Studies on Experimental Models

Front Matter....Pages i-xix
Front Matter....Pages 1-1
Role of Oxidative Stress and Targeted Antioxidant Therapies in Experimental Models of Diabetic Complications....Pages 3-38
Experimental Models of Oxidative Stress Related to Cardiovascular Diseases and Diabetes....Pages 39-60
Front Matter....Pages 61-61
Arachidonic Acid Metabolism and Lipid Peroxidation in Stroke: Alpha-Tocotrienol as a Unique Therapeutic Agent....Pages 63-90
Assessment of Oxidative Stress in the Brain of Spontaneously Hypertensive Rat and Stroke-Prone Spontaneously Hypertensive Rat Using by Electron Spin Resonance Spectroscopy....Pages 91-103
Small Heat Shock Proteins and Doxorubicin-Induced Oxidative Stress in the Heart....Pages 105-130
Oxidative Stress in Cardiovascular Disease: Potential Biomarkers and Their Measurements....Pages 131-156
 In vivo Imaging of Antioxidant Effects on NF-κB Activity in Reporter Mice....Pages 157-184
Front Matter....Pages 185-185
MPTP and Oxidative Stress: It’s Complicated!....Pages 187-209
Oxidative Stress in Alzheimer’s Disease: A Critical Appraisal of the Causes and the Consequences....Pages 211-220
Retinal Disturbances in Patients and Animal Models with Huntington’s, Parkinson’s and Alzheimer’s Disease....Pages 221-250
Stress Gene Deregulation in Alzheimer Peripheral Blood Mononuclear Cells....Pages 251-263
The Use of Gpx4 Knockout Mice and Transgenic Mice to Study the Roles of Lipid Peroxidation in Diseases and Aging....Pages 265-278
An Experimental Model of Myocardial and Cerebral Global Ischemia and Reperfusion....Pages 279-299
Front Matter....Pages 301-301
Neovascular Models of the Rabbit Eye Induced By Hydroperoxide....Pages 303-317
Purinergic Signaling Involved in the Volume Regulation of Glial Cells in the Rat Retina: Alteration in Experimental Diabetes....Pages 319-340
Front Matter....Pages 341-341
 Helicobacter pylori -Induced Oxidative Stress and Inflammation....Pages 343-370
Experimental Models for Ionizing Radiation Research....Pages 371-397
Experimental Models to Study Cigarette Smoke-Induced Oxidative Stress In Vitro and In Vitro in Preclinical Models, and in Smokers and Patients with Airways Disease....Pages 399-420
Exhaled Breath Condensate Biomarkers of Airway Inflammation and Oxidative Stress in COPD....Pages 421-440
Induction of Oxidative Stress by Iron/Ascorbate in Isolated Mitochondria and by UV Irradiation in Human Skin....Pages 441-465
Front Matter....Pages 341-341
Carbon Tetrachloride-Induced Hepatotoxicity: A Classic Model of Lipid Peroxidation and Oxidative Stress....Pages 467-480
Enhanced Urinary Excretion of Lipid Metabolites Following Exposure to Structurally Diverse Toxicants: A Unique Experimental Model for the Assessment of Oxidative Stress....Pages 481-495
Oxidative Stress in Animal Models with Special Reference to Experimental Porcine Endotoxemia....Pages 497-510
Models and Approaches for the Study of Reactive Oxygen Species Generation and Activities in Contracting Skeletal Muscle....Pages 511-519
Exercise as a Model to Study Interactions Between Oxidative Stress and Inflammation....Pages 521-529
Exercise as a Model to Study Oxidative Stress....Pages 531-542
Front Matter....Pages 543-543
Models of Mitochondrial Oxidative Stress....Pages 545-562
Protection of Oxidant-Induced Neuronal Cells Injury by a Unique Cruciferous Nutraceutical....Pages 563-577
Oxidatively Generated Damage to DNA and Biomarkers....Pages 579-604
Measuring Oxidative Stress in Cell Cultures, Animals and Humans: Analysis and Validation of Oxidatively Damaged DNA....Pages 605-620
The Roles of cAMP and G Protein Signaling in Oxidative Stress-Induced Cardiovascular Dysfunction....Pages 621-635
Cellular and Chemical Assays for Discovery of Novel Antioxidants in Marine Organisms....Pages 637-657
Arsenic-Induced Oxidative Stress: Evidence on In Vitro Models of Cardiovascular, Diabetes Mellitus Type 2 and Neurodegenerative Disorders....Pages 659-680
Back Matter....Pages 681-698