Toxicological profiles - 2,4,6-trichlorophenol

TOXICOLOGICAL PROFILE FOR 2,4,6-TRICHLOROPHENOL......Page 1
CONTENTS......Page 5
DISCLAIMER......Page 2
FOREWORD......Page 3
LIST OF FIGURES......Page 8
LIST OF TABLES......Page 9
1.1 WHAT IS 2,4,6-TRICHLOROPHENOL?......Page 10
1.3 HOW CAN 2,4,6-TRICHLOROPHENOL ENTER AND LEAVE MY BODY?......Page 11
1.5 WHAT LEVELS OF EXPOSURE HAVE RESULTED IN HARMFUL HEALTH EFFECTS?......Page 12
1.8 WHERE CAN I GET MORE INFORMATION?......Page 22
2.2 DISCUSSION OF HEALTH EFFECTS BY ROUTE OF EXPOSURE......Page 23
2.2.2 Oral Exposure......Page 24
2.2.2.2 Systemic Effects......Page 25
2.2.2.5 Developmental Effects......Page 37
2.2.2.8 Cancer......Page 38
2.2.3.8 Cancer......Page 39
2.3.1.4 Other Routes of Exposure......Page 40
2.3.2.4 Other Routes of Exposure......Page 41
2.3.4.2 Oral Exposure......Page 42
2.4 RELEVANCE TO PUBLIC HEALTH......Page 43
2.5.1 Biomarkers Used to Identify or Quantify Exposure to 2,4,6-Trichloro-phenol......Page 51
2.7 POPULATIONS THAT ARE UNUSUALLY SUSCEPTIBLE......Page 52
2.8.1 Existing Information on Health Effects of 2,4,6-Trichlorophenol......Page 53
2.8.2 Identification of Data Needs......Page 55
3.1 CHEMICAL IDENTITY......Page 58
3.2 PHYSICAL AND CHEMICAL PROPERTIES......Page 59
4.1 PRODUCTION......Page 64
4.4 DISPOSAL......Page 65
5.2.1 Air......Page 66
5.2.3 Soil......Page 67
5.3.1 Transport and Partitioning......Page 68
5.3.2.2 Water......Page 71
5.4.1 Air......Page 72
5.4.4 Other Media......Page 73
5.5 GENERAL POPULATION AND OCCUPATIONAL EXPOSURE......Page 74
5.7.1 Identification of Data Needs......Page 75
6.1 BIOLOGICAL MATERIALS......Page 77
6.2 ENVIRONMENTAL SAMPLES......Page 91
6.3.1 Identification of Data Needs......Page 93
7. REGULATIONS AND ADVISORIES......Page 94
8. REFERENCES......Page 99
Developmental Toxicity......Page 121
Minimal Risk Level......Page 122
Teratogen......Page 123
User s Guide......Page 124
Acronyms, Abbreviations, and Symbols......Page 129
Peer Review......Page 133