The histiocyte and it’s role in dermatology

THE HISTIOCYTE AND IT’S ROLE IN DERMATOLOGY
INTRODUCTION
HISTIOCYTES
LANGERHANS CELLS
SITES
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REGIONAL VARIATION
EMBRYOLOGY
SOURCE
HISTOLOGY
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MARKERS
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ELECTRON MICROSCOPY
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FUNCTIONS
EVENTS DURING ANTIGEN TRAPPING
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CLASSIFICATION OF HISTIOCYTOSIS: HISTIOCYTE SOCIETY
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L GROUP
LANGERHANS CELL HISTIOCYTOSES (LCH)
AGE
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GENETICS
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PRESENTATION
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SKIN LCH IN ADULTS
SKIN – ONLY LCH
SKIN LCH AS PART OF LOW RISK MS DISEASE
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SKIN AS PART OF DISSEMINATED DISEASE
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EXTRACUTANEOUS FINDINGS
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DIFFERENTIAL DIAGNOSIS
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JUVENILE XANTHOGRANULOMA (JXG)
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CLINICAL FEATURES: JXG
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CLINICAL FEATURES: JXG (2)
HISTOPATHOLOGY: JXG
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IMMUNOHISTOCHEMISTRY
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PROGNOSIS AND TREATMENT: JXG
RETICULOHISTIOCYTOMA
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BENIGN CEPHALIC HISTIOCYTOSIS
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GENERALISED ERUPTIVE HISTIOCYTOMA
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PROGRESSIVE NODULAR HISTIOCYTOSIS
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ROSAI-DORFMAN DISEASE
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NECROBIOTIC XANTHOGRANULOMA
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TREATMENT
XANTHOMA DISSEMINATUM
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TREATMENT
MULTICENTRIC RETICULOHISTIOCYTOSIS
Slide 92
HISTOPATHOLOGY
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PROGNOSIS AND TREATMENT
HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS
Slide 97
TREATMENT (2)
DIFFUSE PLANE XANTHOMATOSIS
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TREATMENT (3)
MALAKOPLAKIA
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FAMILIAL SEA-BLUE HISTIOCYTOSIS
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HEREDITARY PROGRESSIVE MUCINOUS HISTIOCYTOSIS
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