Surgical Options for the Management of Congestive Heart Failure

Contents......Page 4
Surgical Options for the Management of Congestive Heart Failure......Page 5
Reference......Page 6
Introduction......Page 7
Aortic Stenosis......Page 8
Aortic Regurgitation......Page 11
References......Page 13
Introduction......Page 15
Anatomic and Functional Alterations......Page 16
Surgical Options for Valve Repair or Replacement......Page 17
Clinical and Therapeutic Correlates......Page 18
Conclusion......Page 19
References......Page 20
Introduction......Page 21
The European Coronary Surgery Study......Page 22
The Arterial Revascularization Therapies Study......Page 23
The Argentine Randomized Study......Page 24
The Coronary Angioplasty versus Bypass Revascularization Investigation......Page 25
Recent Clinical Series in Patients with Ventricular Dysfunction......Page 26
Conclusions......Page 27
References......Page 28
Myocardial ‘Stunning ’and ‘Hibernation’......Page 29
Evaluation of Myocardial Viability......Page 30
On-Pump CABG in Patients with Depressed LV Function......Page 31
Benefits of Off-Pump Surgery......Page 32
Off-Pump CABG in Patients with a ‘Poor Ventricle’......Page 33
The Tufts-New England Medical Center Off-Pump CABG Experience......Page 34
References......Page 35
Clinical Results......Page 37
Operative Technique......Page 38
Angina Class......Page 39
Myocardial Perfusion......Page 40
Long-Term Results......Page 41
Mechanisms of TMR......Page 42
Angiogenesis......Page 43
Conclusion......Page 44
References......Page 45
Introduction......Page 48
Surgical Ventricular Restoration......Page 49
Phase One Human Trials of Autologous Skeletal Myoblast CCM......Page 54
Stem Cells and Beyond......Page 57
References......Page 58
Introduction......Page 61
LV Reconstruction for Ischemic Cardiomyopathy......Page 62
Partial Left Ventriculectomy......Page 66
Conclusion......Page 69
References......Page 70
Introduction......Page 72
Clinical Trials of Permanent Biventricular Pacing......Page 73
Heart Failure Severity......Page 74
Baseline Rhythm......Page 75
Implantation Techniques and Technical Issues......Page 76
Conclusions......Page 77
References......Page 78
Predictors of Compromised Survival in CHF......Page 79
Indications for Transplant Listing......Page 80
Demographics......Page 81
Donor Identification......Page 82
Organ Allocation......Page 83
Graft Procurement and Techniques of Transplantation......Page 84
Rejection Grading and Surveillance......Page 85
Induction and Maintenance......Page 86
Prevention of Graft Vasculopathy......Page 87
Management of Pulmonary Hypertension......Page 88
Noninfectious Complications......Page 89
Fungal and Protozoal Infections......Page 90
Conclusions......Page 91
References......Page 92
Introduction......Page 93
Novacor Left Ventricular Assist System......Page 94
CardioWest Total Artificial Heart......Page 95
LVAD Implantation in Younger and Older Patients......Page 96
Potential for Recovery of the Failing Myocardium......Page 97
Time Course of Cardiac Recovery......Page 98
Future Perspectives on Cardiac Recovery......Page 99
Jarvik 2000 Heart......Page 100
References......Page 101
The HeartMate Left Ventricular Assist Device......Page 104
Arrow LionHeart LVAS......Page 106
The HeartMate II......Page 108
Conclusions......Page 109
References......Page 110
Introduction......Page 111
Implantation Technique......Page 112
United States......Page 113
Europe......Page 114
Discussion......Page 115
References......Page 116
Introduction......Page 117
Development and Design......Page 118
Implantation and Patient Management......Page 119
Conclusion......Page 120
References......Page 121
Introduction......Page 122
Lipid Metabolism......Page 123
Coagulation, Fibrinolysis and Endothelial Function......Page 124
Molecular Approaches for the Treatment of Atherosclerosis......Page 125
Hyperlipidemia......Page 126
Gene Therapy for Vein Graft Failure......Page 127
References......Page 128
Introduction......Page 131
Cellular and Molecular Biology of Angiogenesis......Page 133
Vascular Endothelial Growth Factor......Page 134
Angiogenic Delivery Strategies......Page 135
Clinical Angiogenesis Trials for Advanced Coronary Artery Disease......Page 137
Conclusions......Page 141
References......Page 142
Rationale for Cardiac Xenotransplantation......Page 144
Cellular Transplants......Page 145
Xenotransplantation......Page 146
Barriers to Xenotransplantation......Page 147
The Barriers to Xenotransplantation of Vascularized Organs......Page 148
Physiologic Hurdles to Xenotransplantation......Page 151
Prospects for Application......Page 152
References......Page 153
Subject Index Vol. 101, No. 1–3, 2004......Page 156