Thyrotropin: Ultrasensitive THS measurement in clinical research and diagnostics

Preface\nContents\nI. Regulation of TSH-secretion\nBiosynthesis of Thyrotropin releasing hormone\nHormonal regulation of Thyrotropin gene expression\nRegulation of Thyrotropin secretion and its derangements\nTSH-Release and TSH-synthesis: two different effects of TRH\nFeedback regulation and thyroid status evaluated by an ultrasensitive TSH-IRMA in euthyroidism and borderline hyperthyroidism\nThe effect of Metoclopramide on the TSH and PRL response to TRH in patients treated for depression\nSecondary hyperthyroidism associated with pituitary chromophobe adenoma: Study of TSH chemistry and release\nHyperthyroidism and thyroid hormone resistance\nComparison of TSH secretory response and plasma TRH levels after intravenous and nasal TRH administration\nThyrotropin serum concentration as a function of peripheral concentrations of thyroxine, triiodothyronine, reverse triiodothyronine, and thyroliberin\nII. Sensitive methods for the measurements of TSH\nSensitive immunoassays for the determination of thyrotropin levels in serum\nStudies on different hypersensitive TSH tests\nClinical comparison of 5 kits for sensitive TSH determination in hyperthyroidism and in non thyroidal illness\nComparison by receiver operating characteristics (ROC) analysis of three thyrotropin assays in the diagnosis of hyperthyroidism\nComparative evaluation of high sensitivity TSH kits\nTrends in performance of clinical TSH assays as assessed by the United Kingdom EQAS for thyroid related hormones\nIII. TSH in non-thyroidal illness\nThyroidal and extrathyroidal influences on TSH before and after TRH stimulation\nParameters of thyroid function in patients on hemodialysis\nTSH-Immunoradiometric assay (IRMA) in geriatric patients\nLow T3 syndrome and pituitary thyrotrophin function in diabetes mellitus in relation to type of diabetes and metabolic control — a review\nTRH test and diagnostic of undefined secondary amenorrhea\nValue of an immunoradiometric assay for thyrotropin in non-thyroidal illness\nIV. TSH in clinical diagnostics\nThyrotropin — clinical relevance of sensitive TSH-assays\nTSH response to TRH as a function of basal serum TSH — new aspects in pituitary-thyroid regulation\nClinical value of blunted TSH-response\nSensitive TSH test in clinical routine: possibility of prediction of response to TRH from baseline TSH concentrations\nTSH measured with sensitive RIA method in euthyroid goiter patients\nApplication of a sensitive immunoradiometric assay (IRMA) for TSH in the diagnosis and follow-up thyroid disorders\nSignificance of TRH test in strumectomized patients for life-long thyroid hormone treatment\nDiagnostic significance of basal TSH-concentrations (TSH-IRMA)\nImpaired conversion of thyroxine to triiodothyronine causing elevated concentrations of thyroxine and TSH in an euthyroid patient\nTSH-levels after operation of autonomously functioning thyroid tissue-enucleation versus resection of solitary nodules\nSerum TSH determination by IRMA-mat-TSH assay in patients with functioning thyroid nodules\nHigh sensitivity TSH in assessing thyroid function of patients\nV. The thyroid TSH receptor and TSH receptor antibodies\nV The thyroid TSH receptor and TSH receptor antibodies\nTSH-receptor antibodies\nTSH-binding analysis and TSH-receptor distribution pattern in thyroid disease\nClinical significance of antibodies to the TSH-receptor (stimulating and blocking thyroid function)\nAutoantibodies reacting with thyroid plasma membranes in Graves\' disease: importance of multiple plasma membrane antigens\nThyroid growth stimulating immunoglobulins: Clinical significance in euthyroid goitre and relationship to thyrotropin-binding inhibiting antibodies\nDetection of antibodies directed against bovine TSH in patients with and without endocrine ophthalmopathy\nList of contributors\nAuthors\' index\nSubject index