Cancer Stem Cells: Response to Epidermal Growth Factor Receptor Kinase Inhibitors....Pages 213-226
Front Matter....Pages 227-227
Low- and High-Grade Gliomas: Extensive Surgical Resection....Pages 229-237
Brainstem Gangliogliomas: Total Resection and Close Follow-Up....Pages 239-242
Glioblastoma: Temozolomide-Based Chemotherapy....Pages 243-248
Drug-Resistant Glioma: Treatment with Imatinib Mesylate and Chlorimipramine....Pages 249-258
Glioblastoma Multiforme: Molecular Basis of Resistance to Erlotinib....Pages 259-267
Enhanced Glioma Chemosensitivity....Pages 269-276
Malignant Glioma Patients: Anti-Vascular Endothelial Growth Factor Monoclonal Antibody, Bevacizumab....Pages 277-290
Aggravating Endoplasmic Reticulum Stress by Combined Application of Bortezomib and Celecoxib as a Novel Therapeutic Strategy for Glioblastoma....Pages 291-298
Targeted Therapy for Malignant Gliomas....Pages 299-307
Glioblastomas: HER1/EGFR-Targeted Therapeutics....Pages 309-320
Epidermal Growth Factor Receptor Inhibition as a Therapeutic Strategy for Glioblastoma Multiforme....Pages 321-336
Role of Acyl-CoA Synthetases in Glioma Cell Survival and Its Therapeutic Implication....Pages 337-340
Malignant Glioma Patients: Combined Treatment with Radiation and Fotemustine....Pages 341-347
Malignant Glioma Immunotherapy: A Peptide Vaccine from Bench to Bedside....Pages 349-356
Malignant Glioma: Chemovirotherapy....Pages 357-364
Intracranial Glioma: Delivery of an Oncolytic Adenovirus....Pages 365-370
Use of Magnetic Resonance Spectroscopy Imaging (MRSI) in the Treatment Planning of Gliomas....Pages 371-378
Malignant Glioma Cells: Role of Trail-Induced Apoptosis....Pages 379-387
Front Matter....Pages 389-389
Long-Term Survivors of Glioblastoma....Pages 391-398
Glioblastoma Patients: p15 Methylation as a Prognostic Factor....Pages 399-404
Back Matter....Pages 405-434