Therapeutics of Parkinson's Disease and Other Movement Disorders

Cover......Page 1
Therapeutics of Parkinson\'s Disease and Other Movement Disorders......Page 2
Front Matter......Page 3
Copyright......Page 4
Contents......Page 6
Preface......Page 10
Contributors......Page 12
Part I - PARKINSON’S DISEASE AND PARKINSONISM......Page 18
The Etiopathogenesis of Parkinson’s Disease: Basic Mechanisms of Neurodegeneration......Page 19
Physiology of Parkinson’s Disease......Page 41
Pharmacology of Parkinson’s Disease......Page 53
The Treatment of Early Parkinson’s Disease......Page 65
Treatment of Motor Complications in Advanced Parkinson’s Disease......Page 87
Managing the Non-Motor Symptoms of Parkinson’s Disease......Page 107
Surgery for Parkinson’s Disease......Page 137
Future Cell- and Gene-Based Therapies for Parkinson’s Disease......Page 161
Parkinson-Plus Disorders......Page 173
Part II - TREMOR DISORDERS......Page 194
Essential Tremor......Page 195
Other Tremor Disorders......Page 209
Part III - DYSTONIA, CRAMPS, AND SPASMS......Page 220
Pathophysiology of Dystonia......Page 221
General Management Approach to Dystonia......Page 233
Botulinum Toxin for Treatment of Dystonia......Page 243
Surgical Treatments of Dystonia......Page 257
Wilson’s Disease......Page 267
Cramps and Spasms......Page 279
Stiff Person Syndrome......Page 299
Part IV - CHOREA, TICS AND OTHER MOVEMENT DISORDERS......Page 310
Huntington’s Disease......Page 311
Chorea......Page 333
Treatment of Tics and Tourette Syndrome......Page 347
Therapeutics of Paroxysmal Dyskinesias......Page 361
Treatment of Miscellaneous Disorders......Page 369
Myoclonus......Page 379
Part V - DRUG-INDUCED MOVEMENT DISORDERS......Page 388
Neuroleptic-Induced Movement Disorders......Page 389
Other Drug-Induced Dyskinesias......Page 405
Part VI - ATAXIA AND DISORDERS OF GAITAND BALANCE......Page 422
Ataxia......Page 423
Treatment of Gait and Balance Disorders......Page 433
Part VII - RESTLESS LEGS SYNDROME......Page 462
The Restless Legs Syndrome......Page 463
Part VIII - PEDIATRIC MOVEMENT DISORDERS......Page 486
Pediatric Movement Disorders......Page 487
Part IX - PSYCHOGENIC MOVEMENT DISORDERS......Page 494
Psychogenic Movement Disorders......Page 495
Index......Page 505