The Cholinergic Synapse

Content: 
Edited by
Page iii

Copyright page
Page iv

Preface
Page v
Stanislav Tuček

List of Contributors
Pages vii-xiii

Abbreviations
Pages xv-xvi

The Ultrastructure of Autonomic Cholinergic Nerves and Junctions Original Research Article
Pages 3-21
G. Burnstock

The Importance of Axonal Transport and Endoplasmic Reticulum in the Function of Cholinergic Synapse in Normal and Pathological Conditions Original Research Article
Pages 23-44
B. Droz, H.L. Koenig, L. Di Giamberardino, J.Y. Couraud, M. Chretien, F. Souyri

Recent Progress in the Biochemistry of Choline Acetyltransferase Original Research Article
Pages 45-58
D. Malte-Sørenssen

Immunohistochemistry of Choline Acetyltransferase Original Research Article
Pages 59-70
E.G. Mcgeer, P.L. Mcgeer, T. Hattori, V.K. Singh

Sodium-Dependent High Affinity Choline Uptake Original Research Article
Pages 71-76
Michael J. Kuhar

Relationship of Choline Uptake to Acetylcholine Synthesis and Release Original Research Article
Pages 77-88
R.M. Marchbanks, S. Wonnacott

Choline Uptake and Metabolism by Nerve Cell Cultures Original Research Article
Pages 89-96
R. Massarelli, Tuen Yee Wong, Chantal Froissart, J. Robert

Regulation of Acetylcholine Synthesis in Cholinergic Nerve Terminals Original Research Article
Pages 97-106
Guillermo Pilar, Ken Vaca

Cholinergic False Transmitters Original Research Article
Pages 107-121
B. Collier, P. Boksa, S. Lovat

On the Mechanism of Acetylcholine Release Original Research Article
Pages 125-139
M. Israël, Y. Dunant

Vesicular Heterogeneity and Turnover of Acetylcholine and ATP in Cholinergic Synaptic Vesicles Original Research Article
Pages 141-151
H. Zimmermann

Role of Vesicle Recycling in Vesicular Storage and Release of Acetylcholine in Torpedo Electroplaque Synapses Original Research Article
Pages 153-162
J.B. Suszkiw, V.P. Whittaker

Vesicular Storage and Release of Cholinergic False Transmitters Original Research Article
Pages 163-174
I. Von Schwarzenfeld, G. Sudlow, V.P. Whittaker

Facilitation, Augmentation, and Potentiation of Transmitter Release Original Research Article
Pages 175-182
K.L. Magleby

The Regulatory Role of Membrane Na+-K+-ATPase in Non-Quantal Release of Transmitter at the Neuromuscular Junction Original Research Article
Pages 183-189
František Vyskočil

Stimulation of Cholinergic Synaptosomes Isolated fkom Torpedo Electric Organ Original Research Article
Pages 191-202
N. Morel, M. Israël, R. Manaranche, B. Lesbats

Dual Effect of Noradrenaline on Cholinergic Transmission in Guinea-pig Ileum Original Research Article
Pages 203-209
Ondrěj Kadlec, Karel Mašek

Drug-Receptor Interaction at the Frog Neuromuscular Junction Original Research Article
Pages 213-223
F. Dreyer, K. Peper, R. Sterz, R.J. Bradley, K.-D. Müller

The Time Course of Postsynaptic Currents in Fast and Slow Junctions and its Alteration by Cholinesterase Inhibition Original Research Article
Pages 225-240
L.G. Magazanik, V.V. Fedorov, V.A. Snetkov

Activation of Acetylcholine Receptors in Mammalian Sympathetic Ganglion Neurones Original Research Article
Pages 241-252
A.A. Selyanko, V.I. Skok

Acetylcholine as an Excitatory and Inhibitory Transmitter in the Mammalian Central Nervous System Original Research Article
Pages 253-266
J.S. Kelly, Jane Dodd, R. Dingledine

Studies on a False Transmitter at the Neuromuscular Junction Original Research Article
Pages 267-275
W.A. Large, H.P. Rang

The Nicotinic Acetylcholine Receptor from Torpedo Electroplax Original Research Article
Pages 279-291
R.D. O'Brien, Katumi Sumikawa, R.E. Gibson

Acetylcholine Receptor of Limnaea Stagnalis Neurones. Study of the Active Site Functional Groups Original Research Article
Pages 293-302
Catherine A. Vulfius, Olga P. Yurchenko, V.I. Il'In, P.D. Bregestovski, B.N. Veprintsev

Biochemical Characterization of Muscarinic Receptors: Multiplicity of Binding Components Original Research Article
Pages 303-311
Jean Massoulié, Susan Carson, Gabor Kato

Cholinesterases of the Motor End-Plate of the Rat Diaphragm Original Research Article
Pages 313-322
Miro Brzin, Tomaž Kiauta

