The Biophysics of Organ Cryopreservation

Front Matter....Pages i-x
Front Matter....Pages 1-1
Organ Transplantation: The Role of Preservation....Pages 3-14
An Introduction to the Problems of Organ Cryopreservation....Pages 15-21
Front Matter....Pages 23-23
Biological Effects of Cryoprotectant Perfusion, Delivery and Removal to Nonfrozen Organs....Pages 25-49
Mass Transfer of Liquids Across Biological Barriers....Pages 51-78
Cytoplasmic Organisation and the Properties of Cell Water: Speculations on Animal Cell Cryopreservation....Pages 79-88
Heat Transfer during Cryopreservation....Pages 89-116
Ice Crystals in Tissues and Organs....Pages 117-140
Front Matter....Pages 141-141
Aqueous Solutions: Crystallization, Vitrification and Liquefaction....Pages 143-146
Crystallization and Vitrification in Cryoprotected Aqueous Systems....Pages 147-171
Ice Crystal Growth in Aqueous Solutions....Pages 173-199
Non-Equilibrium Formation of Ice in Aqueous Solutions: Efficiency of Polyalcohol Solutions for Vitrification....Pages 201-236
Devitrification and Recrystallization of Glass Forming Aqueous Solutions....Pages 237-263
Biological Effects of Vitrification and Devitrification....Pages 265-297
Front Matter....Pages 299-299
Electromagnetic Thawing of Organs: A Multidisciplinary Challenge....Pages 301-313
Electromagnetic Heating Techniques for Organ Rewarming....Pages 315-335
Tissue Heating: Applicator Types and Analysis by Phantom Models....Pages 337-366
The Design of an Electromagnetic Rewarming System for Cryopreserved Tissue....Pages 367-386
Heat Control and Sensing during Electromagnetic Recovery of Cryopreserved Large Organs....Pages 387-412
Front Matter....Pages 413-413
Freezing Patterns in Tissue by NMR Technology....Pages 415-429
Nuclear Magnetic Resonance (NMR) Imaging of Perfusion....Pages 431-444
Front Matter....Pages 413-413
Evaluation of Biochemical Processes by NMR....Pages 445-460
Examination of Organ Physiology by Positron Emission Tomography....Pages 461-476
Back Matter....Pages 477-485