The Genetics of Coeliac Disease

Front Matter....Pages i-xxxi
Front Matter....Pages 1-1
Epidemiological Investigation....Pages 3-6
Factors in the Epidemiology of Coeliac Disease in the West of Ireland....Pages 7-14
Prevalence of Coeliac Disease in Derby....Pages 15-17
Incidence and Age Distribution of Coeliac Disease in North-Eastern Switzerland....Pages 19-22
On the Incidence of Coeliac Disease in Austria: A Study Comprising a Nine-year Period....Pages 23-27
The Changing Clinical Picture of Coeliac Disease in Lothian, Scotland....Pages 29-40
A Recent Reduction in the Incidence of Childhood Coeliac Disease in the West of Scotland....Pages 41-45
Recent Scandinavian Data on the Epidemiology of Coeliac Disease....Pages 47-50
Discussion of Chapters 1–8....Pages 51-64
Membership of the Coeliac Society of the United Kingdom....Pages 65-69
Malignant and Non-Malignant Diseases in Relatives of Patients with Dermatitis Herpetiformis and Coeliac Disease: A Preliminary Report....Pages 71-84
On the Association of Coeliac Disease with Allergic Disorders. A Study of Family Histories of 110 Families with One or Two Children with Coeliac Disease....Pages 85-94
Epidemiological and Genetic Aspects of the Coeliac Syndrome in Relation to Dermatitis Herpetiformis....Pages 95-102
Coeliac Disease in Asian Children in the United Kingdom....Pages 103-108
Front Matter....Pages 109-109
The HLA System....Pages 111-121
Evolution and the Genetics of Coeliac Disease....Pages 123-128
Chido and Rodgers Blood Groups....Pages 129-135
C4 and Factor Bf Polymorphisms in Coeliac Disease....Pages 137-141
HLA-DR Antigens in Coeliac Disease. A Population and Multiple Case Family Study....Pages 143-152
B-Cell Alloantigens Associated with Coeliac Disease in the West of Ireland....Pages 153-160
Front Matter....Pages 109-109
DR Locus-Controlled B-Cell Alloantigens in Coeliac Disease in The Netherlands....Pages 161-171
The Relationship of HLA-A, B Status to the Clinical Findings and Autoimmunity in Coeliac Disease....Pages 173-182
The Influence of Histocompatibility Genes on the Pathogenesis of Gluten Sensitive Enteropathy....Pages 183-193
Front Matter....Pages 195-195
Coeliac Disease: Previous Family Studies....Pages 197-200
A Critical Analysis of HLA in Coeliac Family Studies in Birmingham....Pages 201-206
The Familial Occurrence of Coeliac Disease....Pages 207-209
Gluten Sensitive Enteropathy in Spain: Genetic and Environmental Factors....Pages 211-234
The Familial Incidence of Asymptomatic Coeliac Disease....Pages 235-250
Investigations of a Two-Locus Model for Coeliac Disease....Pages 251-264
Liverpool Coeliac Family Study....Pages 265-290
Summing-up....Pages 291-293
Back Matter....Pages 295-301