The Skeleton

Front Matter....Pages i-xviii
Front Matter....Pages 1-1
Molecular Basis of Cell—Cell Interaction and Signaling in Mesenchymal Chondrogenesis....Pages 3-15
Chondrocyte Cell Fate Determination in Response to Bone Morphogenetic Protein Signaling....Pages 17-42
Regulation of Chondrocyte Differentiation....Pages 43-53
Continuous Expression of Cbfa1 in Nonhypertrophic Chondrocytes Uncovers Its Ability to Induce Hypertrophic Chondrocyte Differentiation and Partially Rescues Cbfa1-Deficient Mice....Pages 55-75
Molecular Biology and Biosynthesis of Collagens....Pages 77-87
Mechanotransduction Pathways in Cartilage....Pages 89-98
Front Matter....Pages 99-99
Molecular Genetic Analysis of the Role of the HoxD Complex in Skeletal Development....Pages 101-112
Control of Development and Homeostasis Via Regulation of BMP, Wnt, and Hedgehog Signaling....Pages 113-130
FGF4 and Skeletal Morphogenesis....Pages 131-145
Retinoid Signaling and Skeletal Development....Pages 147-157
Retinoids and Indian Hedgehog Orchestrate Long Bone Development....Pages 159-170
Front Matter....Pages 171-171
Synergy Between Osteogenic Protein-1 and Osteotropic Factors in the Stimulation of Rat Osteoblastic Cell Differentiation....Pages 173-183
Bone Morphogenic Proteins, Osteoblast Differentiation, and Cell Survival During Osteogenesis....Pages 185-193
Osteoclast Differentiation....Pages 195-213
Front Matter....Pages 215-215
Soluble Signals and Insoluble Substrata....Pages 217-227
Perichondrial and Periosteal Regulation of Endochondral Growth....Pages 229-247
Computer Simulations of Cancellous Bone Remodeling....Pages 249-261
Effects of Microgravity on Skeletal Remodeling and Bone Cells....Pages 263-276
Front Matter....Pages 277-277
Quantitative Analyses of the Development of Different Hard Tissues....Pages 279-292
Fetal Mineral Homeostasis and Skeletal Mineralization....Pages 293-306
Front Matter....Pages 277-277
Control of Osteoblast Function and Bone Extracellular Matrix Mineralization by Vitamin D....Pages 307-332
Front Matter....Pages 333-333
Role of Pax3 and PDGF-α Receptor in Skeletal Morphogenesis and Facial Clefting....Pages 335-347
Genetics of Achondroplasia and Hypochondroplasia....Pages 349-359
Effects of Boric Acid on Hox Gene Expression and the Axial Skeleton in the Developing Rat....Pages 361-372
Toxicant-Induced Lumbar and Cervical Ribs in Rodents....Pages 373-383
Experimental Skeletal Dysmorphology....Pages 385-413
Back Matter....Pages 415-428