Skin Lymphoma: The Illustrated Guide

Half Title......Page 2
Title Page......Page 3
Copyright......Page 4
Dedication......Page 5
Contents......Page 6
List of teaching cases......Page 9
Preface......Page 10
Acknowledgments......Page 12
 Examination of patients......Page 13
 Histopathology, immunophenotype, and molecular genetics......Page 16
 Other methods used in the study of cutaneous lymphoid infiltrates......Page 22
 Pseudomalignancy, premalignancy, and early malignancy......Page 23
 References......Page 24
Chapter 2 The “parapsoriases”: a riddle, wrapped in a mystery, inside an enigma......Page 26
 References......Page 33
Chapter 3 Mycosis fungoides......Page 34
 Onset of mycosis fungoides or exacerbation of undiagnosed disease under treatment with immunomodulatory agents......Page 35
 Clinical features......Page 37
 Association with other diseases......Page 41
 Histopathology, immunophenotype, and molecular genetics......Page 43
 Histopathologic differential diagnosis from inflammatory conditions......Page 62
 Clinical and histopathologic variants......Page 64
 Prognosis......Page 102
 References......Page 111
Chapter 4 Seary syndrome......Page 124
 Onset/progression under systemic therapies for benign inflammatory dermatoses......Page 125
 Clinical features......Page 126
 Histopathology, immunophenotype, and molecular genetics......Page 128
 Treatment......Page 134
 Prognosis......Page 135
 References......Page 139
Chapter 5 Primary cutaneous CD30+ lymphoproliferative disorders......Page 144
 Clinical features......Page 147
 Histopathology, immunophenotype, and molecular genetics......Page 148
 Clinicopathologic differential diagnosis......Page 157
 Treatment......Page 158
 Histopathology, immunophenotype, and molecular genetics......Page 165
 Treatment......Page 173
 Prognosis......Page 175
 References......Page 184
Chapter 6 Subcutaneous panniculitis‐like T‐cell lymphoma......Page 191
 Clinical features......Page 192
 Histopathology, immunophenotype, and molecular genetics......Page 193
 Differential diagnosis with other cutaneous NK/T‐cell lymphomas with prominent involvement of the subcutaneous tissue......Page 195
 Differential diagnosis with lupus panniculitis......Page 196
 Prognosis......Page 198
 References......Page 203
Chapter 7 Aggressive cutaneous cytotoxic lymphomas......Page 206
 Clinical features......Page 207
 Histopathology, immunophenotype, and molecular genetics......Page 208
 Clinical features......Page 214
 Histopathology, immunophenotype, and molecular genetics......Page 215
 Treatment......Page 218
 Prognosis......Page 219
 Histopathology, immunophenotype, and molecular genetics......Page 220
 Treatment......Page 224
 Prognosis......Page 225
 References......Page 227
 Clinical features......Page 230
 Histopathology, immunophenotype, and molecular genetics......Page 232
 Prognosis......Page 236
 References......Page 237
Chapter 9 Cutaneous CD4+ small/medium T‐cell lymphoproliferative disorder......Page 239
 Treatment......Page 240
 Prognosis......Page 241
 Final considerations......Page 243
 References......Page 244
 Histopathology, immunophenotype, and molecular genetics......Page 246
 Prognosis......Page 247
 References......Page 249
 Histopathology, immunophenotype, and molecular genetics......Page 250
 Treatment and prognosis......Page 252
 References......Page 253
 Clinical features, histopathology, immunophenotype, and molecular genetics......Page 254
 Treatment and prognosis......Page 257
 Clinical features, histopathology, immunophenotype, and molecular genetics......Page 258
 Treatment and prognosis......Page 259
 References......Page 261
 Clinical features......Page 265
 Histopathology, immunophenotype, and molecular genetics......Page 267
 Differential diagnosis of cutaneous follicle center lymphoma, diffuse type, from cutaneous diffuse large B‐cell lymphoma, leg t......Page 277
 Prognosis......Page 278
 References......Page 281
Chapter 14 Cutaneous marginal zone lymphoma (cutaneous MALT lymphoma) and variants......Page 284
 Clinical features......Page 287
 Histopathology, immunophenotype, and molecular genetics......Page 288
