The Benzodiazepines: Current Standards for Medical Practice

Front Matter....Pages i-ix
Introduction....Pages 1-3
Front Matter....Pages 5-5
The Biological Basis of Benzodiazepine Actions....Pages 7-41
Clinical Pharmacokinetics of the Benzodiazepines....Pages 43-58
Pharmacokinetic Considerations in the Treatment of Chronic Anxiety....Pages 59-64
Front Matter....Pages 65-65
An International Overview....Pages 67-86
Principles of Therapeutic Applications of Benzodiazepines....Pages 87-96
Benzodiazepines in Emotional Disorders....Pages 97-109
Anxiety....Pages 111-119
Clinical Comparison of Benzodiazepine Hypnotics With Short and Long Elimination Half-Lives....Pages 121-147
Seizure Disorders....Pages 149-157
Alcohol and Other Drug Withdrawals....Pages 159-162
Additional Clinical Uses of Benzodiazepines....Pages 163-166
Vital Uses of Diazepam in Third World Countries....Pages 167-175
Front Matter....Pages 177-177
Abuse and Dependency:An International Perspective....Pages 179-199
Experimental Abuse Liability Assessment of Benzodiazepines....Pages 201-207
Abuse Liability of Benzodiazepines:A Review of Human Studies Evaluating Subjective and/or Reinforcing Effects....Pages 209-225
Acute and Chronic Toxicity of Benzodiazepines....Pages 227-231
Front Matter....Pages 233-233
Benzodiazepine Dependency Syndromes....Pages 235-248
Front Matter....Pages 249-249
The Benzodiazepines:Public Health, Social and Regulatory Issues. An Industry Perspective....Pages 251-265
Benzodiazepines: International Legislation and Relation to the Convention on Psychotropic Substances 1971....Pages 267-285
Back Matter....Pages 287-313