Systems Biology: Volume II: Networks, Models, and Applications (Series in Systems Biology)

Contents......Page 10
Contributors......Page 12
Systems Biology: A Perspective......Page 16
1 Mass Spectrometry in Systems Biology......Page 28
2 Mathematical Modeling and Optimization Methods for De Novo Protein Design......Page 67
3 Molecular Simulation and Systems Biology......Page 92
4 Global Gene Expression Assays: Quantitative Noise Analysis......Page 128
5 Mapping the Genotype–Phenotype Relationship in Cellular Signaling Networks: Building Bridges Over the Unknown......Page 162
6 Integrating Innate Immunity into a Global “Systems” Context: The Complement Paradigm Shift......Page 194
7 Systems Biotechnology: Combined in Silico and Omics Analyses for the Improvement of Microorganisms for Industrial Applications......Page 218
8 Genome-Scale Models of Metabolic and Regulatory Networks......Page 257
9 Biophysical Models of the Cardiovascular System......Page 290
10 Embryonic Stem Cells as a Module for Systems Biology......Page 322
B......Page 344
C......Page 345
D......Page 346
E......Page 347
F......Page 348
G......Page 349
I......Page 350
M......Page 351
P......Page 355
R......Page 357
S......Page 358
Y......Page 359
Z......Page 360