 Prognosis......Page 296
 Clinical features......Page 297
 Histopathology, immunophenotype, and molecular genetics......Page 298
 Prognosis......Page 299
 Histopathology, immunophenotype, and molecular genetics......Page 300
 Histopathology, immunophenotype, and molecular genetics......Page 302
 Treatment and prognosis......Page 303
 Clinical features......Page 304
 References......Page 305
Chapter 15 Cutaneous diffuse large B‐cell lymphoma, leg type......Page 309
 Clinical features......Page 310
 Histopathology, immunophenotype, and molecular genetics......Page 311
 Treatment......Page 318
 Prognosis......Page 319
 References......Page 322
Chapter 16 Intravascular large cell lymphomas......Page 325
 Histopathology, immunophenotype, and molecular genetics......Page 326
 Intravascular large B‐cell lymphoma colonizing hemangiomas......Page 328
 Treatment and prognosis......Page 329
 References......Page 333
 Clinical features......Page 336
 Treatment and prognosis......Page 337
 Histopathology, immunophenotype, and molecular genetics......Page 339
 Treatment and prognosis......Page 340
 Histopathology, immunophenotype, and molecular genetics......Page 341
 Treatment and prognosis......Page 343
 Clinical features......Page 344
 Treatment and prognosis......Page 345
 Histopathology, immunophenotype, and molecular genetics......Page 347
 Treatment and prognosis......Page 349
 Histopathology, immunophenotype, and molecular genetics......Page 350
 Treatment and prognosis......Page 351
 Histopathology, immunophenotype, and molecular genetics......Page 352
 Treatment and prognosis......Page 354
 Histopathology, immunophenotype, and molecular genetics......Page 355
 Histopathology, immunophenotype, and molecular genetics......Page 356
 Treatment and prognosis......Page 357
 Clinical features......Page 358
 Treatment and prognosis......Page 359
 References......Page 362
Chapter 18 Cutaneous lymphomas in immunosuppressed individuals......Page 366
 Histopathology, immunophenotype, and molecular genetics......Page 367
 Treatment and prognosis......Page 372
 Treatment and prognosis......Page 374
 CUTANEOUS LYMPHOPROLIFERATIVE DISORDERS IN OTHER IATROGENIC AND NON‐IATROGENIC IMMUNE DEFICIENCIES......Page 377
 Treatment and prognosis......Page 378
 References......Page 381
 Clinical features......Page 386
 Histopathology, immunophenotype, and molecular genetics......Page 387
 PROGRESSION TO DIFFUSE LARGE B‐CELL LYMPHOMA (RICHTER SYNDROME)......Page 392
 References......Page 395
 Clinical features......Page 397
 Histopathology, immunophenotype, and molecular genetics......Page 398
 Immunophenotype......Page 401
 Treatment and prognosis......Page 404
 References......Page 412
 Clinical features......Page 414
 Histopathology, immunophenotype, and molecular genetics......Page 415
 Immunophenotype......Page 418
 Prognosis......Page 421
 MATURE PLASMACYTOID DENDRITIC CELL PROLIFERATIONS ASSOCIATED WITH MYELOID NEOPLASMS......Page 422
 References......Page 423
Chapter 22 Cutaneous manifestations of other leukemias......Page 426
 References......Page 429
 Clinical features......Page 431
 Histopathology, immunophenotype, and molecular genetics......Page 432
 Histopathology, immunophenotype, and molecular genetics......Page 435
 Treatment and prognosis......Page 436
 References......Page 439
 Histopathology, immunophenotype, and molecular genetics......Page 442
 Treatment and prognosis......Page 444
 References......Page 447
Chapter 25 Cutaneous composite lymphomas......Page 448
 Histopathology, immunophenotype, and molecular genetics......Page 449
 References......Page 453
Chapter 26 Nonneoplastic cutaneous signs of systemic lymphomas......Page 455
 References......Page 464
Chapter 27 Cutaneous lymphomas in children and adolescents......Page 466
 References......Page 473
Chapter 28 Pseudolymphomas of the skin......Page 477
 Lupus panniculitis......Page 513
 Other pseudolymphomas associated with cutaneous lupus erythematosus......Page 515
 References......Page 558
Chapter 29 The cutaneous “atypical lymphoid proliferation”......Page 566
 References......Page 568
Index......Page 569