Textbook of pharmacoepidemiology

Textbook of Pharmacoepidemiology......Page 4
Contents......Page 8
List of Contributors......Page 12
Preface......Page 16
Acknowledgments......Page 18
Acknowledgments from Pharmacoepidemiology, Fourth Edition......Page 20
Section I Introduction to Pharmacoepidemiology......Page 22
1 What is Pharmacoepidemiology?......Page 24
2 Study Designs Available for Pharmacoepidemiology Studies......Page 34
3 Sample Size Considerations for Pharmacoepidemiology Studies......Page 46
4 Basic Principles of Clinical Pharmacology Relevant to Pharmacoepidemiology Studies......Page 56
5 When Should One Perform Pharmacoepidemiology Studies?......Page 76
6 Views from Academia, Industry, and Regulatory Agencies......Page 84
Section II Sources of Pharmacoepidemiology Data......Page 110
7 Spontaneous Reporting in the United States......Page 112
8 Global Drug Surveillance: The WHO Programme for International Drug Monitoring......Page 138
9 Case–Control Surveillance......Page 158
10 Prescription-Event Monitoring......Page 172
11 Overview of Automated Databases in Pharmacoepidemiology......Page 188
12 Examples of Automated Databases......Page 194
13 Other Approaches to Pharmacoepidemiology Studies......Page 236
14 How Should One Perform Pharmacoepidemiology Studies? Choosing Among the Available Alternatives......Page 248
15 Validity of Pharmacoepidemiologic Drug and Diagnosis Data......Page 260
Section III Special Issues in Pharmacoepidemiology Methodology......Page 280
16 Bias and Confounding in Pharmacoepidemiology......Page 282
17 Determining Causation from Case Reports......Page 298
18 Molecular Pharmacoepidemiology......Page 308
19 Bioethical Issues in Pharmacoepidemiologic Research......Page 322
20 The Use of Randomized Controlled Trials for Pharmacoepidemiology Studies......Page 332
21 The Use of Pharmacoepidemiology to Study Beneficial Drug Effects......Page 342
22 Pharmacoeconomics: Economic Evaluation of Pharmaceuticals......Page 354
23 Using Quality-of-Life Measurements in Pharmacoepidemiologic Research......Page 366
24 The Use of Meta-analysis in Pharmacoepidemiology......Page 374
25 Patient Adherence to Prescribed Drug Dosing Regimens in Ambulatory Pharmacotherapy......Page 388
26 Novel Approaches to Pharmacoepidemiology Study Design and Statistical Analysis......Page 404
Section IV Special Applications of Pharmacoepidemiology......Page 418
27 Special Applications of Pharmacoepidemiology......Page 420
28 The Future of Pharmacoepidemiology......Page 468
Appendix A Sample Size Tables......Page 476
Appendix B Glossary......Page 494
Index......Page 502