Toxicological profiles - Methyl mercaptan

TOXICOLOGICAL PROFILE FOR METHYL MERCAPTAN......Page 1
DISCLAIMER......Page 2
FOREWORD......Page 3
CONTENTS......Page 5
LIST OF FIGURES......Page 9
LIST OF TABLES......Page 11
1.1 WHAT IS METHYL MERCAPTAN?......Page 13
1.3 HOW CAN METHYL MERCAPTAN ENTER AND LEAVE MY BODY?......Page 14
1.6 WHAT RECOMMENDATIONS HAS THE FEDERAL GOVERNMENT MADE TO PROTECT HUMAN HEALTH?......Page 15
1.7 WHERE CAN I GET MORE INFORMATION?......Page 16
2.2 DISCUSSION OF HEALTH EFFECTS BY ROUTE OF EXPOSURE......Page 17
2.2.1.2 Systemic Effects......Page 18
2.2.1.3 Immunological Effects......Page 22
2.2.2.8 Cancer......Page 23
2.2.4.3 Immunological Effects......Page 24
2.3.1.1 Inhalation Exposure......Page 25
2.3.3 Metabolism......Page 26
2.4 RELEVANCE TO PUBLIC HEALTH......Page 27
2.5 BIOMAREERS OF EXPOSURE AND EFFECT......Page 29
2.5.1 Biomarkers Used to Identify and/or Quantify Exposure to Methyl Mercaptan......Page 30
2.7 POPULATIONS THAT ARE UNUSUALLY SUSCEPTIBLE......Page 31
2.8 MITIGATION OF EFFECTS......Page 32
2.9 ADEQUACY OF THE DATABASE......Page 33
2.9.2 Data Needs......Page 34
2.9.3 On-going Studies......Page 38
3.2 PHYSICAL AND CHEMICAL PROPERTIES......Page 39
4.4 DISPOSAL......Page 43
5.2.1 Air......Page 45
5.3.1 Transport and Partitioning......Page 47
5.3.2.1 Air......Page 49
5.4.4 Other Environmental Media......Page 50
5.7 ADEQUACY OF THE DATABASE......Page 51
5.7.1 Data Needs......Page 52
5.7.2 On-going Studies......Page 54
6.1 BIOLOGICAL MATERIALS......Page 55
6.3 ADEQUACY OF THE DATABASE......Page 57
6.3.1 Data Needs......Page 59
6.3.2 On-going Studies......Page 60
7. REGULATIONS AND ADVISORIES......Page 61
8. REFERENCES......Page 63
EPA Health Advisory......Page 75
Mutagen......Page 76
Short-Term Exposure Limit......Page 77
Uncertainty Factor (UF)......Page 78
USER'S GUIDE......Page 79
ACRONYMS, ABBREVIATIONS, AND SYMBOLS......Page 88
PEER REVIEW......Page 92