Severe Sepsis and Septic Shock - Understanding a Serious Killer

00 preface_Severe Sepsis and Sepsis Shock - Understanding a Serious Killer......Page 1
Part 1......Page 13
Epidemiology of Severe Sepsis and Septic Shock......Page 15
Part 2......Page 37
Septic Shock by Gram-Negative Infections: Role of Outer Membrane Proteins......Page 39
Transfusion-Associated Bacterial Sepsis......Page 59
Part 3......Page 81
The Autopsy Pathology of Sepsis-Related Death......Page 83
Part 4......Page 113
Biomarkers and Physiological Agents in Severe Sepsis and Septic Shock......Page 115
Immune Cell Dysfunction as a Consequence of Severe Sepsis......Page 137
Microparticles and Exosomes: Are They Part of Important Pathways in Sepsis Pathophysiology?......Page 167
Cellular Mechanisms of MOF During Severe Sepsis and Septic Shock......Page 179
Impact of Severe Sepsis or Septic Shock on Drug Response......Page 199
Part 5......Page 213
Update in the Treatment of Severe Sepsis and Septic Shock......Page 215
Management of Severe Sepsis and Septic Shock......Page 239
Applied Physiology and the Hemodynamic Management of Septic Shock Utilizing the Physiologic Optimization Program......Page 267
Part 6......Page 285
Management of Septic Shock in Children......Page 287
Septic Shock in Neonates......Page 297
Part 7......Page 321
Septic Shock in Obstetrics and Gynecology......Page 323
Part 8......Page 347
Alternative Therapies for Septic Shock: Beyond Early Goal-Directed Therapy......Page 349
Hormonal Therapies in Severe Sepsis......Page 371
Anti-Inflammatory Role of Natural Polyphenols and Their Degradation Products......Page 391
Part 9......Page 423
Cellular and Molecular Markers of Outcome in Septic Shock......Page 425