TRP Channels as Therapeutic Targets: From Basic Science to Clinical Use

Content: 
Front Matter, Pages i-ii
Copyright, Page iv
Contributors, Pages ix-xi, M. Allen McAlexander, Ganesan Baranidharan, Ralf Baron, Arun K. Bhaskar, Mahendra Bishnoi, Jill-Desiree Brederson, Dorothy Cimino Brown, Nigel W. Bunnett, Ingolf Cascorbi, Michael J. Caterina, Ana Charrua, Francisco Cruz, Matthew A.J. Duncton, Madeleine Ennis, Susan Fleetwood-Walker, Ehud Goldin, Arthur Gomtsyan, Huizhen Huang, Gerald Hunsberger, Michael J. Iadarola, Neelima Khairatkar Joshi,  et al.
Preface, Page xiii
Chapter 1 - An Introduction to Transient Receptor Potential Ion Channels and Their Roles in Disease, Pages 1-12, Michael J. Caterina
Chapter 2 - Transient Receptor Potential Dysfunctions in Hereditary Diseases: TRP Channelopathies and Beyond, Pages 13-33, Balázs István Tóth, Bernd Nilius
Chapter 3 - The Role of TRPV1 in Acquired Diseases: Therapeutic Potential of TRPV1 Modulators, Pages 35-58, Mahendra Bishnoi, Pragyanshu Khare, Kanthi K. Kondepudi, Louis S. Premkumar
Chapter 4 - TRP Gene Polymorphism and Disease Risk, Pages 59-87, Ina Kraus-Stojanowic, Ralf Baron, Ingolf Cascorbi
Chapter 5 - Use of Topical Capsaicin for Pain Relief, Pages 89-98, Ganesan Baranidharan, Arun K. Bhaskar
Chapter 6 - TRPV1 Agonist Cytotoxicity for Chronic Pain Relief: From Mechanistic Understanding to Clinical Application, Pages 99-118, Dorothy Cimino Brown, Michael J. Iadarola
Chapter 7 - Intravesical Capsaicin and Resiniferatoxin for Bladder Disorders, Pages 119-127, Ana Charrua, Francisco Cruz
Chapter 8 - Clinical and Preclinical Experience with TRPV1 Antagonists as Potential Analgesic Agents, Pages 129-144, Arthur Gomtsyan, Jill-Desiree Brederson
Chapter 9 - Transient Receptor Potential Ankyrin 1 Channel Antagonists for Pain Relief, Pages 145-162, Ari Koivisto, Antti Pertovaara
Chapter 10 - TRPA1 Antagonists as Potential Therapeutics for Respiratory Diseases, Pages 163-193, Jessica Tan, Gerald Hunsberger, Christopher Neipp, M. Allen McAlexander
Chapter 11 - Is TRPV3 a Drug Target?—A Decade of Learning, Pages 195-204, Neelima Khairatkar Joshi
Chapter 12 - Small Molecule Agonists and Antagonists of TRPV4, Pages 205-219, Matthew A.J. Duncton
Chapter 13 - Potential Therapeutic Applications for TRPV4 Antagonists in Lung Disease, Pages 221-238, Mary I. Townsley, James C. Parker
Chapter 14 - TRPM8 as a Target for Analgesia, Pages 239-262, Rory Mitchell, Susan Fleetwood-Walker
Chapter 15 - Connecting TRP Channels and Cerebrovascular Diseases, Pages 263-277, Anil Zechariah, Donald G. Welsh
Chapter 16 - Activating, Inhibiting, and Highjacking TRP Channels for Relief from Itch, Pages 279-291, Lindsey M. Snyder, Huizhen Huang, Sarah E. Ross
Chapter 17 - Role of TRP Channels in Skin Diseases, Pages 293-323, Mathias Sulk, Martin Steinhoff
Chapter 18 - Transient Receptor Potential Channels in Hypertension and Metabolic Syndrome, Pages 325-342, Zhiming Zhu, Daoyan Liu, Shiqiang Xiong
Chapter 19 - Transient Receptor Potential (TRP) Cation Channels in Diabetes, Pages 343-363, Koenraad Philippaert, Rudi Vennekens
Chapter 20 - TRP Channels in Cardiovascular Disease, Pages 365-383, Kavisha Singh, Nancy Luo, Paul Rosenberg
Chapter 21 - Targeting of Transient Receptor Potential Channels in Digestive Disease, Pages 385-403, Daniel P. Poole, TinaMarie Lieu, Nicholas A. Veldhuis, Pradeep Rajasekhar, Nigel W. Bunnett
Chapter 22 - TRP Channels in Cancer, Pages 405-418, Artem Kondratskyi, Natalia Prevarskaya
Chapter 23 - Are Brain TRPs Viable Targets for Curing Neurodegenerative Disorders and Improving Mental Health?, Pages 419-456, Bernd Nilius, Arpad Szallasi
Chapter 24 - Mucolipidosis Type IV: Part I, Pages 457-468, Ehud Goldin
Chapter 25 - TRPML1-Dependent Processes as Therapeutic Targets, Pages 469-482, Kartik Venkatachalam, Kirill Kiselyov
Chapter 26 - TRPs in Respiratory Disorders: Opportunities Beyond TRPA1, Pages 483-500, Alexander Zholos, Lorcan McGarvey, Madeleine Ennis
Chapter 27 - Conclusions, Pages 501-504, Magdalene Moran
Index, Pages 505-515