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ویرایش: نویسندگان: M Marshall, G Peat, E Nicholls, D van der Windt, H Myers, All authors سری: ISBN (شابک) : 9781405871600 ناشر: سال نشر: تعداد صفحات: 453 زبان: English فرمت فایل : PDF (درصورت درخواست کاربر به PDF، EPUB یا AZW3 تبدیل می شود) حجم فایل: 20 مگابایت
در صورت تبدیل فایل کتاب Subsets of symptomatic hand osteoarthritis in community-dwelling older adults in the United Kingdom: prevalence, inter-relationships, risk factor profiles and clinical characteristics at baseline and 3-years به فرمت های PDF، EPUB، AZW3، MOBI و یا DJVU می توانید به پشتیبان اطلاع دهید تا فایل مورد نظر را تبدیل نمایند.
توجه داشته باشید کتاب زیرمجموعههای استئوآرتریت علامتدار دست در افراد مسن ساکن جامعه در بریتانیا: شیوع، روابط متقابل، پروفایلهای عامل خطر و ویژگیهای بالینی در ابتدا و 3 سال نسخه زبان اصلی می باشد و کتاب ترجمه شده به فارسی نمی باشد. وبسایت اینترنشنال لایبرری ارائه دهنده کتاب های زبان اصلی می باشد و هیچ گونه کتاب ترجمه شده یا نوشته شده به فارسی را ارائه نمی دهد.
هدف: مقایسه شیوع جمعیت، روابط متقابل، پروفایلهای عوامل خطر و ویژگیهای بالینی زیرمجموعههای آرتروز علامتدار دست (OA) برای درک فراوانی و تمایز نسبی آنها. روش: 1076 بزرگسال ساکن جامعه با علائم دست (60 درصد زن، میانگین سنی 64.7 سال) انتخاب و با استفاده از معاینه فیزیکی در زیر مجموعههای از پیش تعریفشده طبقهبندی شدند و استاندارد شدند. عکسهای رادیوگرافی دست، نمرهگذاری شده با کلگرن
Objective: To compare the population prevalence,
inter-relationships, risk factor profiles and clinical
characteristics of subsets of symptomatic hand osteoarthritis
(OA) with a view to understanding their relative frequency and
distinctiveness. Method: 1076 community-dwelling adults with
hand symptoms (60% women, mean age 64.7 years) were recruited
and classified into pre-defined subsets using physical
examination and
standardised hand radiographs, scored with the Kellgren &
Lawrence (K&L) and Verbruggen-Veys grading systems. Detailed
information on selected risk factors was obtained from direct
measurement (Body Mass Index (BMI)), self-complete
questionnaires (excessive use of hands, previous hand injury)
and medical record review (hypertension, dyslipidaemia, type 2
diabetes). Hand pain and disability were self-reported at
baseline and 3-year follow-up using Australian/Canadian
Osteoarthritis Hand Index (AUSCAN). Results: Crude population
prevalence estimates for symptomatic hand OA subsets in the
adult population aged 50 years and over were: thumb base OA
(22.4%), nodal interphalangeal joint (IPJ) OA (15.5%),
generalised hand OA (10.4%), non-nodal IPJ OA (4.9%), erosive
OA (1.0%). Apart from thumb base OA, there was considerable
overlap between the subsets. Erosive OA appeared the most
distinctive with the highest female: male ratio, and the most
disability at baseline and 3-years. A higher frequency of
obesity, hypertension, dyslipidaemia, and metabolic syndrome
was observed in this subset. Conclusion: Overlap in the
occurrence of hand OA subsets poses conceptual and practical
challenges to the pursuit of distinct phenotypes. Erosive OA
may nevertheless provide particular insight into the role of
metabolic and cardiovascular risk factors in the pathogenesis
of OA. Read
more...
Abstract: Objective: To compare the population prevalence,
inter-relationships, risk factor profiles and clinical
characteristics of subsets of symptomatic hand osteoarthritis
(OA) with a view to understanding their relative frequency and
distinctiveness. Method: 1076 community-dwelling adults with
hand symptoms (60% women, mean age 64.7 years) were recruited
and classified into pre-defined subsets using physical
examination and standardised hand radiographs, scored with the
Kellgren & Lawrence (K&L) and Verbruggen-Veys grading systems.
Detailed information on selected risk factors was obtained from
direct measurement (Body Mass Index (BMI)), self-complete
questionnaires (excessive use of hands, previous hand injury)
and medical record review (hypertension, dyslipidaemia, type 2
diabetes). Hand pain and disability were self-reported at
baseline and 3-year follow-up using Australian/Canadian
Osteoarthritis Hand Index (AUSCAN). Results: Crude population
prevalence estimates for symptomatic hand OA subsets in the
adult population aged 50 years and over were: thumb base OA
(22.4%), nodal interphalangeal joint (IPJ) OA (15.5%),
generalised hand OA (10.4%), non-nodal IPJ OA (4.9%), erosive
OA (1.0%). Apart from thumb base OA, there was considerable
overlap between the subsets. Erosive OA appeared the most
distinctive with the highest female: male ratio, and the most
disability at baseline and 3-years. A higher frequency of
obesity, hypertension, dyslipidaemia, and metabolic syndrome
was observed in this subset. Conclusion: Overlap in the
occurrence of hand OA subsets poses conceptual and practical
challenges to the pursuit of distinct phenotypes. Erosive OA
may nevertheless provide particular insight into the role of
metabolic and cardiovascular risk factors in the pathogenesis
of OA