Role of Blood Flow in Atherogenesis: Proceedings of the International Symposium, Hyogo, October 1987

Front Matter....Pages I-XV
Front Matter....Pages 1-1
Establishing the Hemodynamic Determinants of Human Plaque Configuration, Composition and Complication....Pages 3-10
Distribution and Endothelial Morphology of Atherosclerotic Lesions at Bifurcations and Curves of Human Cerebral Arteries....Pages 11-18
Observations on Carotid Bifurcation Atherosclerosis in Human Cadavers....Pages 19-23
Localization of Lipids and Cell Population in Atheromatous Lesions in Aorta and Its Main Arterial Branches in Patients with Hypercholesterolemia....Pages 25-31
Underlying Morphological Changes in the Arterial Wall at Bifurcations for Atherogenesis....Pages 33-40
The Relationship Between Intimal Thickening and the Hemodynamic Environment of the Arterial Wall....Pages 41-46
The Role of Haemodynamics in the Proliferative Lesions of Atherosclerosis....Pages 47-53
Secondary Flow and Atherogenesis....Pages 55-59
Front Matter....Pages 61-61
The Utility of Correlations Between Model Flow Studies and Vessel Pathology in Describing Atherogenesis....Pages 63-65
Flow Patterns and Preferred Sites of Atherosclerosis in Human Coronary and Cerebral Arteries....Pages 67-72
Early Atherosclerosis and Pulsatile Flow in the Human Carotid Bifurcation....Pages 73-79
Flow Separation and Horseshoe Vortex in a Tube with Side Branches During Pulsatile Flow....Pages 81-90
Flow Studies in True-to-Scale Models of Human Renal Arteries....Pages 91-96
Unsteady, Separated Laminar Flow in Non-Uniform Vessels....Pages 97-102
Effects of Phase Relationships on Wall Shear Stress in Curved and Straight Elastic Artery Models....Pages 103-108
Wall Shear Stress Distribution Patterns in Arterial Stenosis Models Measured with an Electrochemical Technique....Pages 109-116
Intraoperative Evaluation of Blood Velocity Waveforms in Different Coronary Artery Bypass Graft....Pages 117-122
The Role of Flow Separation and Its Prediction in Arterial Flows....Pages 123-129
Numerical Simulation of a Blood Flow in a Stenosed Tube....Pages 131-137
Sinusoidal Oscillatory Flow in a Strongly Curved Tube....Pages 139-143
Front Matter....Pages 61-61
Visualization of Velocity Profile and Measurement of Wall Shear Stress in Branched Square Tube Using Laser-Induced Fluorescence Method....Pages 145-150
Front Matter....Pages 151-151
Cellular Reactions to Blood Flow....Pages 153-156
 In vivo Responses of Endothelial Cells to Hemodynamic Stress....Pages 157-161
Morphological Changes in the Flow Loaded Canine Carotid Artery....Pages 163-169
Ultrastructural Changes in the Endothelial Surface of Rat Carotid Artery Induced by Blood Flow Load....Pages 171-177
Distribution of Wall Shear Stress and Microfilament Bundles in Endothelial Cells in Canine Coronary Artery in vivo ....Pages 179-184
Adaptive Enlargement of Arteries in Response to Increased Flow and Increased Intimal Plaque....Pages 185-188
The Effect of a Fluid-Imposed Shear Stress on the Mechanical Properties of Cultured Endothelial Cells....Pages 189-194
The Effect of Fluid Shear Stress on the Growth Behavior of Vascular Endothelial Cells in vitro ....Pages 195-200
Turbulence, Disturbed Flow, and Vascular Endothelium....Pages 201-204
Effects of Blood Flow on Development of Atheromatous Plaques at an Experimental Inter-Carotid Anastomosis (Model Carotid Bifurcation)....Pages 205-208
Arterial Tortuosity....Pages 209-212
Front Matter....Pages 213-213
Wall Mass Transport and Other Mechanisms Underlying Atherogenesis....Pages 215-216
The Effect of Centrifugal Force on Glycosaminoglycans Synthesis and Cell Proliferation of Vascular Smooth Muscle Cells in Culture....Pages 217-222
An in vitro Assay System for Measuring Both Vascular Permeability and Endothelial Cell Damage....Pages 223-229
Endothelial Injury and Accumulation of Cholesterol Ester Derived from Circulating Lipoproteins....Pages 231-236
The Modulation of Transport Through the Arterial Wall....Pages 237-243
Effect of Tissue Hypoxia on the Development of Atherosclerosis....Pages 245-251
An Hypothesis for the Localization of Atherogenesis and Its Relationship to Endothelial Regulation and Transport....Pages 253-259
Models of Endothelial Cell Junctions....Pages 261-267
Back Matter....Pages 269-272