Thomas' Hematopoietic Cell Transplantation, Third Edition

Contributors......Page 9
Preface to the First Edition......Page 16
Preface to the Second Edition......Page 17
Preface to the Third Edition......Page 18
Tribute......Page 19
List of Abbreviations......Page 21
Section 1 Scientific Basis for Hematopoietic Cell Transplantation......Page 27
E. Donnall Thomas A History of Bone Marrow Transplantation 1......Page 29
M. Horowitz Uses and Growth of Hematopoietic Cell Transplantation 2......Page 35
Paul J. Martin Overview of Hematopoietic Cell Transplantation Immunology 3......Page 42
Eric Mickelson & Effie W. Petersdorf Histocompatibility 4......Page 57
Lakshmi K. Gaur* Functional Evolution of the Major Histocompatibility Complex 5......Page 69
Claudio Brunstein & Catherine M. Verfaillie The Hematopoietic Microenvironment 6......Page 79
Peter M. Lansdorp Molecular Aspects of Stem Cell Renewal 7......Page 88
Markus G. Manz, Koichi Akashi & Irving L. Weissman Biology of Hematopoietic Stem and Progenitor Cells 8......Page 95
Colleen Delaney, Robert Andrews & Irwin Bernstein Expansion of Hematopoietic Stem Cells 9......Page 122
Thomas Moritz & David A. Williams Methods for Gene Transfer: Genetic Manipulation of Hematopoietic Stem Cells 10......Page 133
Donald B. Kohn & Gay M. Crooks Clinical Trials of Gene Marking and Gene Therapy Using Hematopoietic Stem Cells 11......Page 144
James H. Doroshow & Timothy Synold Pharmacologic Basis for High-Dose Chemotherapy 12......Page 156
William I. Bensinger & Ricardo Spielberger Preparative Regimens and Modification of Regimen-Related Toxicities 13......Page 184
Brenda Shank & Richard T. Hoppe Radiotherapeutic Principles of Hematopoietic Cell Transplantation 14......Page 204
Dana C. Matthews & Frederick R. Appelbaum Radioimmunotherapy and Hematopoietic Cell Transplantation 15......Page 224
Nelson J. Chao Pharmacology and the Use of Immunosuppressive Agents after Hematopoietic Cell Transplantation 16......Page 235
Robert J. Soiffer T-Cell Depletion to Prevent Graft-vs.-Host Disease 17......Page 247
Eileen Bryant & Paul J. Martin Documentation of Engraftment and Characterization of Chimerism Following Hematopoietic Cell Transplantation 18......Page 260
John G. Gribben Antibody Mediated Purging 19......Page 270
O. Michael Colvin Pharmacologic Purging of Bone Marrow 20......Page 280
Joanna B. Opalinska & Alan M. Gewirtz Molecular Inhibition of Gene Expression in Hematopoietic Cells 21......Page 284
Jerald P. Radich & Marilyn L. Slovak The Detection and Significance of Minimal Residual Disease 22 Total number of leukaemia cells......Page 298
George E. Sale, Howard M. Shulman & Robert C. Hackman Pathology of Hematopoietic Cell Transplantation 23......Page 312
Megan Sykes Mechanisms of Tolerance 24......Page 326
Judith A. Shizuru The Experimental Basis for Hematopoietic Cell Transplantation for Autoimmune Diseases 25......Page 350
Robert Korngold & Thea M. Friedman Murine Models for Graft-vs.-Host Disease 26......Page 370
James L.M. Ferrara & Joseph Antin The Pathophysiology of Graft-vs.-Host Disease 27......Page 379
Alexander Fefer Graft-vs.-Tumor Responses 28......Page 395
Stanley R. Riddell & Philip D. Greenberg Adoptive Immunotherapy with Antigen-Specific T Cells 29......Page 406
Allan D. Hess & Richard J. Jones Autologous Graft-vs.-Host Disease 30......Page 431
Joyce C. Niland Biostatistical Methods in Hematopoietic Cell Transplantation 31......Page 440
Stephanie J. Lee Outcomes Research in Hematopoietic Cell Transplantation 32......Page 460
Section 2 Patient-Related Issues in Hematopoietic Cell Transplantation......Page 473
Karl G. Blume & Michael D. Amylon The Evaluation and Counseling of Candidates for Hematopoietic Cell Transplantation 33......Page 475
Laura L. Adams & Angela A. Johns Clinical and Administrative Support for Hematopoietic Cell Transplant Programs 34......Page 489
Rosemary C. Ford, Judy Campbell & Juanita Madison Nursing Issues in Hematopoietic Cell Transplantation 35......Page 495
Susan K. Stewart The Patient’s Perspective 36......Page 509
David S. Snyder Ethical Issues in Hematopoietic Cell Transplantation 37......Page 514