The Life History of Acetylcholine Receptors Original Research Article
Pages 325-334
Douglas M. Fambrough, Peter N. Devreotes, John M. Gardner, Diana J. Card

Accumulation of Acetylcholine Receptors at Nerve-Muscle Contacts in Culture Original Research Article
Pages 335-349
M.W. Cohen, M.J. Anderson, E. Zorychta, P.R. Weldon

Morphogenesis of the Cholinergic Synapse in Striated Muscle Original Research Article
Pages 350,352-358
Juhani Juntunen

Elimination of Inappropriate Nerve-Muscle Connections During Development of Rat Embryos Original Research Article
Pages 359-364
M.J. Dennis, A.J. Harris

The Elimination of Polyneuronal Innervation of End-Plates in Developing Rat Muscles with Altered Function Original Research Article
Pages 365-372
Jiřina Zelená, F. Vyskočil, Isa Jirmanová

Competitive Interactions between Developing Cholinergic Neurones Original Research Article
Pages 373-384
Lynn T. Landmesser

Studies on Neurotrophic Regulation of Skeletal Muscle Original Research Article
Pages 385-390
S. Thesleff

Factors Affecting the Distribution of Acetylcholine Receptors in Innervated and Denervated Skeletal Muscle Fibres Original Research Article
Pages 391-402
Rosemary Jones

A Histological and Electrophysiological Study of the Effects of Colchicine on the Frog Sartorius Nerve-Muscle Preparation Original Research Article
Pages 403-410
E.M. Volkov, G.I. Poletaev, E.G. Ulumbekov, Kh.S. Khamitov

The Effect of Altered Function of Dopaminergic Neurones on the Cholinergic System in the Striatum Original Research Article
Pages 411-419
H. Ladinsky, S. Consolo

The Immunopathological Basis of Acetylcholine Receptor Deficiency in Myasthenia Gravis Original Research Article
Pages 423-434
Andrew G. Engel

The Role of Humoral Immunity in Myasthenia Gravis Original Research Article
Pages 435-440
Anne D. Zurn, Bernard W. Fulpius

Humoral Immunity in Myasthenia Gravis: Relationship to Disease Severity and Steroid Treatment Original Research Article
Pages 441-448
R.J. Bradley, D. Dwyer, B.J. Morley, G. Robinson, G.E. Kemp, S.J. Oh

Acetylcholine in Intercostal Muscle from Myasthenia Gravis Patients and in Rat Diaphragm after Blockade of Acetylcholine Receptors Original Research Article
Pages 449-458
P.C. Molenaar, R.L. Polak, R. Miledi, S. Alema, A. Vincent, J. Newsom-Davis

Short Review of Progress in Experimental: yasthenia Gravis, Bearing on the Pathogenesis of Myasthenia Gravis Original Research Article
Pages 459-463
Edith Heilbronn

The Effects of Inorganic Lead on Cholinergic Transmission Original Research Article
Pages 465-470
Alan M. Goldberg

Development of Cholinergic Enzymes in the Brain of Normal and Hypertensive Rats
Page 471
J. Bagjar, V. Hrdina, V. Golda

Release of Acetylcholine from a Vascular Perfused Hemidiaphragm – Phrenic Nerve Preparation
Pages 471-472
G. Bierkamper

Cholinergic Mechanisms in the Visual System of Rat
Page 472
V. Bigl, H. Wenk, U. Meyer, H.-J. Lüth

Low Ionic Strength Aggregation and Collagenase Sensitivity of Some Acetylcholinesterase Molecular Forms from Avian and Mammalian Tissues
Pages 472-473
S. Bon, J. Massoulié

Exo-endocytosis at Neuromuscular Junctions during Intense Quantal Release of Neurotransmitter
Page 473
B. Ceccarelli, F. Grohovaz, W.P. Hurlbut

Relationship between the Steady-State Choline Level in Plasma and the Acetylcholine Level in Rat Brain Areas
Page 474
S. Consolo, H. Ladinsky, R. Gomeni

Acetylcholinesterase Forms in Dystrophic Chickens. Normal Axonal Transport in Peripheral Nerves, Abnormal Concentration in Fast Twitch Muscles and Plasma
Pages 474-475
L. Di Giamberardino, J. Lyles, J.Y. Couraud, I. Silman, E.A. Barnard

Biochemical Effects of Presynaptic Snake Neurotoxins on Cholinergic Nerve Terminals
Pages 475-476
M.J. Dowdall

Involvement of Thiamine in Synaptic Transmission
Page 476
L. Eder, Y. Dunant, M. Baumann, L. Servetiadis

Interactions of cholinergic drugs, GABA and Cyclic GMP in Picrotoxin Induced Convulsions
Pages 476-477
V.P. Georgiev, N.D. Lambadjieva

Cytochemical Studies of Enzymes Located at the Neuromuscular Junction in the Course of Denervation
Page 477
Jolanta Godlewska-Jdrzejczyk

