The Pilot Plant Real Book A Unique Handbook for the Chemical Process Industry

1 The Pilot Plant
Role of the Plant · Factors in Scale-Up · Some Do's and Don'ts · Tips for Developing Scalable
Reactions · Calorimetry/Safety Screening · Haz-Ops · Flow Diagrams · Batch Records · GMP 
2 Equipment and Operations 
Equipment Train · Reactors · Agitation · Raw Material Charging · Reaction Control · Sampling
• Workup · Distillation · Crystallization · Isolation/Filtration · Drying · Equipment Cleaning 
3 Liquid Handling 
Pumps · Pump Sizing, Selection and Troubleshooting · Pipes, Fittings and Valves · Flanges and
Gaskets · Hose · Friction and Viscosity Effects · O-rings · Stoppers · Liquid Storage Vessels 
4 Heat Transfer 
Heat Transfer in Stirred Vessels · Heat Exchangers · Temperature Control Units · Heat Transfer
Fluid Selection and Properties · Glycols and Brines · Steam · Process Chillers 
5 Electricity and Instrumentation 
Electrical Safety · Electric Power Basics · Receptacle Types · Electrical Enclosure Data ·
Intrinsic Safety · Motors · Temperature, Pressure and pH Measurement · Process Control Basics 
6 Solvents 
Safe Handling · Properties and Selection · Solubility Map · Temperature/Vapor Pressure Rela­
tionships · Distillation · Binary Azeotropes · Ternary Water-Containing Azeotropes · Water Data 
7 Compressed Gases 
Safe Handling · Physical Properties · Cryogenic Liquids · Cylinder Specifications · Connection
Data · Pressure Regulators · Gas Metering · Air Data · Air Compressors · Vacuum Systems 
8 Chemical Data 
Properties of Acids and Bases · Dilutions · pKas · pH Buffers · Color Indicators · Aqueous
Solubility Data · Aqueous Solution Density · Organic Functional Groups · Reaction Types 
9 Chemical Hygiene and Safety 
Safe Handling of Chemicals · MSDSs · Hazards Classifications · Labeling · Fire Safety ·
Personal Protective Equipment · Glove Selection · Respirators · Incompatible Chemicals 
10 Materials Selection 
Properties of Elastomers, Plastics, Metals and Glass · Metallic Corrosion Data · Glass Corrosion
• Material Compatibility Table 
11 Miscellaneous 
Unit Conversion Tables · Physical Constants · Mathematical Relationships · Geometric Formu­
las · Temperature/Pressure Conversion Charts · Cold Mixtures · Sieve Sizes · Agency Acronyms 
Bibliography
Additional Recommended Reading
Index