Michael A. Andrykowski & Richard P. McQuellon Psychosocial Issues in Hematopoietic Cell Transplantation 38......Page 523
Karen Syrjala Assessment of Quality of Life in Hematopoietic Cell Transplantation Recipients 39......Page 533
D. Kathryn Tierney Sexuality after Hematopoietic Cell Transplantation 40......Page 545
Section 3 Sources of Hematopoietic Cells for Human Transplant......Page 555
Phyllis I. Warkentin, Lewis Nick & Elizabeth J. Shpall Hematopoietic Cell Procurement, Processing and Transplantation: Regulation and Accreditation 41......Page 557
Dennis L. Confer Hematopoietic Cell Donors 42......Page 564
Hal E. Broxmeyer & Franklin O. Smith Cord Blood Hematopoietic Cell Transplantation 43......Page 576
Alan W. Flake & Esmail D. Zanjani In Utero Transplantation 44......Page 591
Judith Ng-Cashin & Thomas Shea Mobilization of Autologous Peripheral Blood Hematopoietic Cells for Support of High-Dose Cancer Therapy 45......Page 602
Norbert Schmitz Peripheral Blood Hematopoietic Cells for Allogeneic Transplantation 46......Page 614
Scott D. Rowley Cryopreservation of Hematopoietic Cells 47......Page 625
Jürgen Finke & Roland Mertelsmann Recombinant Growth Factors after Hematopoietic Cell Transplantation 48......Page 639
Jeffrey W. Chell Hematopoietic Cell Donor Registries 49......Page 650
Section 4 Complications and Their Management......Page 659
Keith M. Sullivan Graft-vs.-Host Disease 50......Page 661
John R. Wingard & Helen L. Leather Bacterial Infections 51......Page 691
Janice (Wes) M.Y. Brown Fungal Infections after Hematopoietic Cell Transplantation 52......Page 709
John A. Zaia Cytomegalovirus Infection 53......Page 727
James I. Ito Herpes Simplex Virus Infections 54......Page 753
Ann M. Arvin Varicella-Zoster Virus Infections 55......Page 758
Richard F. Ambinder Epstein–Barr Virus Infection 56......Page 775
Michael Boeckh Other Viral Infections after Hematopoietic Cell Transplantation 57......Page 783
Simone I. Strasser & George B. McDonald Gastrointestinal and Hepatic Complications 58......Page 795
Harry Openshaw Neurological Complications of Hematopoietic Cell Transplantation 59......Page 837
Margaret R. O’Donnell Blood Group Incompatibilities and Hemolytic Complications of Hematopoietic Cell Transplantation 60......Page 850
Jeffrey McCullough Principles of Transfusion Support before and after Hematopoietic Cell Transplantation 61......Page 859
Robertson Parkman & Kenneth I. Weinberg Immune Reconstitution following Hematopoietic Cell Transplantation 62......Page 879
Clare A. Dykewicz Vaccination of Hematopoietic Cell Transplant Recipients 63......Page 888
David A. Horak Pulmonary Complications after Hematopoietic Cell Transplantation 64......Page 899
Sally Weisdorf-Schindele & Sarah Jane Schwarzenberg Nutritional Support of Hematopoietic Cell Recipients 65......Page 909
Jonathan R. Gavrin & F. Peter Buckley Pain Management 66......Page 920
Mark M. Schubert, Douglas E. Peterson & Michele E. Lloid Oral Complications 67......Page 937
Jean E. Sanders Growth and Development after Hematopoietic Cell Transplantation 68......Page 955
Mary E.D. Flowers Deeg Delayed Complications after Hematopoietic Cell Transplantation 69......Page 970
Smita Bhatia & Ravi Bhatia Secondary Malignancies after Hematopoietic Cell Transplantation 70......Page 988
Section 5 Allogeneic Transplantation for Acquired Diseases......Page 1005
George E. Georges & Rainer Storb Allogeneic Hematopoietic Cell Transplantation for Aplastic Anemia 71......Page 1007
Robert P. Witherspoon Allogeneic Transplantation for Paroxysmal Nocturnal Hemoglobinuria 72......Page 1028
Frederick R. Appelbaum Allogeneic Transplantation for Chronic Myeloid Leukemia 73......Page 1033
Robert A. Krance Hematopoietic Cell Transplantation for Juvenile Myelomonocytic Leukemia 74......Page 1044
Keith E. Stockerl-Goldstein & Karl G. Blume Allogeneic Hematopoietic Cell Transplantation for Adult Patients with Acute Myeloid Leukemia 75......Page 1051
David A. Margolis & James T. Casper Allogeneic Transplantation for Acute Myeloid Leukaemia in Children 76......Page 1066