Blood Cholinergic Parameters as a Potential Index of Central Cholinergic Function
Page 478
I. Hanin, U. Kopp, C. Nevar, D.C. Spiker, J.F. Neil, D.J. Kupfer

Ultrastructure of the Cholinergic Synapse Revealed by Quick-Freezing
Pages 478-481
John E. Heuser, Shelley R. Salpeter

Yawning: A Central Cholinergic Response under Monoaminergic Modulation
Page 482
B. Holmgren, R. Urbá-Holmgren

Control of Transmitter Release during Repetitive Activation of Motor Nerve Terminals
Pages 482-483
M.A. Kamenskaya

Multiple Molecular Forms of Acetylcholinesterase
Page 483
P. Kása, L. Lehotai

Tissue Differences in the Effect of Atropine on the Evoked Release of Acetylcholine
Pages 483-484
H. Kilbinger

Influence of Neurones and Contractile Activity on Acetylcholinesterase and Acetylcholine Receptors in Muscle Cell Cultures
Page 484
J. Koenig, M. Vigny

Miniature End-Plate Potentials are Composed of Subunits
Pages 484-485
M.E. Kriebel, F. Llados, D.R. Matteson

Choline Uptake, Acetylcholine Synthesis and Release in Synaptosomes from Hypoxic Rat Brain
Page 485
H.J. Ksiżaak

Drug-Induced Decremental Oscillations following Spike Potential in Cat Sympathetic Ganglion
Page 486
J. Machová

Modulation of Acetylcholine Turnover Rate by Neuropeptides
Pages 486-487
D. Malthe-Sørensen, P. Wood

Source of Choline for Acetylcholine Synthesis in the Brain
Page 487
Stephen P. Mann

Regeneration of Rat Neuromuscular Synapses
Page 488
S. Manolov

Effect of Calcium Ionophores on Acetylcholine Output from Rat Brain Slices
Page 488
P. Mantovani, G. Pepeu

The Mechanism of the Trophic Action of Acetylcholine
Page 489
A.M. Mustafin

Biochemical Characterization of Synaptic Vesicles Isolated from Guinea-pig Cerebral Cortex
Page 489
Á. Nagy, Z. Rakonczay, T. Farkas, L. Keszthelyi

Neuronal Control in Tonic Muscle Fibres
Pages 489-490
G.A. Nasledov, T.L. Radzyukevich

Relation between Acetylcholine Turnover and High Affinity Choline Uptake in Discrete Brain Regions
Page 490
A. Nordberg, A. Sundwall

Regional Biosynthesis of Acetylcholine in the Brain of Rat Following Chronic Treatment with Barbital
Pages 490-491
A. Nordberg, G. Wahlström

Cytochemical Localization of Choline Acetyltransferase
Page 491
W. Ovtscharoff

The Effect of Long-Time Curarization on the Frog Neuromuscular Junction
Pages 491-492
M. Pécot-Dechavassine, A. Wernig

Cholinergic (Nicotinic) Receptor and Lipids: Lipid Composition of Receptor-Rich Membranes Purified from Torpedo murmorata Electric Organ and Interaction of the Purified Receptor Protein with Monolayers of Pure Lipids
Page 492
J.L. Popot, R.A. Demel, A. Sobel, L.L.M. Van Deenen, J.P. Changeux

The Effect of Hemicholinium-3 on the Turnover of Acetylcholine in the Auerbach Plexus of Guinea-pig Ileum and in the Vas Deferens of Rat
Pages 492-493
G.T. Somogyi

Pharmacologically Induced Stimulus-Bound Repetition (SBR) in Frog Sympathetic Ganglion
Page 493
S. àtolc

Kinetics of Synthesis, Storage and Release of Acetylcholine in the Myenteric Plexus of the Guinea-pig
Pages 493-494
J.C. Szerb

ATP-Citrate Lyase in the Cholinergic System of Rat Brain
Page 494
A. Szutowicz, W. Lysiak, S. Angielski

Postsynaptic Muscarinic Receptor and Sodium-Pump Activity
Page 495
T.L. Török, E.S. Vizi

Effects of Scopolamine and Pilocarpine on the Activity of Acetylcholinesterase in Rat Brain Synaptosomal Fractions
Page 495
L. Venkov, N. Iancheva

Non-Specific Cholinesterase and Acetylcholinesterase Molecular Forms in Rat Tissues
Page 496
M. Vigny, V. Gisiger, J. Massoulié

A Search for the Factor in Peripheral Nerves Which Induces Acetylcholine Sensitivity of Skeletal Muscle
Page 496
F. Vyskočil, I. Syrový

Cholinergic Projections to the Cortex of the Rat Brain
Page 497
H. Wenk, V. Bigl, U. Meyer

Differences in Transmitter Release at Different Synapses of the Frog Sartorius Muscle
Page 497
L.N. Zefirov, A.L. Zefirov

Author Index
Pages 499-500

Subject Index
Pages 501-511