Schizophrenia : challenging the orthodox

Book Cover......Page 1
Title......Page 2
Copyright......Page 4
Contents......Page 5
Foreword......Page 7
Preface......Page 9
Contributors......Page 12
1 Brain abnormalities in schizophrenia and in those at risk of it......Page 16
2 Visualizing the cerebral alterations that underlie auditory hallucinations in schizophrenia......Page 21
3 Can we find the genes that predispose to schizophrenia?......Page 30
4 Genes for schizophrenia can be detected-data from Iceland implicates neuregulin 1......Page 35
5 Pharmacogenetics is the real future of genetic research in schizophrenia......Page 42
6 Can the social environment cause schizophrenia?......Page 55
7 The paradox of emotional dysfunction in ‘non-affective’ psychosis......Page 64
8 Risk and protective factors......Page 72
9 What is the relationship between methamphetamine andcannabis abuse and schizophrenia?......Page 79
10 Prediction of psychosis is necessary and possible......Page 86
11 The use of concepts in relation to early intervention in psychosis: a critical discussion......Page 95
12 Is the relationship between duration of untreated psychosis and outcome a result of premorbid deficits?......Page 101
13 Is early intervention a waste of valuable resources?......Page 106
14 Why antipsychotics are anti-‘psychotic’......Page 112
15 ‘Gone to pot’: pharmacological evidence supporting the contribution of cannabinoid receptor function to psychosis......Page 124
16 Schizophenia represents a failure to regulate dopamine systems......Page 134
17 Schizophrenia is a disorder of consciousness......Page 141
18 Does cognitive behaviour therapy work in schizophrenia?......Page 147
19 Cognitive remediation is better than cognitive behaviour therapy......Page 155
20 The shared genetic architecture which underlies schizophrenia and bipolar disorder......Page 164
21 Are there structural brain differences between schizophrenia and bipolar disorder?......Page 174
22 Functional neural abnormalities in schizophrenia and bipolar disorder: are they similar or different?......Page 183
23 Childhood similarities and differences between schizophrenia and bipolar disorder......Page 195
Index......Page 203