Toxicological profiles - Bromomethane

TOXICOLOGICAL PROFILE FOR BROMOMEHTHANE......Page 1
CONTENTS......Page 5
DISCLAIMER......Page 2
FOREWORD......Page 3
LIST OF FIGURES......Page 8
LIST OF TABLES......Page 9
1.2 HOW MIGHT I BE EXPOSED TO BROMOMETHANE?......Page 10
1.4 HOW CAN BROMOMETHANE AFFECT MY HEALTH?......Page 11
1.7 WHERE CAN I GET MORE INFORMATION?......Page 12
2.2 DISCUSSION OF HEALTH EFFECTS BY ROUTE OF EXPOSURE......Page 13
2.2.1.1 Death......Page 14
2.2.1.2 Systemic Effects......Page 29
2.2.1.4 Neurological Effects......Page 31
2.2.1.8 Cancer......Page 32
2.2.2.2 Systemic Effects......Page 33
2.2.3 Dermal Exposure......Page 37
2.2.3.2 Systemic Effects......Page 38
2.3.1.3 Dermal Exposure......Page 40
2.3.3 Metabolism......Page 41
2.4 RELEVANCE TO PUBLIC HEALTH......Page 42
2.5.1 Biomarkers Used to Identify and/or Quantify Exposure to Bromomethane......Page 50
2.6 INTERACTIONS WITH OTHER CHEMICALS......Page 51
2.8 MITIGATION OF EFFECTS......Page 52
2.9.1 Existing Information on Health Effects of Bromomethane......Page 53
2.9.2 Data Needs......Page 55
3.2 PHYSICAL AND CHEMICAL PROPERTIES......Page 59
4.4 DISPOSAL......Page 64
5.2.1 Air......Page 67
5.2.3 Soil......Page 72
5.3.2.2 Water......Page 73
5.4.2 Water......Page 74
5.5 GENERAL POPULATION AND OCCUPATIONAL EXPOSURE......Page 77
5.7.1 Data Needs......Page 78
6. ANALYTICAL METHODS......Page 80
6.2 ENVIRONMENTAL SAMPLES......Page 81
6.3.1 Data Needs......Page 86
7. REGULATIONS AND ADVISORIES......Page 87
8. REFERENCES......Page 92
In Vivo......Page 109
Reference Dose......Page 110
Uncertainty Factor......Page 111
User s Guide......Page 112
Acronyms, Abbreviations, and Symbols......Page 117
PEER REVIEW......Page 121