Transmethylations and the Central Nervous System

Front Matter....Pages I-VI
Introduction....Pages 1-3
Biochemistry of the Central Nervous System and Behavior....Pages 4-16
Transmethylating Enzymes....Pages 17-30
On the Development and Utilization of Assays for Biological Transmethylation Involving S-Adenosylmethionine....Pages 31-48
S-Adenosyl-L-Methionine (SAMe) and Biogenic Amine Methylation Processes....Pages 49-54
SAMe and Histamine....Pages 55-69
S-Adenosyl-L-Methionine and GABA Metabolism in the Brain....Pages 70-78
Effect of Acute Hyperammonemia on Metabolism and Cerebral Energy State....Pages 79-99
A Study of the Distribution of Radioactive S-Adenosylmethionine in the Experimental Animal....Pages 100-110
Concentrations of S-Adenosyl-L-Methionine in the CNS of Rats After Intramuscular and Intravenous Administration....Pages 111-113
The Subcellular Distribution of S-Adenosyl-L-Methionine (SAMe) in the Rat Brain....Pages 114-118
On Lowering S-Adenosylmethionine....Pages 119-120
Effects of S-Adenosyl-L-Methionine on the Behavior of Mice....Pages 121-131
Effects of Exogenous L-Dopa on the Metabolism of Methionine and S-Adenosylmethionine in the Brain....Pages 132-143
Human Blood Kinetics of S-Adenosyl-L-Methionine (SAMe)....Pages 144-146
S-Adenosyl-L-Methionine (SAMe) Blood Levels in Schizophrenia and Depression....Pages 147-150
A Polygraph Evaluation of the Effects of S-Adenosyl-L-Methionine (SAMe) on All-Night Sleep....Pages 151-169
Results and Possible Developments of the Clinical Use of S-Adenosyl-L-Methionine (SAMe) in Psychiatry....Pages 170-182
Back Matter....Pages 183-188