Separation of Enantiomers

Content: INTRODUCTION: A SURVEY OF HOW AND WHY TO SEPARATE ENANTIOMERS    Classical Methods    Kinetic Resolution ('KR')    Dynamic Kinetic Resolution ('DKR')    Divergent Reactions of a Racemic Mixture ('DRRM')    Other Methods        STOICHIOMETRIC KINETIC RESOLUTION REACTIONS    Introduction    Kinetic Treatment    Chiral Reagents and Racemic Substrates    Enantiodivergent Formation of Chiral Product    Enantioconvergent Reactions    Diastereomer Kinetic Resolution    Some Applications of Kinetic Resolution    Conclusion        CATALYTIC KINETIC RESOLUTION    Introduction    Kinetic Resolution of Alcohols    Kinetic Resolution of Epoxides    Kinetic Resolution of Amines    Kinetic Resolution of Alkenes    Kinetic Resolution of Carbonyl Derivatives    Kinetic Resolution of Sulfur Compounds    Kinetic Resolution of Ferrocenes    Conclusions        APPLICATION OF ENZYMES IN KINETIC RESOLUTIONS, DYNAMIC KINETIC RESOLUTIONS AND DERACEMIZATION REACTIONS    Introduction    Kinetic Resolutions Using Hydrolytic Enzymes    Dynamic Kinetic Resolution    Deracemization    Enantioconvergent Reactions    Conclusions        DYNAMIC KINETIC RESOLUTION (DKR)    Introduction    Definition and Classification    Dynamic Kinetic Resolution (DKR)    Mathematical Expression    DKR-Related Methods    Concluding Remarks        ENANTIODIVERGENT REACTIONS: DIVERGENT REACTIONS ON A RACEMIC MIXTURE AND PARALLEL KINETIC RESOLUTION    Introduction: The Conceptual Basis for Kinetic Resolution and Enantiodivergent Reactions    Divergent RRM Using a Single Chiral Reagent: Ketone Reduction    Divergent RRM under Oxidative Conditions    Organometallic Reactions and Regiodivergent RRM    Regiodivergent RRM in Selective Reactions of Difunctional Substrates    Divergent RRM Using Two Chiral Reagents: Parallel Kinetic Resolution (PKR)    Conclusion        RARE, NEGLECTED AND POTENTIAL SYNTHETIC METHODS FOR THE SEPARATION OF ENANTIOMERS    Resolution through the Selfish Growth of Polymers: Stereoselective Polymerization    Resolution through Photochemical Methods    Combinations of Crystallization and Racemization    Destruction then Recreation of Stereocentres: Enantioselective Protonations    Dynamic Combinatorial Chemistry    Asymmetric Autocatalysis    Miscellaneous    Concluding Remarks        Index