Stephen J. Forman Allogeneic Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia in Adults 77......Page 1081
Stella M. Davies, Norma K.C. Ramsey & John H. Keresy Allogeneic Transplantation for Acute Lymphoblastic Leukemia in Children 78......Page 1093
Jeanne E. Anderson Allogeneic Transplantation for Myelodysplastic and Myeloproliferative Disorders 79......Page 1110
David G. Maloney & Gösta Gahrton Allogeneic Hematopoietic Cell Transplantation for Multiple Myeloma 80......Page 1122
Issa Khouri & Richard Champlin Allogeneic Transplantation for Lymphoma and Chronic Lymphocytic Leukemia 81......Page 1131
Claudio Anasetti & Andrea Velardi Hematopoietic Cell Transplantation from HLA Partially Matched Related Donors 82......Page 1142
Effie W. Petersdorf Hematopoietic Cell Transplantation from Unrelated Donors 83......Page 1158
Robert H. Collins, Jr Management of Relapse after Allogeneic Transplantation 84......Page 1176
Brenda M. Sandmaier & Rainer Storb Nonmyeloablative Therapy and Hematopoietic Cell Transplantation for Hematologic Disorders 85......Page 1190
Richard W. Childs & Ramaprasad Srinivasan Allogeneic Hematopoietic Cell Transplantation for Solid Tumors 86......Page 1203
Section 6 Autologous Transplantation for Acquired Diseases......Page 1215
Philip J. Bierman & Auayporn Nademanee Autologous and Allogeneic Hematopoietic Cell Transplantation for Hodgkin’s Disease 87......Page 1217
Sandra J. Horning & James O. Armitage Autologous Hematopoietic Cell Transplantation for Non-Hodgkin’s Lymphoma 88......Page 1233
Anthony S. Stein & Stephen J. Forman Autologous Hematopoietic Cell Transplantation for Acute Myeloid Leukemia 89......Page 1247
Charles A. Linker Autologous Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia 90......Page 1264
Ravi Bhatia & Philip B. McGlave Autologous Hematopoietic Cell Transplantation for Chronic Myeloid Leukemia 91......Page 1276
Laurence Catley & Kenneth Anderson Autologous Hematopoietic Cell Transplantation for Multiple Myeloma 92......Page 1288
Raymond L. Comenzo & Morie A. Gertz Autologous Hematopoietic Cell Transplantation for AL Amyloidosis 93......Page 1309
Karen H. Antman Hematopoietic Cell Transplantation for Breast Cancer 94......Page 1324
Brandon Hayes-Lattin & Craig R. Nichols Hematopoietic Cell Transplantation in Germ Cell Tumors 95......Page 1334
Patrick J. Stiff Hematopoietic Cell Transplantation in Ovarian Carcinoma 96......Page 1346
Katherine K. Matthay Hematopoietic Cell Transplantation for Neuroblastoma 97......Page 1359
Ira J. Dunkel & Jonathan L. Finlay Hematopoietic Cell Transplantation for Brain Tumors 98......Page 1371
Allen R. Chen & Curt I. Civin Hematopoietic Cell Transplantation for Pediatric Patients with Solid Tumors 99......Page 1380
John A. Zaia, J. Scott Cairns & John J. Rossi AIDS and Hematopoietic Transplantation: HIV Infection, AIDS Lymphoma and Gene Therapy 100......Page 1395
Alan Tyndall & Alois Gratwohl Hematopoietic Stem Cell Transplantation for Autoimmune Diseases 101......Page 1411
Robert S. Negrin Prevention and Therapy of Relapse following Autologous Hematopoietic Cell Transplantation 102......Page 1420
Section 7 Allogenic Transplantation for Inherited Disease......Page 1433
Guido Lucarelli & Reginald A. Clift Marrow Transplantation in Thalassemia 103......Page 1435
Mark C. Walters Hematopoietic Cell Transplantation for Sickle Cell Disease 104......Page 1443
Trudy N. Small, Wilhelm Friedrich & Richard J. O’Reilly Hematopoietic Cell Transplantation for Immunodeficiency Diseases 105......Page 1456
Peter F. Coccia Hematopoietic Cell Transplantation for Osteopetrosis 106......Page 1469
Charles Peters Hematopoietic Cell Transplantation for Storage Diseases 107......Page 1481
Rajni Agarwal Hematopoietic Cell Transplantation for Macrophage and Granulocyte Disorders 108......Page 1497
John E. Wagner, Margaret L. MacMillan & Arleen D. Auerbach Hematopoietic Cell Transplantation for Fanconi Anemia 109......Page 1509
Section 8 The Future......Page 1531
Ernest Beutler Hematopoietic Cell Transplantation in the 21st Century 110......Page 1533
Index......Page 1537